Is it necessary to dissect levels i and IIB in hypopharyngeal cancer?

Acta Oto-Laryngologica

Volumn 130, Issue 6, 2010, Pages 747-752

  Wiegand, Susanne ^a   Esters, Judith ^a   M̈ller, Hans Helge ^b   Jäcker, Tim ^c   Roeßler, Marion ^c   Werner, Jochen A ^a   Sesterhenn, Andreas M ^a  

^a Department of Otolaryngology Head and Neck Surgery ^*  (Germany)

^b Inst Med Biometr and Epidemiol   (Germany)

^c UKGM   (Germany)

Author keywords

HNSCC; Hypopharynx; Neck dissection; Treatment

Indexed keywords

ADULT; AGED; ARTICLE; CANCER RADIOTHERAPY; CANCER STAGING; CLINICAL ARTICLE; COMORBIDITY; CONTROLLED STUDY; FEMALE; FUNCTIONAL STATUS; HISTOPATHOLOGY; HUMAN; HYPOPHARYNX CANCER; LYMPH NODE METASTASIS; MALE; NECK DISSECTION; OPERATION DURATION; POSTOPERATIVE CARE; PRIORITY JOURNAL; QUALITY OF LIFE; TREATMENT OUTCOME;

ADULT; AGED; CARCINOMA, SQUAMOUS CELL; COMBINED MODALITY THERAPY; FEMALE; HUMANS; HYPOPHARYNGEAL NEOPLASMS; HYPOPHARYNX; LYMPH NODES; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NECK DISSECTION; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PROGNOSIS; RADIOTHERAPY, ADJUVANT; RETROSPECTIVE STUDIES;

EID: 77952272333     PISSN: 00016489     EISSN: 16512553     Source Type: Journal    
DOI: 10.3109/00016480903384168     Document Type: Article

References (20)

1. Santoro R, Franchi A, Gallo O, Burali G, de'Campora E. Nodal metastases at level IIb during neck dissection for head and neck cancer: clinical and pathologic evaluation. Head Neck 2008;30:1483-7.
2. Ferlito A, Rinaldo A, Silver CE, Gourin CG, Shah JP, Clayman GL, et al. Elective and therapeutic selective neck dissection. Oral Oncol 2006;42:14-25.
3. Ferlito A, Silver CE, Rinaldo A. Neck dissection: present and future? Eur Arch Otorhinolaryngol 2008;265:621-6.
4. Robbins KT. Indications for selective neck dissection: when, how, and why. Oncology (Williston Park) 2000;14:1455-64; discussion 67-9.
5. Schmitz S, Machiels J, Weynand B, Gregoire V, Hamoir M. Results of selective neck dissection in the primary treatment of head and neck squamous cell carcinoma. Eur Arch Otorhinolaryngol 2009;266:437-43.
6. Varghese BT, Sebastian P, Mathew A. Treatment outcome in patients undergoing surgery for carcinoma larynx and hypopharynx - a follow-up study. Acta Otolaryngol 2009;12:1-6.
7. Remmert S, Rottmann M, Reichenbach M, Sommer K, Friedrich HJ. Lymph node metastasis in head-neck tumors. Laryngorhinootologie 2001;80:27-35.
8. Schiefke F, Akdemir M, Weber A, Akdemir D, Singer S, Frerich B. Function, postoperative morbidity, and quality of life after cervical sentinel node biopsy and after selective neck dissection. Head Neck 2009;31:503-12.
9. Clopper C, Pearson S. The use of confidence or fiducial limits illustrated in the case of the binomial. Biometrika 1934;26:404-13.
10. Wenig BL, Applebaum EL. The submandibular triangle in squamous cell carcinoma of the larynx and hypopharynx. Laryngoscope 1991;101:516-18.
11. Werner JA, Dünne AA, Myers JN. Functional anatomy of the lymphatic drainage system of the upper aerodigestive tract and its role in metastasis of squamous cell carcinoma. Head Neck 2003;25:322-32.
12. Candela FC, Kothari K, Shah JP. Patterns of cervical node metastases from squamous carcinoma of the oropharynx and hypopharynx. Head Neck 1990;12:197-203.
13. Li XM, Wei WI, Guo XF, Yuen PW, Lam LK. Cervical lymph node metastatic patterns of squamous carcinomas in the upper aerodigestive tract. J Laryngol Otol 1996;110:937-41.
14. Buckley JG, MacLennan K. Cervical node metastases in laryngeal and hypopharyngeal cancer: a prospective analysis of prevalence and distribution. Head Neck 2000;22:380-5.
15. Mercante G, Bacciu A, Oretti G, Ferri T. Involvement of level I neck lymph nodes and submandibular gland in laryngeal and/or hypopharyngeal squamous cell carcinoma. J Otolaryngol 2006;35:108-11.
16. Chone CT, Crespo AN, Rezende AS, Carvalho DS, Altemani A. Neck lymph node metastases to the posterior triangle apex: evaluation of clinical and histopathological risk factors. Head Neck 2000;22:564-71.
17. Silverman DA, El-Hajj M, Strome S, Esclamado RM. Prevalence of nodal metastases in the submuscular recess (level IIb) during selective neck dissection. Arch Otolaryngol Head Neck Surg 2003;129:724-8.
18. Corlette TH, Cole IE, Albsoul N, Ayyash M. Neck dissection of level IIb: is it really necessary? Laryngoscope 2005;115:1624-6.
19. Kim YH, Koo BS, Lim YC, Lee JS, Kim SH, Choi EC. Lymphatic metastases to level IIb in hypopharyngeal squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 2006;132:1060-4.
20. Villaret AB, Piazza C, Peretti G, Calabrese L, Ansarin M, Chisa F, et al. Multicentric prospective study on the prevalence of sublevel IIb metastases in head and neck cancer. Arch Otolaryngol Head Neck Surg 2007;133:897-903.