Encephalopathy from lead poisoning masquerading as a flu-like syndrome in an autistic child

Pediatric Emergency Care

Volumn 26, Issue 5, 2010, Pages 370-373

  George, Mathew ^a   Heeney, Matthew M ^a   Woolf, Alan D ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Anemia; Autism; Encephalopathy; Lead poisoning; Plumbism; Toxicity

Indexed keywords

DIMERCAPROL; EDETIC ACID; LEAD; SUCCIMER; CHELATING AGENT;

ABDOMINAL RADIOGRAPHY; ANAMNESIS; ANEMIA; ARTICLE; AUTISM; BEHAVIOR DISORDER; BRAIN DISEASE; CASE REPORT; CHELATION THERAPY; CHILD; CLINICAL FEATURE; COLIC; CONSCIOUSNESS DISORDER; DISEASE SEVERITY; EMERGENCY WARD; FLU LIKE SYNDROME; GASTROENTERITIS; HOSPITALIZATION; HUMAN; INTENSIVE CARE UNIT; LEAD POISONING; MALE; PALLOR; PATIENT REFERRAL; VOMITING; COMPLICATION; DIFFERENTIAL DIAGNOSIS; FOLLOW UP; INFLUENZA, HUMAN; LEAD POISONING, NERVOUS SYSTEM, CHILDHOOD; PRESCHOOL CHILD; PROCEDURES;

AUTISTIC DISORDER; CHELATING AGENTS; CHELATION THERAPY; CHILD, PRESCHOOL; DIAGNOSIS, DIFFERENTIAL; FOLLOW-UP STUDIES; HUMANS; INFLUENZA, HUMAN; INTENSIVE CARE UNITS, PEDIATRIC; LEAD POISONING, NERVOUS SYSTEM, CHILDHOOD; MALE;

EID: 77952267700     PISSN: 07495161     EISSN: None     Source Type: Journal    
DOI: 10.1097/PEC.0b013e3181db2237     Document Type: Article

References (18)

1. Moyer PA, Pivetz T, Dignam TA, et al. CDC Centers for Disease Control and Prevention (CDC). Surveillance for elevated blood lead levels among children - United States 1997-2001. MMWR. 2003; 52 (SS10) : 1-21.
2. Woolf AD, Goldman R, Bellinger DC. Update on the clinical management of childhood lead poisoning. Pediatr Clin North Am. 2007; 54 (2) : 271-294.
3. American Academy of Pediatrics Committee on Environmental Health. Lead exposure in children: prevention, detection, and management. Pediatrics. 2005; 116 (4) : 1036-1046.
4. Lin-Fu JS. Undue absorption of lead among children-a new look at an old problem. N Engl J Med. 1972; 286 (13) : 702-710.
5. Shannon M, Graef JW. Lead intoxication in children with pervasive developmental disorders. J Toxicol Clin Toxicol. 1996;34:177.
6. Accardo P, Whitman B, Caul J, et al. Autism and plumbism. A possible association. Clin Pediatr (Phila). 1988; 27 (1) : 41-44.
7. Sood A, Midha V, Sood N. Pain in abdomen-do not forget lead poisoning. Indian J Gastroenterol. 2002; 21 (6) : 225-226.
8. Shiri R, Ansari M, Ranta M, et al. Lead poisoning and recurrent abdominal pain. Ind Health. 2007; 45 (3) : 494-496.
9. Kwong WT, Friello P, Semba RI. Interactions between iron deficiency and lead poisoning: epidemiology and pathogenesis. Sci Total Environ. 2004;330(1-3):21-37.
10. Wright RO, Shannon MW, Wright RJ, et al. Association between iron deficiency and low level lead poisoning in an urban primary care clinic. Am J Public Health. 1999; 89 (7) : 1049-1053.
11. Liebelt EL, Schonfeld DJ, Gallagher P. Elevated blood lead levels in children are associated with lower erythropoietin concentrations. J Pediatr. 1999;134:107-109.
12. Kales SN, Christophi CA, Saper RB. Hematopoietic toxicity from lead-containing ayurvedic medications. Med Sci Monit. 2007; 13 (7) : CR295-CR298.
13. Gordon RA, Roberts G, Amin Z, et al. Aggressive approach in the treatment of acute lead encephalopathy with an extraordinarily high concentration of lead. Arch Pediatr Adolesc Med. 1998; 152 (11) : 1100-1104.
14. Raber SA. The dense metaphyseal band sign. Radiology. 1999;211:773-774.
15. Laor T, Jaramillo D. Metaphyseal abnormalities in children: pathophysiology and radiologic appearance. AJR. 1993;161:1029-1036.
16. Blickman JG, Wilkinson RH, Graef JW. The radiologic "lead band" revisited. AJR. 1986;146:245-247.
17. Swischuk L. Metaphyseal abnormalities. In: Tracy TM, ed. Differential Diagnosis in Pediatric Radiology. Baltimore, MD: Williams and Wilkins; 1984: 226-229.
18. Diament M, Kangarloo H, Kodroff M, et al. Dense metaphyseal bands in patients on long term parenteral nutrition. Pediatr Radiol. 1981;11:207-209.