Design and fabrication of PLGA sandwiched cell/fibrin constructs for complex organ regeneration

Journal of Bioactive and Compatible Polymers

Volumn 25, Issue 3, 2010, Pages 229-240

  Wang, Xiaohong ^a   Sui, Shaochun ^a   Yan, Yongnian ^a   Zhang, Renji ^a  

^a TSINGHUA UNIVERSITY   (China)

Author keywords

Adipose stem cells; Extraction; Poly(DL lactic co glycolic acid); Polyurethane; Predesigned mold; Vascular system

Indexed keywords

ADIPOSE STEM CELLS; CAPROLACTONE; CELL COMPATIBILITY; COMPLEX ORGANS; GLYCOLIC ACIDS; HEXAMETHYL DIISOCYANATE; IN-VITRO; IN-VIVO; MICROPOROUS; POLY(DL-LACTIC-CO-GLYCOLIC ACID); SMOOTH MUSCLES; STEM CELL; TRILAYERS; VASCULAR SMOOTH MUSCLES; VASCULAR SYSTEM;

ACIDS; BIOMECHANICS; CELL CULTURE; ETHYLENE; ETHYLENE GLYCOL; LEAKAGE (FLUID); MECHANICAL PROPERTIES; MOLDS; MUSCLE; OXYGEN; TISSUE ENGINEERING;

STEM CELLS;

ALGINIC ACID; BIOMATERIAL; FIBRIN; FIBRINOGEN; GELATIN; POLYGLACTIN; POLYURETHAN;

ADIPOSE TISSUE CELL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CELL VIABILITY; COMPOSITE MATERIAL; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; MATERIALS TESTING; METABOLITE; MUSCLE REGENERATION; NONHUMAN; POROSITY; PROCESS DESIGN; RAT; STEM CELL; TENSILE STRENGTH; TISSUE ENGINEERING; VASCULAR SMOOTH MUSCLE;

EID: 77952256809     PISSN: 08839115     EISSN: 15308030     Source Type: Journal    
DOI: 10.1177/0883911510365661     Document Type: Article

References (27)

1. Borenstein, J.T., Terai, H., King, K.R., Weinberg, E.J., Kaazempur-Mofrad, M.R. and Vacanti, J.P. (2002). Microfabrication Technology for Vascularized Tissue Engineering, Biomed. Microdevices, 4: 167-175.
2. Wang, X.H., Yan, Y.N. and Zhang, R.J. (2007). Rapid Prototyping as a Tool for Manufacturing Bioartificial Livers, Trends Biotechnol., 25: 505-513.
3. Xu, W., Wang, X.H., Yan, Y.N. and Zhang, R.J. (2008). Rapid Prototyping of Polyurethane for the Creation of Branched Vascular Systems, J. Bioact. Compat. Polym., 23: 154-170. (Featured by Nature China on May 3, 2008 ).
4. Wang, X.H., Yan, Y.N. and Zhang, R.J. (2009). Recent Trends and Challenges in Complex Organ Manufacturing, Tissue Eng: Part B, in press.
5. Rouwkema, J., Rivron, N.C. and van Blitterswijk, C.A. (2008). Vascularization in Tissue Engineering, Trends Biotechnol., 26: 434-441.
6. Caspi, O., Lesman, A., Basevitch, Y., Gepstein, A., Arbel, G., Habib, M. et al. (2007). Tissue Engineering of Vascularized Cardiac Muscle from Human Embryonic Stem Cells, Circ. Res., 100: 263-272.
7. Yin, D.Z., Wang, X.H., Yan, Y.N. and Zhang, R.J. (2007). Preliminary Studies on Peripheral Nerve Regeneration along a New Polyurethane Conduit, J. Bioact. Compat. Polym., 22: 143-159.
8. Yan, Y.N., Wang, X.H., Yin, D.Z. and Zhang, R.J. (2007). A New Polyurethane/Heparin Vascular Graft for Small-Caliber Vein Repair, J. Bioact. Compat. Polym., 22: 323-341.
9. Kim, B.S., Putnam, A.J., Kulik, T.J. and Mooney, D.J. (1998). Optimizing Seeding, and Culture Methods to Engineer Smooth Muscle Tissue on Biodegradable Polymer Matrices, Biotechol. Bioeng., 57: 46-54.
10. Ziegler, T. and Nerem, R.M. (1994). Tissue Engineering a Blood Vessel: Regulation of Vascular Biology by Mechanical Stresses, J. Cell Biochem., 56: 204-209.
11. Grassl, E.D., Oegema, T.R. and Tranquillo, R.T. (2002). Fibrin as an Alternative Biopolymer to Type-I Collagen for the Fabrication of a Media Equivalent, J. Biomed. Mater. Res., 60: 607-612.
12. Aper, T., Teebken, O.E., Steinhoff, G. and Haverich, A. (2004). Use of a Fibrin Preparation in the Engineering of a Vascular Graft Model, Eur. J. Vasc Endovasc. Surg., 28: 296-302.
13. Yao, R., Zhang, R.J., Yan, Y.N. and Wang, X.H. (2009). In vitro Angiogenesis of 3D Tissue Engineered Adipose Tissue, J. Bioact. Compat. Polym., 24: 5-29.
14. Xu, M.E., Yan, Y.N., Liu, H.X., Yao, R. and Wang, X.H. (2008). Establishing a Multicellular Model by Three-Dimensional Cell-Assembly Technique for Metabolic Syndrome, Nature Precedings, Posted 8 Jan 2008.
15. Xu, M.E., Yan, Y.N., Liu, H.X., Yao, R. and Wang, X.H. (2009). Control Adipose-Derived Stromal Cells Differentiation into Adipose and Endothelial Cells in a 3-D Structure Established by Cell-Assembly Technique, J. Bioact. Compat. Polym., 24 (S1). 31-47.
16. Li, S.J., Xiong, Z., Wang, X.H., Yan, Y.N., Liu, H.X. and Zhang, R.J. (2009). Direct Fabrication of a Hybrid Cell/Hydrogel Construct via a Double-nozzle Assembling Technology, J. Bioact. Compat. Polym., 24: 249-265.
17. Li, S.J., Yan, Y.N., Xiong, Z., Weng, C.Y., Zhang, R.J. and Wang, X.H. (2009). Gradient Hydrogel Construct based on an Improved Cell Assembling System, J. Bioact. Compat. Polym., 24 (S1). 84-99.
18. Wang, X.H. and Sui, S.C. Optimizing the Step by Step Forming Processes for Fabricating a PLGA Sandwiched Cell/Hydrogel Construct, J. Bioact. Compat. Polym., submitted.
19. Wang, X.H. and Sui, S.C. Characterization of a PLGA Sandwiched Cell/ Fibrin Construct and Induction of the Adipose Stem Cells (ADSCs) into Smooth Muscle Cells, J. Bioact. Compat. Polym., submitted.
20. Wang, X.H. and Sui, S.C. Pulsatile Culture of a PLGA Sandwiched Cell/ Hydrogel Construct Fabricated by a Step by Step Mold/Extraction Method, Artif. Organs., submitted.
21. Xu, W., Wang, X.H., Yan, Y.N. and Zhang, R.J. (2008). A Olyurethane-Gelatin Hybrid Construct for the Manufacturing of Implantable Bioartificial Livers, J. Bioact. Compat. Polym., 23: 409-422.
22. Cui, T.K., Yan, Y.N., Zhang, R.J., Liu, L., Xu, W. and Wang, X.H. (2009). Rapid Prototyping of a Double Layer Polyurethane-Collagen Conduit for Peripheral Nerve Regeneration, Tissue Eng. Part C, 15: 1-9.
23. Cui, T.K., Wang, X.H., Yan, Y.N. and Zhang, R.J. (2009). Rapid Prototyping a New Polyurethane-Collagen Conduit and its Schwann Cell Compatibility, J. Bioact. Compat. Polym., 24 (S1). 5-17.
24. Wang, X.H., Cui, T.K., Yan, Y.N., Zhang, R.J. (2009). Peroneal Nerve Regeneration using a Unique Bilayer Polyurethane-Collagen Guide Conduit, J. Bioact. Compat. Polym., 24: 109-127.
25. Walden, R., LItalien, G.J., Megerman, J. and Abbott, W.M. (1980). Matched Elastic Properties and Successful Arterial Grafting, Arch. Surg., 115: 1166-1169.
26. Stekelenburg, M., Rutten, M.C.M., Snoeckx, L.H.E.H. and Baaijens, F.P.T. (2009). Dynamic Straining Combined with Fibrin Gel Cell Seeding Improves Strength of Tissue-Engineered Small-Diameter Vascular Grafts, Tissue Eng. Part A, 15: 1081-1089.
27. Kim, B.S. and Mooney, D.J. (1998). Engineering Smooth Muscle Tissue with a Predefined Structure, J. Biomed. Mater. Res., 41: 322-332.