Unilateral hand-foot syndrome: An extraordinary side effect of capecitabine

Cutaneous and Ocular Toxicology

Volumn 29, Issue 2, 2010, Pages 140-142

  Disel, Umut ^a   Gürkut, Özlem ^b   Abali, Hüseyin ^a   Kaleaǧasi, Hakan ^c   Mertsoylu, Hüseyin ^a   Özyilkan, Özgür ^a   Saif, Muhammad Wasif ^d  

^a BASKENT UNIVERSITY   (Turkey)

^b Turkish Republic of Northtern Cyprus   (Cyprus)

^c MERSIN UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

^d YALE CANCER CENTER   (United States)

Author keywords

Capecitabine; Hand foot syndrome; HFS; Stroke

Indexed keywords

CAPECITABINE;

ADVANCED CANCER; AGED; ARTICLE; CASE REPORT; DRUG WITHDRAWAL; ERYTHEMA; HAND FOOT SYNDROME; HUMAN; LIMB PAIN; MALE; MULTIPLE CYCLE TREATMENT; PARESTHESIA; STOMACH CANCER; UNILATERAL HAND FOOT SYNDROME;

AGED; ANTIMETABOLITES, ANTINEOPLASTIC; ATROPHY; DEOXYCYTIDINE; DIHYDROURACIL DEHYDROGENASE (NADP); ERYTHEMA; FLUOROURACIL; FOOT; FUNCTIONAL LATERALITY; HAND; HUMANS; MALE; STOMACH NEOPLASMS;

EID: 77952168214     PISSN: 15569527     EISSN: 15569535     Source Type: Journal    
DOI: 10.3109/15569521003699585     Document Type: Article

References (10)

1. Lokich JJ, Moore C. Chemotherapy-associated palmarplantar erythrodysesthesia syndrome. Ann Intern Med 1984; 101(6):798-799.
2. Leo S, Tatulli C, Taveri R, Campanella GA, Carrieri G, Colucci G. Dermatological toxicity from chemotherapy containing 5-fluorouracil. J Chemother 1994; 6(6): 423-426.
3. Saif MW, Elfiky A, Diasio R. Hand-foot syndrome variant in a dihydropyrimidine dehydrogenase-deficient patient treated with capecitabine. Clin Colorectal Cancer 2006; 6(3):219-223.
4. Saif MW, Katirtzoglou NA, Syrigos KN. Capecitabine: an overview of the side effects and their management [review]. Anticancer Drugs 2008; 19(5):447-464.
5. Cassidy J, Twelves C, Van Cutsem E, Hoff P, Bajetta E, Boyer M, et al. First-line oral capecitabine therapy in metastatic colorectal cancer: a favorable safety profile compared with intravenous 5-fluorouracil/leucovorin. Ann Oncol 2002;13(4):566-575.
6. Hesse M, Jahnke MT, Ehret R, Mauritz KH. Shoulder- Hand Syndrome in Hemiplegic Patients: Temperature, Sympathetic Skin Responses, and Nerve Latencies of the Affected and Nonaffected Upper Extremity. 1995; Neurorehabilitation and Neural Repair 9(4): 229-233.
7. Korpelainen JT, Tolonen U, Sotaniemi KA, Myllyla VV. Suppressed sympathetic skin response in brain infarction. Stroke 1994; 24(9):1389-1392.
8. Milano G, Etienne-Grimaldi MC, Mari M, Lassalle S, Formento JL, Francoual M, et al. Candidate mechanisms for capecitabine-related hand-foot syndrome. Br J Clin Pharmacol 2008; 66(1):88-95.
9. Saif MW, Elfiky AA. Identifying and treating fluoropyrimidine- associated hand-and-foot syndrome in white and non-white patients. J Support Oncol 2007; 5(7): 337-343.
10. http://clinicaltrials.gov/ct2/show/NCT00751101 (accessed 7 January 2010).