Inhibition of transforming growth factor-β signalling attenuates interleukin (IL)-18 plus IL-2-induced interstitial lung disease in mice

Clinical and Experimental Immunology

Volumn 160, Issue 3, 2010, Pages 394-402

  Segawa, S ^a   Goto, D ^a   Yoshiga, Y ^a   Sugihara, M ^a   Hayashi, T ^a   Chino, Y ^a   Matsumoto, I ^a   Ito, S ^a   Sumida, T ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Activin receptor like kinase 5; Chemokines; Interstitial lung disease; Pathogenesis; SB 431542; TGF signalling

Indexed keywords

CHEMOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 18; INTERLEUKIN 2; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DISEASE COURSE; FEMALE; IMMUNOPATHOGENESIS; INTERSTITIAL LUNG DISEASE; MORTALITY; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ACUTE DISEASE; ANIMALS; ANTINEOPLASTIC AGENTS; BENZAMIDES; CHEMOKINES; DIOXOLES; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-18; INTERLEUKIN-2; INTERLEUKIN-6; KILLER CELLS, NATURAL; LUNG DISEASES, INTERSTITIAL; MICE; MICE, KNOCKOUT; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RNA, MESSENGER; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 77952163889     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2010.04094.x     Document Type: Article

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