Preparative isolation and purification of anti-tumor agent ansamitocin P-3 from fermentation broth of Actinosynnema pretiosum using high-performance counter-current chromatography

Journal of Separation Science

Volumn 33, Issue 9, 2010, Pages 1331-1337

  Yao, Yuqin ^a   Cheng, Zhihui ^a   Ye, Haoyu ^a   Xie, Yongmei ^a   He, Jing ^a   Tang, Minghai ^a   Shen, Tao ^a   Wang, Jiangman ^a   Zhou, Yan ^a   Lu, Zejun ^a   Luo, Feng ^a   Chen, Lijuan ^a   Yu, Luoting ^a   Yang, Jin Liang ^a   Peng, Aihua ^a   Wei, Yuquan ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Ansamitocin P 3; Anti tumor agent; Fermentation broth; High performance counter current chromatography; LC MS

Indexed keywords

ANTI-TUMOR AGENTS; ANTI-TUMORS; CRUDE SAMPLES; ETHYL ACETATES; FERMENTATION BROTHS; HIGH-PERFORMANCE COUNTER-CURRENT CHROMATOGRAPHY; MASS SPECTROSCOPY; METHANOL-WATER; PREPARATIVE ISOLATION; STRUCTURAL IDENTIFICATION; TWO-PHASE SOLVENT SYSTEM;

CHROMATOGRAPHY; ESTERS; HEXANE; MASS SPECTROMETRY; METHANOL; ORGANIC SOLVENTS; TUMORS;

FERMENTATION;

ANSAMITOCIN P 3;

ACTINOSYNNEMA PRETIOSUM; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; COUNTER CURRENT CHROMATOGRAPHY; DRUG ISOLATION; DRUG PURIFICATION; DRUG STRUCTURE; DRUG SYNTHESIS; FERMENTATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MEDICINAL PLANT; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTINEOPLASTIC AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUNTERCURRENT DISTRIBUTION; CULTURE MEDIA; FERMENTATION; GRAM-POSITIVE BACTERIA; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MAYTANSINE;

ACTINOSYNNEMA PRETIOSUM;

EID: 77952158012     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.200900746     Document Type: Article

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