Pharmacokinetics of gamithromycin in cattle with comparison of plasma and lung tissue concentrations and plasma antibacterial activity

Journal of Veterinary Pharmacology and Therapeutics

Volumn 33, Issue 3, 2010, Pages 227-237

  Huang, R A ^a   Letendre, L T ^a   Banav, N ^a   Fischer, J ^a   Somerville, B ^a  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GAMITHROMYCIN; MACROLIDE; UNCLASSIFIED DRUG; ZAC TRAN; ANTIINFECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CATTLE; COMPARTMENT MODEL; CONTROLLED STUDY; DISTRIBUTION VOLUME; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG DOSE COMPARISON; DRUG HALF LIFE; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG TISSUE LEVEL; FEMALE; IN VITRO STUDY; LUNG HOMOGENATE; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RECOMMENDED DRUG DOSE; SEX DIFFERENCE; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION; ANIMAL; BLOOD; BOVINAE; BOVINE RESPIRATORY DISEASE COMPLEX; CHEMISTRY; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LUNG; MANNHEIMIA HAEMOLYTICA; MICROBIAL SENSITIVITY TEST; VETERINARY;

BOS; BOVINAE;

ANIMALS; ANTI-BACTERIAL AGENTS; BOVINE RESPIRATORY DISEASE COMPLEX; CATTLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; LUNG; MACROLIDES; MALE; MANNHEIMIA HAEMOLYTICA; MICROBIAL SENSITIVITY TESTS;

EID: 77952132864     PISSN: 01407783     EISSN: 13652885     Source Type: Journal    
DOI: 10.1111/j.1365-2885.2009.01125.x     Document Type: Article

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