An RNA-hydrolyzing recombinant antibody exhibits an antiviral activity against classical swine fever virus

Biochemical and Biophysical Research Communications

Volumn 395, Issue 4, 2010, Pages 484-489

  Jun, Hye Ryeong ^a   Pham, Chuong D ^a   Lim, Seong In ^b   Lee, Suk Chan ^c   Kim, Yong Sung ^d   Park, Sun ^a   Kwon, Myung Hee ^a  

^a Ajou University School of Medicine   (South Korea)

^b Animal Plant and Fisheries Quarantine and Inspection Agency   (South Korea)

^c Sungkyunkwan University   (South Korea)

^d Ajou University   (South Korea)

Author keywords

3D8 scFv; Anti nucleic acid antibody; Antiviral activity; Catalytic antibody; Classical swine fever virus (CSFV); RNA hydrolysis

Indexed keywords

3D8 SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; ALPHA INTERFERON; BETA INTERFERON; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG; VIRUS RNA;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CELL LEVEL; CLASSICAL SWINE FEVER; CONTROLLED STUDY; CYTOPLASM; DRUG DETERMINATION; MOUSE; NONHUMAN; PESTIVIRUS; PRIORITY JOURNAL; RNA ANALYSIS; VIRUS CELL INTERACTION; VIRUS INHIBITION; VIRUS LOAD; VIRUS REPLICATION;

ANIMALS; ANTIBODIES, ANTINUCLEAR; ANTIBODIES, MONOCLONAL; ANTIVIRAL AGENTS; CELL LINE; CLASSICAL SWINE FEVER; CLASSICAL SWINE FEVER VIRUS; DOWN-REGULATION; HYDROLYSIS; INTERFERON TYPE I; RECOMBINANT PROTEINS; RIBONUCLEASES; RNA, VIRAL; SINGLE-CHAIN ANTIBODIES; SWINE; VIRUS REPLICATION;

CLASSICAL SWINE FEVER VIRUS;

EID: 77952110222     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.04.032     Document Type: Article

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