Primary cytomegalovirus infectious colitis complicating Crohn's disease successfully treated with oral valganciclovir

Journal of Crohn's and Colitis

Volumn 4, Issue 2, 2010, Pages 199-202

  Subramanian, Venkataraman ^a   Finlayson, Caroline ^a   Harrison, Thomas ^a   Rice, Phillip ^a   Pollok, Richard ^a  

^a ST GEORGE'S UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

CMV DNA quantification; Crohn's disease; Cytomegalovirus; Inflammatory bowel disease; Valganciclovir

Indexed keywords

ALANINE AMINOTRANSFERASE; ALENDRONIC ACID; ATOVAQUONE PLUS PROGUANIL; AZATHIOPRINE; C REACTIVE PROTEIN; CALCIUM; CEFOTAXIME; CIPROFLOXACIN; COLECALCIFEROL; DOXYCYCLINE; GANCICLOVIR; HYDROCORTISONE; MESALAZINE; METRONIDAZOLE; PREDNISOLONE; STEROID; VALGANCICLOVIR; VANCOMYCIN;

ABDOMINAL PAIN; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANEMIA; APPETITE DISORDER; ARTICLE; BACTERIUM DETECTION; CASE REPORT; CLINICAL FEATURE; CLOSTRIDIUM DIFFICILE; COLITIS; COLONOSCOPY; CROHN DISEASE; CYTOMEGALOVIRUS INFECTION; DISEASE DURATION; FEMALE; FEVER; HUMAN; MALAISE; MALARIA; MISSED ABORTION; NAUSEA; PHYSICAL EXAMINATION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; TREATMENT DURATION; VERNER MORRISON SYNDROME; WEIGHT REDUCTION;

ADULT; ANTIVIRAL AGENTS; COLITIS; CROHN DISEASE; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; DNA, VIRAL; FEMALE; GANCICLOVIR; HUMANS; IMMUNOCOMPROMISED HOST; IMMUNOSUPPRESSION; IMMUNOSUPPRESSIVE AGENTS; OPPORTUNISTIC INFECTIONS; TREATMENT OUTCOME; VIRAL LOAD;

EID: 77952106955     PISSN: 18739946     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.crohns.2009.11.004     Document Type: Article

References (18)

1. Pollok R.C. Viruses causing diarrhoea in AIDS. Novartis Found Symp 238 (2001) 276-283
2. Buckner F.S., and Pomeroy C. Cytomegalovirus disease of the gastrointestinal tract in patients without AIDS. Clin Infect Dis 17 4 (1993) 644-656
3. Criscuoli V., Rizzuto M.R., and Cottone M. Cytomegalovirus and inflammatory bowel disease: is there a link?. World J Gastroenterol 12 30 (2006) 4813-4818
4. Papadakis K.A., Tung J.K., Binder S.W., Kam L.Y., Abreu M.T., Targan S.R., et al. Outcome of cytomegalovirus infections in patients with inflammatory bowel disease. Am J Gastroenterol 96 7 (2001) 2137-2142
5. Toruner M., Loftus Jr. E.V., Harmsen W.S., Zinsmeister A.R., Orenstein R., Sandborn W.J., et al. Risk factors for opportunistic infections in patients with inflammatory bowel disease. Gastroenterology 134 4 (2008) 929-936
6. Hommes D.W., Sterringa G., van Deventer S.J., Tytgat G.N., and Weel J. The pathogenicity of cytomegalovirus in inflammatory bowel disease: a systematic review and evidence-based recommendations for future research. Inflamm Bowel Dis 10 3 (2004) 245-250
7. Wreghitt T.G., Teare E.L., Sule O., Devi R., and Rice P. Cytomegalovirus infection in immunocompetent patients. Clin Infect Dis 37 12 (2003) 1603-1606
8. Kandiel A., and Lashner B. Cytomegalovirus colitis complicating inflammatory bowel disease. Am J Gastroenterol 101 12 (2006) 2857-2865
9. Pfau P., Kochman M.L., Furth E.E., and Lichtenstein G.R. Cytomegalovirus colitis complicating ulcerative colitis in the steroid-naive patient. Am J Gastroenterol 96 3 (2001) 895-899
10. Eyre-Brook I.A., and Dundas S. Incidence and clinical significance of colonic cytomegalovirus infection in idiopathic inflammatory bowel disease requiring colectomy. Gut 27 12 (1986) 1419-1425
11. Criscuoli V., Casa A., Orlando A., Pecoraro G., Oliva L., Traina M., et al. Severe acute colitis associated with CMV: a prevalence study. Dig Liver Dis 36 12 (2004) 818-820
12. Maconi G., Colombo E., Zerbi P., Sampietro G.M., Fociani P., Bosani M., et al. Prevalence, detection rate and outcome of cytomegalovirus infection in ulcerative colitis patients requiring colonic resection. Dig Liver Dis 37 6 (2005) 418-423
13. Just-Nubling G., Korn S., Ludwig B., Stephan C., Doerr H.W., and Preiser W. Primary cytomegalovirus infection in an outpatient setting - laboratory markers and clinical aspects. Infection 31 5 (2003) 318-323
14. Subramanian V. Distinguishing primary CMV infection from reactivation of latent infection. Dig Dis Sci 53 1 (2008) 140
15. Humar A., Gregson D., Caliendo A.M., McGeer A., Malkan G., Krajden M., et al. Clinical utility of quantitative cytomegalovirus viral load determination for predicting cytomegalovirus disease in liver transplant recipients. Transplantation 68 9 (1999) 1305-1311
16. Mendez J., Espy M., Smith T.F., Wilson J., Wiesner R., and Paya C.V. Clinical significance of viral load in the diagnosis of cytomegalovirus disease after liver transplantation. Transplantation 65 11 (1998) 1477-1481
17. Roberts T.C., Brennan D.C., Buller R.S., Gaudreault-Keener M., Schnitzler M.A., Sternhell K.E., et al. Quantitative polymerase chain reaction to predict occurrence of symptomatic cytomegalovirus infection and assess response to ganciclovir therapy in renal transplant recipients. J Infect Dis 178 3 (1998) 626-635
18. Einsele H., Ehninger G., Steidle M., Vallbracht A., Muller M., Schmidt H., et al. Polymerase chain reaction to evaluate antiviral therapy for cytomegalovirus disease. Lancet 338 8776 (1991) 1170-1172