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Volumn 878, Issue 19, 2010, Pages 1623-1628
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The novel sensitive and high throughput determination of cefepime in mouse plasma by SCX-LC/MS/MS method following off-line μElution 96-well solid-phase extraction to support systemic antibiotic programs
a
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Author keywords
Elution SPE; Cefepime; LC MS MS; Mouse plasma; Pharmacokinetics; SCX
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Indexed keywords
96-WELL;
CEFEPIME;
CEFTAZIDIME;
CONCENTRATION LEVELS;
HIGH THROUGHPUT;
INTERNAL STANDARDS;
INTRA-ASSAY PRECISION;
LC/MS/MS;
LINEAR RANGE;
LOWER LIMIT OF QUANTITATIONS;
MOUSE PLASMA;
SOLID-PHASE EXTRACTION;
STRONG CATION EXCHANGES;
TANDEM MASS SPECTROMETRY;
CUSTOMER SATISFACTION;
LIQUID CHROMATOGRAPHY;
MASS SPECTROMETRY;
PHARMACOKINETICS;
PLASMAS;
THROUGHPUT;
TOTAL QUALITY MANAGEMENT;
EXTRACTION;
ANTIBIOTIC AGENT;
CEFEPIME;
CEFTAZIDIME;
ACCURACY;
ANIMAL EXPERIMENT;
AREA UNDER THE CURVE;
ARTICLE;
COMPARTMENT MODEL;
CONTROLLED STUDY;
DISTRIBUTION VOLUME;
DRUG BLOOD LEVEL;
DRUG CLEARANCE;
DRUG HALF LIFE;
DRUG STRUCTURE;
ELUTION;
FEMALE;
HIGH THROUGHPUT SCREENING;
ION EXCHANGE CHROMATOGRAPHY;
LIQUID CHROMATOGRAPHY;
MAXIMUM PLASMA CONCENTRATION;
MOUSE;
NONHUMAN;
PLASMA CONCENTRATION-TIME CURVE;
PRIORITY JOURNAL;
QUALITY CONTROL;
SENSITIVITY AND SPECIFICITY;
SINGLE DRUG DOSE;
SOLID PHASE EXTRACTION;
TANDEM MASS SPECTROMETRY;
VALIDATION PROCESS;
ANIMALS;
CEPHALOSPORINS;
CHROMATOGRAPHY, GEL;
FEMALE;
LINEAR MODELS;
MICE;
REPRODUCIBILITY OF RESULTS;
SENSITIVITY AND SPECIFICITY;
SOLID PHASE EXTRACTION;
TANDEM MASS SPECTROMETRY;
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EID: 77952106355
PISSN: 15700232
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jchromb.2010.03.045 Document Type: Article |
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Times cited : (19)
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References (14)
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