Improving the relaxivity by dimerizing Gd-AAZTA: Insights for enhancing the sensitivity of MRI contrast agents

Inorganic Chemistry Communications

Volumn 13, Issue 5, 2010, Pages 663-665

  Gianolio, Eliana ^a   Ramalingam, Kondareddiar ^b   Song, Bo ^b   Kalman, Ferenc ^a   Aime, Silvio ^a   Swenson, Rolf ^b  

^a UNIVERSITY OF TURIN   (Italy)

^b Bracco Research USA   (United States)

Author keywords

Gadolinium chelate; MRI imaging; Relaxivity

Indexed keywords

EID: 77952102140     PISSN: 13877003     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.inoche.2010.03.014     Document Type: Article

References (16)

1. Aime S., Calabi L., Cavallotti C., Gianolio E., Giovenzana G.B., Losi P., Maiocchi A., Palmisano G., and Sisti M. Inorg. Chem. 43 (2004) 7588-7590
2. Baranyai Z., Uggeri F., Giovenzana G.B., Nyei A.B., Brucher E., and Aime S. Chem. Eur. J. 15 (2009) 1696-1705
3. Gianolio E., Giovenzana G.B., Longo D., Longo I., Menegotto I., and Aime S. Chem. Eur. J. 13 (2007) 5785-5797
4. Gianolio E., Giovenzana G.B., Ciampa A., Lanzardo S., Imperio D., and Aime S. Chem. Med. Chem. 3 (2008) 60-62
5. Elemento E.M., Parker D., Aime S., Gianolio E., and Lattuada L. Org. Biomol. Chem. 7 (2009) 1120-1131
6. Gugliotta G., Botta M., Giovenzana G.B., and Tei L. Bioorg. Med. Chem. Lett. 19 (2009) 3442-3444
7. Tweedle M., Kang S., Ratsep P., Enswiler J., Kumar K., Pillai R.K., Ranganathan R., Shukla R., and Zhang X. New Nonionic Macrocyclic Gadolinium Chelates. In: Rink P.A., and Muller R.N. (Eds). New Developments in Contrast Agent Research, Proceedings of the 3rd Special Topic Seminar of the European Magnetic Resonance Forum (September 1992) (1993), European Magnetic Resonance Forum Foundation C/O Univ. Mons, Belgium 59-65
8. Powell D.H., Dhubhghaill O.M.N., Pubanz D., Helm L., Lebedev Y.S., Schlaepfer W., and Merbach A.E. J. Am. Chem.Soc. 118 (1996) 9333
9. Toth E., Vauthey S., Pubanz D., and Merbach A.E. Inorg. Chem. 35 (1996) 3375-3379
10. Lee T.M., Cheng T.H., Ou M.H., Chang C.A., Liu C.G., and Wang Y.M. Magn. Reson. Chem. 42 (2004) 329-336
11. Costa J., Toth E., Helm L., and Merbach A.E. Inorg. Chem. 44 (2005) 4747-4755
12. Rudovsky J., Botta M., Hermann P., Koridze A., and Aime S. Dalton Trans. (2006) 2323-2333
13. Blombergen N.J. Chem. Phys. 27 (1957) 572-573
14. Solomon I. Phys. Rev. 99 (1955) 559-565
15. Freed J.H.J. Chem. Phys. 68 (1978) 4034-4037
16. Swift T.J., and Connick R.E.J. Chem. Phys. 37 (1962) 307-320