The potential role of kinesin and dynein in golgi scattering and cytoplasmic vacuole formation during acute experimental pancreatitis

Cell Research

Volumn 20, Issue 5, 2010, Pages 599-602

  Weber, Ina A ^a   Buchwalow, Igor ^b   Hahn, Daniela ^a   Domschke, Wolfram ^a   Lerch, Markus M ^c   Schnekenburger, Jürgen ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^c UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CERULETIDE; DYNEIN ADENOSINE TRIPHOSPHATASE; KINESIN;

ACUTE DISEASE; ANIMAL; CHEMICALLY INDUCED DISORDER; CYTOPLASM; GOLGI COMPLEX; LETTER; MALE; METABOLISM; PANCREATITIS; PATHOLOGY; RAT; WISTAR RAT;

ACUTE DISEASE; ANIMALS; CAERULEIN; CYTOPLASM; DYNEINS; GOLGI APPARATUS; KINESIN; MALE; PANCREATITIS; RATS; RATS, WISTAR;

EID: 77952096316     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2010.42     Document Type: Letter

References (13)

1. Saluja AK, Lerch MM, Phillips PA, Dudeja V. Why does pancreatic overstimulation cause pancreatitis? Annu Rev Physiol 2007;69:249-269. (Pubitemid 46457643)
2. Jungermann J, Lerch MM, Weidenbach H, Lutz MP, Krüger B, Adler G. Disassembly of rat pancreatic acinar cell cytoskeleton during supramaximal secretagogue stimulation. Am J Physiol 1995; (2 Pt 1) :G328-G338.
3. Hehnly H, Stamnes M. Regulating cytoskeleton-based vesicle motility. FEBS Lett 2007;581:2112-2118. (Pubitemid 46709903)
4. Schnekenburger J, Weber IA, Hahn D, et al. The role of kinesin, dynein and microtubules in pancreatic secretion. Cell Mol Life Sci 2009;66:2525-2537.
5. Williams JA, Lee M. Microtubules and pancreatic amylase release by mouse pancreas in vitro. J Cell Biol 1976;71:795-806
6. Ueda T, Takeyama Y, Kaneda K, Adachi M, Ohyanagi H, Saitoh Y. Protective effect of a microtubule stabilizer taxol on caerulein-induced acute pancreatitis in rat. J Clin Invest 1992;89:234-243.
7. Schnekenburger J, Schick V, Kruger B, et al. The calcium binding protein S100A9 is essential for pancreatic leukocyte infltration and induces disruption of cell-cell contacts. J Cell Physiol 2008;216:558-567. (Pubitemid 351898485)
8. Pavelka M, Ellinger A. Effect of colchicine on the Golgi complex of rat pancreatic acinar cells. J Cell Biol 1983;97:737-748 (Pubitemid 13007192)
9. Palade G. Intracellular aspects of the process of protein synthesis. Science 1975;189:347-358.
10. Allan VJ, Thompson HM, McNiven MA. Motoring around the Golgi. Nat Cell Biol 2002;4: E236-E242.
11. Sato-Yoshitake R, Yorifuji H, Inagaki M, Hirokawa N. The phosphorylation of kinesin regulates its binding to synaptic vesicles. J Biol Chem 1992;267:23930-23936. (Pubitemid 23088206)
12. Vaughan PS, Leszyk JD, Vaughan KT. Cytoplasmic dynein intermediate chain phosphorylation regulates binding to dynactin. J Biol Chem 2001;276:26171-26179. (Pubitemid 37412830)
13. Van Acker GJ, Weiss E, Steer ML, Perides G. Cause-effect relationships between zymogen activation and other early events in secretagogue-induced acute pancreatitis. Am J Physiol 2007;292: G1738-G1746. (Pubitemid 47080596)