Alcohol-induced changes in the brain as assessed by MRI and CT

European Radiology

Volumn 20, Issue 6, 2010, Pages 1492-1501

  Geibprasert, Sasikhan ^a   Gallucci, Massimo ^b   Krings, Timo ^c  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b SAN SALVATORE HOSPITAL   (Italy)

^c TORONTO WESTERN HOSPITAL   (Canada)

Author keywords

Alcohol; Atrophy; Brain; Marchiafava Bignami disease; Osmotic myelinolysis; Wernicke encephalopathy

Indexed keywords

ALCOHOL; ETHYLENE GLYCOL; METHANOL; THIAMINE;

ALCOHOL ABUSE; ALCOHOL INTOXICATION; ALCOHOL WITHDRAWAL; BRAIN ATROPHY; BRAIN TOXICITY; CENTRAL PONTINE MYELINOLYSIS; COMA; COMPUTER ASSISTED TOMOGRAPHY; DEATH; DISSEMINATED INTRAVASCULAR CLOTTING; EARLY DIAGNOSIS; HEPATIC ENCEPHALOPATHY; HUMAN; IMAGE ANALYSIS; MALNUTRITION; MARCHIAFAVA BIGNAMI DISEASE; METHANOL POISONING; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; WERNICKE ENCEPHALOPATHY;

ALCOHOLIC INTOXICATION; BRAIN; BRAIN DISEASES; ETHANOL; HUMANS; MAGNETIC RESONANCE IMAGING; METHANOL; TOMOGRAPHY, X-RAY COMPUTED;

EID: 77952091605     PISSN: 09387994     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00330-009-1668-z     Document Type: Review

References (70)

1. World Health Organization (WHO) (2004) Global status report: alcohol policy. WHO, Geneva
2. RF Anton 2008 Naltrexone for the management of alcohol dependence N Engl J Med 359 715 721 10.1056/NEJMct0801733 1:CAS:528:DC%2BD1cXhtVSht7%2FP 18703474
3. C Harper 2007 The neurotoxicity of alcohol Hum Exp Toxicol 26 251 257 10.1177/0960327107070499 1:CAS:528:DC%2BD2sXkslWhs7g%3D 17439928 (Pubitemid 46456803)
4. MV Spampinato M Castillo R Rojas E Palacios L Frascheri F Descartes 2005 Magnetic resonance imaging findings in substance abuse: alcohol and alcoholism and syndromes associated with alcohol abuse Top Magn Reson Imaging 16 223 230 10.1097/01.rmr.0000192175.26243.a7 16340646 (Pubitemid 43361871)
5. A Rovira J Alonso J Cordoba 2008 MR imaging findings in hepatic encephalopathy AJNR Am J Neuroradiol 29 1612 1621 10.3174/ajnr.A1139 1:STN:280:DC%2BD1cnkvVCmsQ%3D%3D 18583413
6. K Mann I Agartz C Harper, et al. 2001 Neuroimaging in alcoholism: ethanol and brain damage Alcohol Clin Exp Res 25 Suppl ISBRA 104S 109S 1:CAS:528:DC%2BD3MXktleru7Y%3D 11391058
7. AJ Bartsch G Homola A Biller, et al. 2007 Manifestations of early brain recovery associated with abstinence from alcoholism Brain 130 36 47 10.1093/brain/awl303 17178742 (Pubitemid 46026221)
8. JJ Kril CG Harper 1989 Neuronal counts from four cortical regions of alcoholic brains Acta Neuropathol 79 200 204 10.1007/BF00294379 1:STN:280:DyaK3c%2Fos1ajuw%3D%3D 2596268
9. M Bendszus HG Weijers G Wiesbeck, et al. 2001 Sequential MR imaging and proton MR spectroscopy in patients who underwent recent detoxification for chronic alcoholism: correlation with clinical and neuropsychological data AJNR Am J Neuroradiol 22 1926 1932 1:STN:280:DC%2BD3Mnos1ygtw%3D%3D 11733327
10. MD De Bellis E Van Voorhees SR Hooper, et al. 2008 Diffusion tensor measures of the corpus callosum in adolescents with adolescent onset alcohol use disorders Alcohol Clin Exp Res 32 395 404 10.1111/j.1530-0277.2007.00603.x 18241319 (Pubitemid 351301002)
11. A Pfefferbaum M Rosenbloom T Rohlfing EV Sullivan 2009 Degradation of association and projection white matter systems in alcoholism detected with quantitative fiber tracking Biol Psychiatry 65 680 690 10.1016/j.biopsych.2008. 10.039 1:CAS:528:DC%2BD1MXjslKltb4%3D 19103436
12. E Lee DP Jang JJ Kim, et al. 2007 Alteration of brain metabolites in young alcoholics without structural changes Neuroreport 18 1511 1514 10.1097/WNR.0b013e3282ef7625 1:CAS:528:DC%2BD2sXpt1Kjsr8%3D 17712285 (Pubitemid 47295956)
13. BC Schweinsburg MJ Taylor OM Alhassoon, et al. 2001 Chemical pathology in brain white matter of recently detoxified alcoholics: a 1H magnetic resonance spectroscopy investigation of alcohol-associated frontal lobe injury Alcohol Clin Exp Res 25 924 934 10.1111/j.1530-0277.2001.tb02299.x 1:CAS:528: DC%2BD3MXltFemsbg%3D 11410730
14. G Ende H Welzel S Walter, et al. 2005 Monitoring the effects of chronic alcohol consumption and abstinence on brain metabolism: a longitudinal proton magnetic resonance spectroscopy study Biol Psychiatry 58 974 980 10.1016/j.biopsych.2005.05.038 1:CAS:528:DC%2BD2MXhtlaisLnI 16084857 (Pubitemid 41790708)
15. ZJ Ke X Wang Z Fan J Luo 2009 Ethanol promotes thiamine deficiency-induced neuronal death: involvement of double-stranded RNA-activated protein kinase Alcohol Clin Exp Res 33 1097 1103 10.1111/j.1530-0277.2009.00931. x 1:CAS:528:DC%2BD1MXosVygsbw%3D 19382901
16. C Harper 1979 Wernicke's encephalopathy: a more common disease than realised. A neuropathological study of 51 cases J Neurol Neurosurg Psychiatry 42 226 231 10.1136/jnnp.42.3.226 1:STN:280:DyaE1M7nsVKqtw%3D%3D 438830
17. A Torvik CF Lindboe S Rogde 1982 Brain lesions in alcoholics. A neuropathological study with clinical correlations J Neurol Sci 56 233 248 10.1016/0022-510X(82)90145-9 1:STN:280:DyaL3s%2FosV2nsQ%3D%3D 7175549 (Pubitemid 12002346)
18. G Opdenakker G Gelin D De Surgeloose Y Palmers 1999 Wernicke encephalopathy: MR findings in two patients Eur Radiol 9 1620 1624 10.1007/s003300050896 1:STN:280:DyaK1Mvlslamsw%3D%3D 10525877
19. EV Sullivan L Marsh 2003 Hippocampal volume deficits in alcoholic Korsakoff's syndrome Neurology 61 1716 1719 14694035
20. AS Hazell KG Todd RF Butterworth 1998 Mechanisms of neuronal cell death in Wernicke's encephalopathy Metab Brain Dis 13 97 122 10.1023/A:1020657129593 1:CAS:528:DyaK1cXltlChsLk%3D 9699919 (Pubitemid 28350746)
21. M Victor RD Adams GH Collins 1971 The Wernicke-Korsakoff syndrome. A clinical and pathological study of 245 patients, 82 with post-mortem examinations Contemp Neurol Ser 7 1 206 1:STN:280:DyaE3s3htFWrsg%3D%3D 5162155
22. M Gallucci A Bozzao A Splendiani C Masciocchi R Passariello 1990 Wernicke encephalopathy: MR findings in five patients AJR Am J Roentgenol 155 1309 1314 1:STN:280:DyaK3M%2FltFWiuw%3D%3D 2122685
23. S Weidauer M Nichtweiss H Lanfermann FE Zanella 2003 Wernicke encephalopathy: MR findings and clinical presentation Eur Radiol 13 1001 1009 12695821
24. T Moritani WR Smoker Y Sato Y Numaguchi PL Westesson 2005 Diffusion-weighted imaging of acute excitotoxic brain injury AJNR Am J Neuroradiol 26 216 228 15709116
25. CA Rugilo MC Roca MC Zurru EM Gatto 2003 Diffusion abnormalities and Wernicke encephalopathy Neurology 60 727 728 1:STN:280:DC%2BD3s%2FptlKqtA%3D%3D 12607546
26. ML White Y Zhang LG Andrew WL Hadley 2005 MR imaging with diffusion-weighted imaging in acute and chronic Wernicke encephalopathy AJNR Am J Neuroradiol 26 2306 2310 16219837
27. P D'Aprile MA Gentile A Carella 1994 Enhanced MR in the acute phase of Wernicke encephalopathy AJNR Am J Neuroradiol 15 591 593 8197963
28. G Schroth W Wichmann A Valavanis 1991 Blood-brain-barrier disruption in acute Wernicke encephalopathy: MR findings J Comput Assist Tomogr 15 1059 1061 10.1097/00004728-199111000-00034 1:STN:280:DyaK38%2Fkt12gtQ%3D%3D 1939760
29. ME Shogry JT Curnes 1994 Mamillary body enhancement on MR as the only sign of acute Wernicke encephalopathy AJNR Am J Neuroradiol 15 172 174 1:STN:280:DyaK2c7ovFCmtQ%3D%3D 8141051
30. G Zuccoli M Gallucci J Capellades, et al. 2007 Wernicke encephalopathy: MR findings at clinical presentation in twenty-six alcoholic and nonalcoholic patients AJNR Am J Neuroradiol 28 1328 1331 10.3174/ajnr.A0544 1:STN:280:DC%2BD2svotFGisw%3D%3D 17698536 (Pubitemid 47309667)
31. G Zuccoli D Santa Cruz M Bertolini, et al. 2009 MR imaging findings in 56 patients with Wernicke encephalopathy: nonalcoholics may differ from alcoholics AJNR Am J Neuroradiol 30 171 176 10.3174/ajnr.A1280 1:STN:280: DC%2BD1M%2FmsFehtA%3D%3D 18945789
32. H Hofer 1958 Zur Morphologie der circumventrikularen Organe des Zwischenhirns der Saugetiere Deutsch Zool Ges Verhandl 8 202 251
33. B Yoon YS Shim SW Chung 2008 Central pontine and extrapontine myelinolysis after alcohol withdrawal Alcohol Alcohol 43 647 649 1:CAS:528:DC%2BD1cXht12gtLbO 18678596
34. K Hagiwara Y Okada N Shida Y Yamashita 2008 Extensive central and extrapontine myelinolysis in a case of chronic alcoholism without hyponatremia: a case report with analysis of serial MR findings Intern Med 47 431 435 10.2169/internalmedicine.47.0634 18310977 (Pubitemid 351663697)
35. TM Koci F Chiang P Chow, et al. 1990 Thalamic extrapontine lesions in central pontine myelinolysis AJNR Am J Neuroradiol 11 1229 1233 1:STN:280:DyaK3M%2Fns1Whtg%3D%3D 2124066
36. KA Ruzek NG Campeau GM Miller 2004 Early diagnosis of central pontine myelinolysis with diffusion-weighted imaging AJNR Am J Neuroradiol 25 210 213 14970019
37. A Uchino T Yuzuriha M Murakami, et al. 2003 Magnetic resonance imaging of sequelae of central pontine myelinolysis in chronic alcohol abusers Neuroradiology 45 877 880 10.1007/s00234-003-1095-9 14508621 (Pubitemid 38072258)
38. J Helenius T Tatlisumak L Soinne L Valanne M Kaste 2001 Marchiafava-Bignami disease: two cases with favourable outcome Eur J Neurol 8 269 272 10.1046/j.1468-1331.2001.00212.x 1:STN:280:DC%2BD3MzntVyktA%3D%3D 11328337 (Pubitemid 32476627)
39. A Arbelaez A Pajon M Castillo 2003 Acute Marchiafava-Bignami disease: MR findings in two patients AJNR Am J Neuroradiol 24 1955 1957 14625216
40. KH Chang SH Cha MH Han SH Park DL Nah JH Hong 1992 Marchiafava-Bignami disease: serial changes in corpus callosum on MRI Neuroradiology 34 480 482 10.1007/BF00598954 1:STN:280:DyaK3s%2FmtlOqug%3D%3D 1436454
41. K Johkura M Naito T Naka 2005 Cortical involvement in Marchiafava-Bignami disease AJNR Am J Neuroradiol 26 670 673 15760886
42. SA Friese M Bitzer D Freudenstein K Voigt W Kuker 2000 Classification of acquired lesions of the corpus callosum with MRI Neuroradiology 42 795 802 10.1007/s002340000430 1:STN:280:DC%2BD3M7jtVeqtQ%3D%3D 11151683
43. EC Bourekas K Varakis D Bruns, et al. 2002 Lesions of the corpus callosum: MR imaging and differential considerations in adults and children AJR Am J Roentgenol 179 251 257 12076946
44. K Yamashita S Kobayashi S Yamaguchi H Koide K Nishi 1997 Reversible corpus callosum lesions in a patient with Marchiafava-Bignami disease: serial changes on MRI Eur Neurol 37 192 193 10.1159/000117435 1:STN:280: DyaK2s3otlymtQ%3D%3D 9137933
45. M Echevarria 1881 On alcoholic epilepsy J Med Sci 26 489
46. FN Brennan JA Lyttle 1987 Alcohol and seizures: a review J R Soc Med 80 571 573 1:STN:280:DyaL1c%2Fmt1Gnsw%3D%3D 3316652
47. EV Sullivan L Marsh DH Mathalon KO Lim A Pfefferbaum 1996 Relationship between alcohol withdrawal seizures and temporal lobe white matter volume deficits Alcohol Clin Exp Res 20 348 354 10.1111/j.1530-0277.1996.tb01651.x 1:STN:280:DyaK283nvFyqtg%3D%3D 8730229 (Pubitemid 26117909)
48. LJ Chandler E Carpenter-Hyland AW Hendricson, et al. 2006 Structural and functional modifications in glutamateric synapses following prolonged ethanol exposure Alcohol Clin Exp Res 30 368 376 10.1111/j.1530-0277.2006.00041.x 1:CAS:528:DC%2BD28XitFygur4%3D 16441286 (Pubitemid 43341387)
49. TL Ripley MA Whittington AR Butterworth HJ Little 1996 Ethanol withdrawal hyperexcitability in vivo and in isolated mouse hippocampal slices Alcohol Alcohol 31 347 357 1:CAS:528:DyaK28XlvF2ku7g%3D 8879281
50. M Wojnar Z Bizon D Wasilewski 1999 Assessment of the role of kindling in the pathogenesis of alcohol withdrawal seizures and delirium tremens Alcohol Clin Exp Res 23 204 208 1:STN:280:DyaK1M7mslSktA%3D%3D 10069546
51. RF Butterworth 2003 Hepatic encephalopathy Alcohol Res Health 27 240 246 15535452
52. SP Av 2007 Hepatic encephalopathy: pathophysiology and advances in therapy Trop Gastroenterol 28 4 10 17896602
53. D Krieger S Krieger O Jansen P Gass L Theilmann H Lichtnecker 1995 Manganese and chronic hepatic encephalopathy Lancet 346 270 274 10.1016/S0140-6736(95)92164-8 1:CAS:528:DyaK2MXntlKhtL8%3D 7630246
54. A Geissler G Lock R Frund, et al. 1997 Cerebral abnormalities in patients with cirrhosis detected by proton magnetic resonance spectroscopy and magnetic resonance imaging Hepatology 25 48 54 10.1002/hep.510250109 1:STN:280: DyaK2s7jvVagtQ%3D%3D 8985263
55. D Haussinger J Laubenberger S vom Dahl, et al. 1994 Proton magnetic resonance spectroscopy studies on human brain myo-inositol in hypo-osmolarity and hepatic encephalopathy Gastroenterology 107 1475 1480 1:STN:280: DyaK2M%2FhtFejsQ%3D%3D 7926510
56. PE Sijens H Alkefaji RJ Lunsing, et al. 2008 Quantitative multivoxel 1H MR spectroscopy of the brain in children with acute liver failure Eur Radiol 18 2601 2609 10.1007/s00330-008-1049-z 18493780
57. L Amitrano MA Guardascione V Brancaccio A Balzano 2002 Coagulation disorders in liver disease Semin Liver Dis 22 83 96 10.1055/s-2002-23205 1:CAS:528:DC%2BD38XislCgtbY%3D 11928081
58. M Blanco R Casado F Vazquez JM Pumar 2006 CT and MR imaging findings in methanol intoxication AJNR Am J Neuroradiol 27 452 454 1:STN:280: DC%2BD28%2Fps1CmsA%3D%3D 16484428
59. KE McMartin JJ Ambre TR Tephly 1980 Methanol poisoning in human subjects. Role for formic acid accumulation in the metabolic acidosis Am J Med 68 414 418 10.1016/0002-9343(80)90113-8 1:STN:280:DyaL3c7ltV2gtg%3D%3D 7361809
60. F Onder S Ilker T Kansu T Tatar G Kural 1998 Acute blindness and putaminal necrosis in methanol intoxication Int Ophthalmol 22 81 84 10.1023/A:1006173526927 10472766 (Pubitemid 29396301)
61. BV Mittal AP Desai KR Khade 1991 Methyl alcohol poisoning: an autopsy study of 28 cases J Postgrad Med 37 9 13 1:STN:280:DyaK38%2FksFKitA%3D%3D 1941700
62. PT Phang L Passerini B Mielke R Berendt EG King 1988 Brain hemorrhage associated with methanol poisoning Crit Care Med 16 137 140 10.1097/00003246- 198802000-00008 1:STN:280:DyaL1c7js1Gguw%3D%3D 3342624
63. S Sefidbakht AR Rasekhi K Kamali, et al. 2007 Methanol poisoning: acute MR and CT findings in nine patients Neuroradiology 49 427 435 10.1007/s00234-007-0210-8 1:STN:280:DC%2BD2s3ls1Smsw%3D%3D 17294234 (Pubitemid 46951328)
64. K Kuteifan H Oesterle T Tajahmady AM Gutbub G Laplatte 1998 Necrosis and haemorrhage of the putamen in methanol poisoning shown on MRI Neuroradiology 40 158 160 10.1007/s002340050558 1:STN:280:DyaK1c3it1ejsQ%3D%3D 9561519 (Pubitemid 28438825)
65. D Rubinstein E Escott JP Kelly 1995 Methanol intoxication with putaminal and white matter necrosis: MR and CT findings AJNR Am J Neuroradiol 16 1492 1494 1:STN:280:DyaK28%2FivF2itQ%3D%3D 7484638
66. S Deniz C Oppenheim S Lehericy, et al. 2000 Diffusion-weighted magnetic resonance imaging in a case of methanol intoxication Neurotoxicology 21 405 408 1:STN:280:DC%2BD3M%2Fit1ejuw%3D%3D 10894130
67. A Server KE Hovda PH Nakstad D Jacobsen R Dullerud M Haakonsen 2003 Conventional and diffusion-weighted MRI in the evaluation of methanol poisoning Acta Radiol 44 691 695 1:STN:280:DC%2BD3srjs1eitg%3D%3D 14616218
68. GP Daubert A Katiyar J Wilson L Baltarowich 2006 Encephalopathy and peripheral neuropathy following diethylene glycol ingestion Neurology 66 782 783 10.1212/01.wnl.0000205134.08259.32 16534135
69. YD Rollins CM Filley JT McNutt S Chahal BK Kleinschmidt-DeMasters 2002 Fulminant ascending paralysis as a delayed sequela of diethylene glycol (Sterno) ingestion Neurology 59 1460 1463 1:STN:280:DC%2BD38nmslKktA%3D%3D 12427908
70. MJ Hasbani LH Sansing J Perrone AK Asbury SJ Bird 2005 Encephalopathy and peripheral neuropathy following diethylene glycol ingestion Neurology 64 1273 1275 1:STN:280:DC%2BD2M7ptFeqsg%3D%3D 15824363