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Volumn 85, Issue 1, 2010, Pages 76-80

Mechanisms of the embryo's response to embryopathic stressors: A focus on p53

Author keywords

Developmental toxicants; Embryo; Inborn anomalies; P53; Teratogens

Indexed keywords

BENZO[A]PYRENE; CLADRIBINE; CYCLOPHOSPHAMIDE; PROTEIN P53;

EID: 77952091093     PISSN: 01650378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jri.2010.01.003     Document Type: Review
Times cited : (13)

References (39)
  • 2
    • 34547935761 scopus 로고    scopus 로고
    • Living with p53, dying of p53
    • Aylon Y., Oren M. Living with p53, dying of p53. Cell 2007, 130:597-600.
    • (2007) Cell , vol.130 , pp. 597-600
    • Aylon, Y.1    Oren, M.2
  • 4
    • 33747873330 scopus 로고    scopus 로고
    • Variable in vivo embryoprotective role for ataxia-telangiectasia-mutated against constitutive and phenytoin-enhanced oxidative stress in atm knockout mice
    • Bhuller Y., Jeng W., Wells P.G. Variable in vivo embryoprotective role for ataxia-telangiectasia-mutated against constitutive and phenytoin-enhanced oxidative stress in atm knockout mice. Toxicol. Sci. 2006, 93:146-155.
    • (2006) Toxicol. Sci. , vol.93 , pp. 146-155
    • Bhuller, Y.1    Jeng, W.2    Wells, P.G.3
  • 5
    • 33747894202 scopus 로고    scopus 로고
    • A developmental role for ataxia-telangiectasia mutated in protecting the embryo from spontaneous and phenytoin-enhanced embryopathies in culture
    • Bhuller Y., Wells P.G. A developmental role for ataxia-telangiectasia mutated in protecting the embryo from spontaneous and phenytoin-enhanced embryopathies in culture. Toxicol. Sci. 2006, 93:156-163.
    • (2006) Toxicol. Sci. , vol.93 , pp. 156-163
    • Bhuller, Y.1    Wells, P.G.2
  • 6
    • 0032427628 scopus 로고    scopus 로고
    • The role of ATM in DNA damage responses and cancer
    • Canman C.E., Lim D.S. The role of ATM in DNA damage responses and cancer. Oncogene 1998, 17:3301-3308.
    • (1998) Oncogene , vol.17 , pp. 3301-3308
    • Canman, C.E.1    Lim, D.S.2
  • 8
    • 53049109167 scopus 로고    scopus 로고
    • Ionizing radiation-induced gene modulations, cytokine content changes and telomere shortening in mouse fetuses exhibiting forelimb defects
    • Derradji H., Bekaert S., De Meyer T., Jacquet P., Abou-El-Ardat K., Ghardi M., Arlette M., Baatout S. Ionizing radiation-induced gene modulations, cytokine content changes and telomere shortening in mouse fetuses exhibiting forelimb defects. Dev. Biol. 2008, 322:302-313.
    • (2008) Dev. Biol. , vol.322 , pp. 302-313
    • Derradji, H.1    Bekaert, S.2    De Meyer, T.3    Jacquet, P.4    Abou-El-Ardat, K.5    Ghardi, M.6    Arlette, M.7    Baatout, S.8
  • 10
    • 8144227769 scopus 로고    scopus 로고
    • Apoptosis: the sculptor of development
    • Doseff A.I. Apoptosis: the sculptor of development. Stem Cells Dev. 2004, 13:473-483.
    • (2004) Stem Cells Dev. , vol.13 , pp. 473-483
    • Doseff, A.I.1
  • 11
    • 0022863986 scopus 로고
    • Hyperthermia as a teratogen: a review of experimental studies and their clinical significance
    • Edwards M.J. Hyperthermia as a teratogen: a review of experimental studies and their clinical significance. Teratog. Carcinog. Mutagen. 1986, 6:563-582.
    • (1986) Teratog. Carcinog. Mutagen. , vol.6 , pp. 563-582
    • Edwards, M.J.1
  • 12
    • 0017058778 scopus 로고
    • The multifactorial/threshold concept-uses and misuses
    • Fraser F.C. The multifactorial/threshold concept-uses and misuses. Teratology 1976, 14:267-280.
    • (1976) Teratology , vol.14 , pp. 267-280
    • Fraser, F.C.1
  • 13
    • 0034669944 scopus 로고    scopus 로고
    • Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria
    • Genini D., Adachi S., Chao Q., Rose D.W., Carrera C.J., Cottam H.B., Carson D.A., Leoni L.M. Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria. Blood 2000, 96:3537-3543.
    • (2000) Blood , vol.96 , pp. 3537-3543
    • Genini, D.1    Adachi, S.2    Chao, Q.3    Rose, D.W.4    Carrera, C.J.5    Cottam, H.B.6    Carson, D.A.7    Leoni, L.M.8
  • 14
    • 0030898436 scopus 로고    scopus 로고
    • Transgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiation-induced activation during embryogenesis
    • Gottlieb E., Haffner R., King A., Asher G., Gruss P., Lonai P., Oren M. Transgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiation-induced activation during embryogenesis. EMBO J. 1997, 16:1381-1390.
    • (1997) EMBO J. , vol.16 , pp. 1381-1390
    • Gottlieb, E.1    Haffner, R.2    King, A.3    Asher, G.4    Gruss, P.5    Lonai, P.6    Oren, M.7
  • 15
    • 0032544268 scopus 로고    scopus 로고
    • Apoptotic pathways: the roads to ruin
    • Green D.R. Apoptotic pathways: the roads to ruin. Cell 1998, 94:695-698.
    • (1998) Cell , vol.94 , pp. 695-698
    • Green, D.R.1
  • 16
    • 33847271089 scopus 로고    scopus 로고
    • Coping with stress: multiple ways to activate p53
    • Horn H.F., Vousden K.H. Coping with stress: multiple ways to activate p53. Oncogene 2007, 26:1306-1316.
    • (2007) Oncogene , vol.26 , pp. 1306-1316
    • Horn, H.F.1    Vousden, K.H.2
  • 19
    • 0035139637 scopus 로고    scopus 로고
    • Threshold effect for teratogenic risk of radiation depends on dose-rate and p53-dependent apoptosis
    • Kato F., Ootsuyama A., Nomoto S., Kondo S., Norimura T. Threshold effect for teratogenic risk of radiation depends on dose-rate and p53-dependent apoptosis. Int. J. Radiat. Biol. 2001, 77:13-19.
    • (2001) Int. J. Radiat. Biol. , vol.77 , pp. 13-19
    • Kato, F.1    Ootsuyama, A.2    Nomoto, S.3    Kondo, S.4    Norimura, T.5
  • 20
    • 5044225427 scopus 로고    scopus 로고
    • Antisense evidence for nuclear factor-kappaB-dependent embryopathies initiated by phenytoin-enhanced oxidative stress
    • Kennedy J.C., Memet S., Wells P.G. Antisense evidence for nuclear factor-kappaB-dependent embryopathies initiated by phenytoin-enhanced oxidative stress. Mol. Pharmacol. 2004, 66:404-412.
    • (2004) Mol. Pharmacol. , vol.66 , pp. 404-412
    • Kennedy, J.C.1    Memet, S.2    Wells, P.G.3
  • 21
    • 0027109075 scopus 로고
    • Cancer. p53, guardian of the genome
    • Lane D.P. Cancer. p53, guardian of the genome. Nature 1992, 358:15-16.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 22
    • 61949171744 scopus 로고    scopus 로고
    • Differential involvement of reactive oxygen species and nucleoside transporters in cytotoxicity induced by two adenosine analogues in human prostate cancer cells
    • Minelli A., Bellezza I., Tucci A., Rambotti M.G., Conte C., Culig Z. Differential involvement of reactive oxygen species and nucleoside transporters in cytotoxicity induced by two adenosine analogues in human prostate cancer cells. Prostate 2009, 69:538-547.
    • (2009) Prostate , vol.69 , pp. 538-547
    • Minelli, A.1    Bellezza, I.2    Tucci, A.3    Rambotti, M.G.4    Conte, C.5    Culig, Z.6
  • 23
    • 0022390040 scopus 로고
    • Cyclophosphamide teratogenesis: a review
    • Mirkes P.E. Cyclophosphamide teratogenesis: a review. Teratog. Carcinog. Mutagen. 1985, 5:75-88.
    • (1985) Teratog. Carcinog. Mutagen. , vol.5 , pp. 75-88
    • Mirkes, P.E.1
  • 24
    • 38449116409 scopus 로고    scopus 로고
    • Cell death in normal and abnormal development
    • Mirkes P.E. Cell death in normal and abnormal development. Congenit. Anom. (Kyoto) 2008, 48:7-17.
    • (2008) Congenit. Anom. (Kyoto) , vol.48 , pp. 7-17
    • Mirkes, P.E.1
  • 25
    • 0031669515 scopus 로고    scopus 로고
    • The role of p53 and cell death by apoptosis and necrosis in 4-hydroperoxycyclophosphamide-induced limb malformations
    • Moallem S.A., Hales B.F. The role of p53 and cell death by apoptosis and necrosis in 4-hydroperoxycyclophosphamide-induced limb malformations. Development 1998, 125:3225-3234.
    • (1998) Development , vol.125 , pp. 3225-3234
    • Moallem, S.A.1    Hales, B.F.2
  • 26
    • 43449087613 scopus 로고    scopus 로고
    • Teratogen-induced distortions in the classical NF-kappaB activation pathway: correlation with the ability of embryos to survive teratogenic stress
    • Molotski N., Savion S., Gerchikov N., Fein A., Toder V., Torchinsky A. Teratogen-induced distortions in the classical NF-kappaB activation pathway: correlation with the ability of embryos to survive teratogenic stress. Toxicol. Appl. Pharmacol. 2008, 229:197-205.
    • (2008) Toxicol. Appl. Pharmacol. , vol.229 , pp. 197-205
    • Molotski, N.1    Savion, S.2    Gerchikov, N.3    Fein, A.4    Toder, V.5    Torchinsky, A.6
  • 27
    • 33845350208 scopus 로고    scopus 로고
    • Trp53 affects the developmental anomaly of clefts of the palate in irradiated mouse embryos but not clefts of the lip with or without the palate
    • Narai S., Kodama Y., Maeda Y., Yokoyama M., Takagi R., Kominami R. Trp53 affects the developmental anomaly of clefts of the palate in irradiated mouse embryos but not clefts of the lip with or without the palate. Radiat. Res. 2006, 166:877-882.
    • (2006) Radiat. Res. , vol.166 , pp. 877-882
    • Narai, S.1    Kodama, Y.2    Maeda, Y.3    Yokoyama, M.4    Takagi, R.5    Kominami, R.6
  • 28
    • 0029006469 scopus 로고
    • A teratologic suppressor role for p53 in benzo[a]pyrene-treated transgenic p53-deficient mice
    • Nicol C.J., Harrison M.L., Laposa R.R., Gimelshtein I.L., Wells P.G. A teratologic suppressor role for p53 in benzo[a]pyrene-treated transgenic p53-deficient mice. Nat. Genet. 1995, 10:181-187.
    • (1995) Nat. Genet. , vol.10 , pp. 181-187
    • Nicol, C.J.1    Harrison, M.L.2    Laposa, R.R.3    Gimelshtein, I.L.4    Wells, P.G.5
  • 29
    • 0029874308 scopus 로고    scopus 로고
    • P53-dependent apoptosis suppresses radiation-induced teratogenesis
    • Norimura T., Nomoto S., Katsuki M., Gondo Y., Kondo S. p53-dependent apoptosis suppresses radiation-induced teratogenesis. Nat. Med. 1996, 2:577-580.
    • (1996) Nat. Med. , vol.2 , pp. 577-580
    • Norimura, T.1    Nomoto, S.2    Katsuki, M.3    Gondo, Y.4    Kondo, S.5
  • 30
    • 34548008152 scopus 로고    scopus 로고
    • P53 regulates cyclophosphamide teratogenesis by controlling caspases 3, 8, 9 activation and NF-kappaB DNA binding
    • Pekar O., Molotski N., Savion S., Fein A., Toder V., Torchinsky A. p53 regulates cyclophosphamide teratogenesis by controlling caspases 3, 8, 9 activation and NF-kappaB DNA binding. Reproduction 2007, 134:379-388.
    • (2007) Reproduction , vol.134 , pp. 379-388
    • Pekar, O.1    Molotski, N.2    Savion, S.3    Fein, A.4    Toder, V.5    Torchinsky, A.6
  • 34
    • 32644434455 scopus 로고    scopus 로고
    • Teratogen-induced apoptotic cell death: does the apoptotic machinery act as a protector of embryos exposed to teratogens?
    • Torchinsky A., Fein A., Toder V. Teratogen-induced apoptotic cell death: does the apoptotic machinery act as a protector of embryos exposed to teratogens?. Birth Defects Res. C: Embryo Today 2005, 75:353-361.
    • (2005) Birth Defects Res. C: Embryo Today , vol.75 , pp. 353-361
    • Torchinsky, A.1    Fein, A.2    Toder, V.3
  • 36
    • 1242263334 scopus 로고    scopus 로고
    • To die or not to die: the function of the transcription factor NF-kappaB in embryos exposed to stress
    • Torchinsky A., Toder V. To die or not to die: the function of the transcription factor NF-kappaB in embryos exposed to stress. Am. J. Reprod. Immunol. 2004, 51:138-143.
    • (2004) Am. J. Reprod. Immunol. , vol.51 , pp. 138-143
    • Torchinsky, A.1    Toder, V.2
  • 37
    • 0347116264 scopus 로고    scopus 로고
    • Involvement of p53-dependent apoptosis in radiation teratogenesis and in the radioadaptive response in the late organogenesis of mice
    • Wang B. Involvement of p53-dependent apoptosis in radiation teratogenesis and in the radioadaptive response in the late organogenesis of mice. J. Radiat. Res. (Tokyo) 2001, 42:1-10.
    • (2001) J. Radiat. Res. (Tokyo) , vol.42 , pp. 1-10
    • Wang, B.1


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