Next-generation facilities for monoclonal antibody production

Pharmaceutical Technology

Volumn 33, Issue 7, 2009, Pages 68-73

  Guldager, Niels ^a  

^a NNE Pharmaplan   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BIOPHARMACEUTICAL INDUSTRY; CELL LINES; MONOCLONAL ANTIBODY PRODUCTION;

CELL CULTURE; PROCESS ENGINEERING; SURFACE PLASMON RESONANCE;

MONOCLONAL ANTIBODIES;

MONOCLONAL ANTIBODY;

ANTIBODY PRODUCTION; APPARATUS, EQUIPMENT AND SUPPLIES; BIOREACTOR; BIOTECHNOLOGY; CELL CULTURE; DRUG INDUSTRY; NONHUMAN; PRODUCT DEVELOPMENT; REVIEW;

EID: 77952080884     PISSN: 15432521     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (10)

1. Pharmaceutical Research and Manufacturers of America, "Biotechnology Research Continues to Bolster Arsenal Against Disease with 633 Medicines in Development," phrma.org/medicines-in-development-for-biotechnology/, accessed June 1,2009.
2. T. S. Charlebois, "Next Generation Commercial Processes," presented at IBC's 22nd International Antibody Development & Production Conference, Carlsbad, CA, 2009.
3. P. Taylor, "New PhRMA Chief Says Healthcare System is 'Broken," in-pharmatechnologist.com/On-your-radar/Globalisation/New-PhRMA-chief-says- healthcare-system-is-broken, accessed May 22,2009.
4. C. Schott, "Proactive Debottlenecking: Planning Ahead for the Downstream Bottleneck," BioProcess Int. 6 (9), 18-23 (2008).
5. T. Ryll, "How Do We Get to 30g/L using Fed-Batch Technology? What are the Limitations?" presented at IBC's 22nd International Antibody Development & Production Conference, Carlsbad, CA, 2009.
6. G.M. Ziljstra, "Monoclonal Antibody Titers of 25 g/L and Beyond with a Human Cell Line in the XDT Process," presented at ACHEMA 2009, Frankfurt, Germany (2009).
7. U. Gottschalk, "Bioseparation in Antibody Manufacturing: The Good, The Bad, and The Ugly," Biotechnol. Prog. 24 (3), 496-1453, (2008).
8. G. Jagschies, "Where is Biopharmaceutical Manufacturing Heading?" Biopharm Int. 23 (10), 16-22 (2009).
9. B. Rawlings and H. Pora, "Environmental Impact of Single Use and Reusable Bioprocess systems," BioProcess Int. 7 (2), 18-26 (2009).
10. M. Mauter, "Environmental Life-Cycle Assessment of Disposable Bioreactors," BioProcess Int. 8 (4), 18-28 (2009).