Determination of flavonoids in licorice using acid hydrolysis and reversed-phase HPLC and evaluation of the chemical quality of cultivated licorice

Planta Medica

Volumn 76, Issue 7, 2010, Pages 729-733

  Shibano, Makio ^a   Ozaki, Kazuo ^b   Watanabe, Hitoshi ^b   Tabata, Akinori ^a   Taniguchi, Masahiko ^a   Baba, Kimiye ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

^b TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

Chemical quality evaluation; Formononetin; Glycyrrhiza uralensis; Glycyrrhizin; Isoliquiritigenin; Leguminosae; Liquiritigenin

Indexed keywords

FORMONONETIN; GLYCYRRHIZA GLABRA EXTRACT; GLYCYRRHIZA URALENSIS EXTRACT; GLYCYRRHIZIC ACID; ISOLIQUIRITIGENIN; LIQUIRITIGENIN; CHALCONE DERIVATIVE; FLAVANONE DERIVATIVE; ISOFLAVONE DERIVATIVE;

ACCURACY; ARTICLE; CALIBRATION; COMMERCIAL SPECIES; CONTROLLED STUDY; CULTIVATED SPECIES; DRUG DETERMINATION; HYDROLYSIS; JAPAN; NONHUMAN; QUALITATIVE ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEEDLING; AGRICULTURE; CHEMISTRY; GLYCYRRHIZA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

FABACEAE; GLYCYRRHIZA; GLYCYRRHIZA GLABRA; GLYCYRRHIZA URALENSIS;

AGRICULTURE; CHALCONES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLAVANONES; GLYCYRRHIZA; ISOFLAVONES;

EID: 77952074410     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0029-1240690     Document Type: Article

References (11)

1. Yamamoto Y, Tani T. Growth and glycyrrhizin contents in Glycyrrhiza uralensis roots cultivated for four years in eastern Nei-Meng-gu of China. J Tradit Med 2002 19 87-92
2. Chin Y W., Jung H A., Liu Y, Su B N., Castoro J A., Keller W J., Pereira M A., Kinghorn A D. Anti-oxidant constituents of the roots and stolons of licorice (Glycyrrhiza glabra). J Agric Food Chem 2007 55 4691-4697
3. Kwon G T., Cho H J., Chung W Y., Park K K., Moon A, Park J H. Y. Isoliquiritigenin inhibits migration and invasion of prostate cancer cells: possible mediation by decreased JNK/AP-1 signaling. J Nutr Biochem 2009 20 663-676
4. Jayaprakasam B, Doddaga S, Wang R, Holmes D, Goldfarb J, Li X M. Licorice flavonoids inhibit eotaxin-1 secretion by human fetal lung fibroblasts in vitro. J Agric Food Chem 2009 57 820-825
5. Ma J, Fu N Y., Pang D B., Wu W Y., Xu A L. Apoptosis induced by isoliquiritigenin in human gastric cancer MGC-803 cells. Planta Med 2001 67 754-757
6. Kumar S, Sharma A, Madan B, Singhal V, Ghosh B. Isoliquiritigenin inhibits IB kinase activity and ROS generation to block TNF- induced expression of cell adhesion molecules on human endothelial cells. Biochem Pharmacol 2007 73 1602-1612 (Pubitemid 46533973)
7. Wang Y C., Yang Y S. Simultaneous quantification of flavonoids and triterpenoids in licorice using HPLC. J Chromatogr B Anal Technol Biomed Life Sci 2007 850 392-399
8. Li H, Chen B T., Liu L, Liu Q. Simultaneous determination of six compounds in licorice and related Chinese herbal preparations. Chromatographia 2009 69 229-235
9. Hayashi H, Inoue K, Ozaki K, Watanabe H. Comparative analysis of ten strains of Glycyrrhiza uralensis cultivated in Japan. Biol Pharm Bull 2005 28 1113-1116
10. Shibano M, Matsumoto Y, Kusano G, Shibata T. Researches of Glycyrrhiza species grown at medicinal plant gardens in Japan and basic studies for selection of pharmaceutically fine races. 1. Comparative studies by HPLC patterns and constituents of aerial parts. Nat Med 1996 50 273-283
11. Yamamoto Y, Tani T. Evaluation of glycyrrhizin variation in Gancao collected from 1986 to 2000 at drug market in Japan and discrimination of Daitou-Gancao and Dongbei-Gancao. J Tradit Med 2001 18 197-202