Management of drooling in disabled patients with scopolamine patches

British Journal of Clinical Pharmacology

Volumn 69, Issue 6, 2010, Pages 684-688

  Mato, Abigail ^a   Limeres, Jacobo ^a   Tomás, Inmaculada ^a   Muñoz, Maria ^b   Abuín, Concepción ^c   Feijoo, Javier F ^a   Diz, Pedro ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b ASPRONAGA Center for Disability and Special Care   (Spain)

^c Santiago Apóstol Center for Disabilty and Special Care   (Spain)

Author keywords

Anticholinergic; Disability; Drooling; Scopolamine; Transdermal

Indexed keywords

ANTICONVULSIVE AGENT; ANTIPARKINSON AGENT; ANXIOLYTIC AGENT; NEUROLEPTIC AGENT; PLACEBO; SCOPOLAMINE;

ADOLESCENT; ADULT; AGITATION; APPLICATION SITE REACTION; ARTICLE; AUTISM; BLOOD EXAMINATION; CEREBRAL PALSY; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DISABLED PERSON; DISEASE CLASSIFICATION; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DOWN SYNDROME; DRUG EFFICACY; DRUG WITHDRAWAL; EPILEPSY; FEMALE; HUMAN; HYPERSALIVATION; IRRITABILITY; MALE; MYDRIASIS; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUANTITATIVE ANALYSIS; RANDOMIZED CONTROLLED TRIAL; RARE DISEASE; RATING SCALE; SCHOOL CHILD; SIDE EFFECT; TREATMENT CONTRAINDICATION; URINE RETENTION;

ADMINISTRATION, CUTANEOUS; ADOLESCENT; ADULT; CHILD; CHOLINERGIC ANTAGONISTS; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; SCOPOLAMINE; SIALORRHEA; YOUNG ADULT;

EID: 77952067357     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2010.03659.x     Document Type: Article

References (23)

1. Sochaiwskyj AE, Koheil RM, Bablich K, Milner M, Kenny DJ. Oral motor functioning, frequency of swallowing and drooling in normal children and in children with cerebral palsy. Arch Phys Med Rehabil 1986 12 : 866 874. (Pubitemid 17205295)
2. Hussein I, Kerrshaw AE, Tahmasebi JF, Fayle SA. The management of drooling in children and patients with mental and physical disabilities: a literature review. Int J Paediatr Dent 1998 8 : 3 11. (Pubitemid 128506656)
3. Harris SR, Purday AH. Drooling and its management in cerebral palsy. Dev Med Child Neurol 1987 29 : 805 814.
4. Myer CMC. Sialorrhea. Pediatr Clin North Am 1989 36 : 1495 1500.
5. Limbrock GJ, Hoyer H, Scheyling H. Regulation therapy by Castillo-Morales in children with Down's syndrome: Primary and secondary orofacial pathology. ASDC J Dent Child 1990 57 : 437 441.
6. Crysdale WS, White A. Submandibular duct relocation for drooling: A 10-year experience with 194 patients. Arch Otolaryngol Head Neck Surg 1989 101 : 87 92. (Pubitemid 19194236)
7. Limbrock GJ, Hoyer H, Scheying H. Drooling, chewing and swallowing dysfunctions in children with cerebral palsy: treatment according to Castillo-Morales. ASDC J Dent Child 1990 57 : 445 451.
8. Volonte MA, Porta M, Comi G. Clinical assessment of dysphagia in early phases of Parkinson's disease. Neurol Sci 2002 23 : S121 2. (Pubitemid 35355806)
9. Meningaud JP, Pitak-Arnnop P, Chikhani L, Bertrand JC. Drooling of saliva: a review of the etiology and management options. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006 101 : 48 57. (Pubitemid 41797038)
10. Boyce HW, Bakheet MR. Sialorrhea: A review of a vexing, often unrecognized sign of oropharyngeal and esophageal disease. J Clin Gastroenterol 2005 39 : 89 97.
11. Donald PJ. Surgical rehabilitation following anterior resection for oral cavity carcinoma. Laryngoscope 1981 91 : 1941 1956.
12. Nunn JH. Drooling: review of the literature and proposals for management. J Oral Rehabil 2000 27 : 735 743.
13. Scully C, Limeres J, Gleeson M, Tomás I, Diz P. Drooling. J Oral Pathol Med 2009 38 : 321 327.
14. Talmi YP, Zohar Y. Reduction of salivary flow with transdermal scopolamine: A four-year experience. Arch Otolaryngol Head Neck Surg 1990 103 : 615 618. (Pubitemid 20360105)
15. Lewis DW, Fontana C, Mehallick LK, Everett Y. Transdermal scopolamine for reduction of drooling in developmentally delayed children. Dev Med Child Neurol 1994 36 : 484 486. (Pubitemid 24149692)
16. Thomas-Stonell N, Greenberg J. Three treatment approaches and clinical factors in the reduction of drooling. Dysphagia 1988 3 : 73 8. (Pubitemid 19067844)
17. Jongerius PH, Van Tiel P, Van Limbeek J, Gabreëls FJ, Rotteveel JJ. A systematic review for evidence of drugs to treat drooling. Arch Dis Child 2003 88 : 911 914.
18. Plante M, Morales E. Use of transdermal scopolamine to control oral secretions. Hosp Pharm 1993 28 : 608 610.
19. Dreyfuss P, Vogel D, Walsh N. The use of transdermal scopolamine to control drooling. A case report. Am J Phys Med Rehabil 1991 70 : 220 222.
20. Talmi YP, Finkelstein Y, Zohar Y, Laurian N. Reduction of salivary flow with Scopoderm TTS. Ann Otol Rhinol Laryngol 1988 97 : 128 130.
21. Brodtkorb E, Wyzocka-Bakowska MM, Lillevold PE, Sandvik L, Saunte C, Hestnes A. Transdermal scopolamine in drooling. J Ment Defic Res 1988 32 : 233 237.
22. Mato Montero A, Limeres Posse J, Tomás Carmona J, Fernandez Feijoo J, Diz Dios P. Control of drooling using transdermal scopolamine skin patches. A case report. Med Oral Patol Oral Cir Bucal 2008 13 : 27 30. (Pubitemid 351154785)
23. Saeed M, Henderson G, Dutton GN. Hyoscine skin patches for drooling dilate pupils and impair accommodation: spectacle correction for photophobia and blurred vision may be warranted. Dev Med Child Neurol 2007 49 : 426 428. (Pubitemid 46845375)