What are the limits to cell plasticity ?

Cell Research

Volumn 20, Issue 5, 2010, Pages 502-503

  Taylor, Jane ^a   Wilmut, Ian ^a   Sullivan, Gareth ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ARTICLE; CYTOLOGY; FIBROBLAST; MOUSE; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT;

ANIMALS; FIBROBLASTS; MICE; NEUROGENESIS; NEURONS;

EID: 77952051890     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2010.59     Document Type: Article

References (10)

1. Wilmut I, Schnieke AE, McWhir J, Kind AJ, Campbell KH. Viable offspring derived from fetal and adult mammalian cells. Nature 1997;385:810-813. (Pubitemid 27106068)
2. Tada M, Takahama Y, Abe K, Nakatsuji N, Tada T. Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells. Curr Biol Curr Biol 2001;1553-1558. (Pubitemid 32931020)
3. Håkelien AM, Landsverk HB, Robl JM, Skålhegg BS, Collas P. Reprogramming fbroblasts to express T-cell functions using cell extracts. Nat Biotechnol 2002;20:460-466. (Pubitemid 34495931)
4. Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fbroblast cultures by defned factors. Cell 2006;126:663-676 (Pubitemid 44233629)
5. Vierbuchen T, Ostermeier A, Pang ZP, Kokubu Y, Südhof TC, Wernig M. Direct conversion of fbroblasts to functional neurons by defned factors. Nature 2010;463:1035-1041.
6. Davis R, Weintraub H, Lassar AB. Expression of a single transfected cDNA converts fbroblasts to myoblasts. Cell 1987;51:987-1000.
7. Schäfer BW, Blakely BT, Darlington GJ, Blau HM. Effect of cell history on response to helix-loop-helix family of myogenic regulators. Nature 1990;344:454-458. (Pubitemid 20110100)
8. Boukamp P, Chen J, Gonzales F, Jones PA, Fusenig NE. Progressive stages of "transdifferentiation" from epidermal to mesenchymal phenotype induced by MyoD1 transfection, 5-aza-2'-deoxycytidine treatment, and selection for reduced cell attachment in the human keratinocyte line HaCaT. J Cell Biol 1992;116:1257-1271.
9. Wakayama T, Perry AC, Zuccotti M, Johnson KR, Yanagimachi R. Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei. Nature 1998;394:369-374. (Pubitemid 28373832)
10. Zhou Q, Brown J, Kanarek A, Rajagopal J, Melton DA. In vivo reprogramming of adult pancreatic exocrine cells to betacells. Nature 2008;455:627-632.