메뉴 건너뛰기




Volumn 23, Issue 5, 2010, Pages 644-653

EGFR and HER-2/neu expression in invasive apocrine carcinoma of the breast

Author keywords

Apocrine carcinoma; Breast; Gene amplification; HER 1 EGFR; HER 2 neu; Polysomy

Indexed keywords

ANDROGEN RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR;

EID: 77952009500     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2010.50     Document Type: Article
Times cited : (97)

References (49)
  • 1
    • 37249047990 scopus 로고    scopus 로고
    • An update on apocrine lesions of the breast
    • O'Malley FP, Bane A. An update on apocrine lesions of the breast. Histopathology 2008;52:3-10.
    • (2008) Histopathology , vol.52 , pp. 3-10
    • O'Malley, F.P.1    Bane, A.2
  • 2
    • 33646556150 scopus 로고    scopus 로고
    • Molecular pathology of breast apocrine carcinomas: A protein expression signature specific for benign apocrine metaplasia
    • Celis JE, Gromova I, Gromov P, et al. Molecular pathology of breast apocrine carcinomas: a protein expression signature specific for benign apocrine metaplasia. FEBS Lett 2006;580:2935-2944.
    • (2006) FEBS Lett. , vol.580 , pp. 2935-2944
    • Celis, J.E.1    Gromova, I.2    Gromov, P.3
  • 4
    • 0031409463 scopus 로고    scopus 로고
    • Immunohistochemical analysis of apocrine breast lesions. Consistent over-expression of androgen receptor accompanied by the loss of estrogen and progesterone receptors in apocrine metaplasia and apocrine carcinoma in situ
    • Gatalica Z. Immunohistochemical analysis of apocrine breast lesions. Consistent over-expression of androgen receptor accompanied by the loss of estrogen and progesterone receptors in apocrine metaplasia and apocrine carcinoma in situ. Pathol Res Pract 1997;193:753-758.
    • (1997) Pathol. Res. Pract. , vol.193 , pp. 753-758
    • Gatalica, Z.1
  • 5
    • 0000975209 scopus 로고    scopus 로고
    • Androgen receptor expression along with loss of bcl-2, ER, and PR expression in benign and malignant apocrine lesions of the breast: Implications for therapy
    • Tavassoli FA, Purcell CA, Bratthauer GL, et al. Androgen receptor expression along with loss of bcl-2, ER, and PR expression in benign and malignant apocrine lesions of the breast: implications for therapy. Breast J 1996;2:261-269.
    • (1996) Breast J. , vol.2 , pp. 261-269
    • Tavassoli, F.A.1    Purcell, C.A.2    Bratthauer, G.L.3
  • 6
    • 0034981511 scopus 로고    scopus 로고
    • Apocrine ductal carcinoma in situ of the breast: Histologic classification and expression of biologic markers
    • Leal C, Henrique R, Monteiro P, et al. Apocrine ductal carcinoma in situ of the breast: histologic classification and expression of biologic markers. Hum Pathol 2001;32:487-493.
    • (2001) Hum. Pathol. , vol.32 , pp. 487-493
    • Leal, C.1    Henrique, R.2    Monteiro, P.3
  • 7
    • 60449099386 scopus 로고    scopus 로고
    • The challenge of apocrine proliferations of the breast: A morphologic approach
    • Masood S, Rosa M. The challenge of apocrine proliferations of the breast: a morphologic approach. Pathol Res Pract 2009;205:155-164.
    • (2009) Pathol. Res. Pract. , vol.205 , pp. 155-164
    • Masood, S.1    Rosa, M.2
  • 8
    • 67349131843 scopus 로고    scopus 로고
    • Molecular characterization of apocrine carcinoma of the breast: Validation of an apocrine protein signature in a welldefined cohort
    • Celis JE, Cabezon T, Moreira JM, et al. Molecular characterization of apocrine carcinoma of the breast: Validation of an apocrine protein signature in a welldefined cohort. Mol Oncol 2009;3:220-237.
    • (2009) Mol. Oncol. , vol.3 , pp. 220-237
    • Celis, J.E.1    Cabezon, T.2    Moreira, J.M.3
  • 10
    • 0027264010 scopus 로고
    • Immunohistochemical demonstration of androgen receptor in breast cancer and its relationship to other prognostic factors
    • Isola JJ. Immunohistochemical demonstration of androgen receptor in breast cancer and its relationship to other prognostic factors. J Pathol 1993;170:31-35.
    • (1993) J. Pathol. , vol.170 , pp. 31-35
    • Isola, J.J.1
  • 11
    • 0036114914 scopus 로고    scopus 로고
    • Androgen and estrogen receptor mRNA status in apocrine carcinomas
    • Bratthauer GL, Lininger RA, Man YH, et al. Androgen and estrogen receptor mRNA status in apocrine carcinomas. Diagn Mol Pathol 2002;11:113-118.
    • (2002) Diagn. Mol. Pathol. , vol.11 , pp. 113-118
    • Bratthauer, G.L.1    Lininger, R.A.2    Man, Y.H.3
  • 12
    • 0042071592 scopus 로고    scopus 로고
    • Androgen receptors frequently are expressed in breast carcinomas
    • Moinfar F, Okcu M, Tsybrovskyy O, et al. Androgen receptors frequently are expressed in breast carcinomas. Cancer 2003;98:703-711.
    • (2003) Cancer , vol.98 , pp. 703-711
    • Moinfar, F.1    Okcu, M.2    Tsybrovskyy, O.3
  • 13
    • 22744448864 scopus 로고    scopus 로고
    • Identification of molecular apocrine breast tumours by microarray analysis
    • Farmer P, Bonnefoi H, Becette V, et al. Identification of molecular apocrine breast tumours by microarray analysis. Oncogene 2005;24:4660-4671.
    • (2005) Oncogene , vol.24 , pp. 4660-4671
    • Farmer, P.1    Bonnefoi, H.2    Becette, V.3
  • 14
    • 33745603978 scopus 로고    scopus 로고
    • An estrogen receptornegative breast cancer subset characterized by a hormonally regulated transcriptional program and response to androgen
    • Doane AS, Danso M, Lal P, et al. An estrogen receptornegative breast cancer subset characterized by a hormonally regulated transcriptional program and response to androgen. Oncogene 2006;25:3994-4008.
    • (2006) Oncogene , vol.25 , pp. 3994-4008
    • Doane, A.S.1    Danso, M.2    Lal, P.3
  • 15
    • 36549004041 scopus 로고    scopus 로고
    • Gene expression profiling and histopathological characterization of triple-negative/basal-like breast carcinomas
    • Kreike B, van Kouwenhove M, Horlings H, et al. Gene expression profiling and histopathological characterization of triple-negative/basal-like breast carcinomas. Breast Cancer Res 2007;9:404.
    • (2007) Breast Cancer Res. , vol.9 , pp. 404
    • Kreike, B.1    Van Kouwenhove, M.2    Horlings, H.3
  • 16
    • 70349845925 scopus 로고    scopus 로고
    • Gene expression meta-analysis supports existence of molecular apocrine breast cancer with a role for androgen receptor and implies interactions with ErbB family
    • Sanga S, Broom BM, Cristini V, et al. Gene expression meta-analysis supports existence of molecular apocrine breast cancer with a role for androgen receptor and implies interactions with ErbB family. BM Med Genomics 2009;2:59.
    • (2009) BM Med. Genomics , vol.2 , pp. 59
    • Sanga, S.1    Broom, B.M.2    Cristini, V.3
  • 17
    • 44449106252 scopus 로고    scopus 로고
    • A functionally significant cross-talk between androgen receptor and erbB2 pathways in estrogen receptor negative breast cancer
    • Naderi A, Hughes-Davies L. A functionally significant cross-talk between androgen receptor and erbB2 pathways in estrogen receptor negative breast cancer. Neoplasia 2008;10:542-548.
    • (2008) Neoplasia , vol.10 , pp. 542-548
    • Naderi, A.1    Hughes-Davies, L.2
  • 18
    • 53149133527 scopus 로고    scopus 로고
    • Refinement of breast cancer classification by molecular characterization of histological special types
    • Weigelt B, Horlings HM, Kreike B, et al. Refinement of breast cancer classification by molecular characterization of histological special types. J Pathol 2008;216:141-150.
    • (2008) J. Pathol. , vol.216 , pp. 141-150
    • Weigelt, B.1    Horlings, H.M.2    Kreike, B.3
  • 19
    • 42749096861 scopus 로고    scopus 로고
    • Apocrine carcinomas of the breast in Turkish women: Hormone receptors, c-erbB-2 and p53 immunoexpression
    • Kaya H, Bozkurt SU, Erbarut I, et al. Apocrine carcinomas of the breast in Turkish women: hormone receptors, c-erbB-2 and p53 immunoexpression. Pathol Res Pract 2008;204:367-371.
    • (2008) Pathol. Res. Pract. , vol.204 , pp. 367-371
    • Kaya, H.1    Bozkurt, S.U.2    Erbarut, I.3
  • 20
    • 0036046707 scopus 로고    scopus 로고
    • Histological and immunohistochemical analysis of apocrine breast carcinoma
    • Matsuo K, Fukutomi T, Hasegawa T, et al. Histological and immunohistochemical analysis of apocrine breast carcinoma. Breast Cancer 2002;9:43-49.
    • (2002) Breast Cancer , vol.9 , pp. 43-49
    • Matsuo, K.1    Fukutomi, T.2    Hasegawa, T.3
  • 22
    • 54449091620 scopus 로고    scopus 로고
    • Polysomy 17 in breast cancer: Clinicopathologic significance and impact on HER-2 testing
    • Vanden Bempt I, Van Loo P, Drijkoningen M, et al. Polysomy 17 in breast cancer: clinicopathologic significance and impact on HER-2 testing. J Clin Oncol 2008;26:4869-4874.
    • (2008) J. Clin. Oncol. , vol.26 , pp. 4869-4874
    • Bempt, I.V.1    Van Loo, P.2    Drijkoningen, M.3
  • 23
    • 12244257781 scopus 로고    scopus 로고
    • Breast carcinoma in women over the age of 85: Distinct histological pattern an androgen, oestrogen, and progesterone receptor status
    • Honma N, Sakamoto G, Akiyama F, et al. Breast carcinoma in women over the age of 85: distinct histological pattern an androgen, oestrogen, and progesterone receptor status. Histopathology 2003;42:120-127.
    • (2003) Histopathology , vol.42 , pp. 120-127
    • Honma, N.1    Sakamoto, G.2    Akiyama, F.3
  • 24
    • 33847147313 scopus 로고    scopus 로고
    • American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer
    • Wolff AC, Hammond ME, Schwartz JN, et al. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. J Clin Oncol 2007;25:118-145.
    • (2007) J. Clin. Oncol. , vol.25 , pp. 118-145
    • Wolff, A.C.1    Hammond, M.E.2    Schwartz, J.N.3
  • 25
    • 68249110633 scopus 로고    scopus 로고
    • Poor prognostic significance of unamplified chromosome 17 polysomy in invasive breast carcinoma
    • Krishnamurti U, Hammers JL, Atem FD, et al. Poor prognostic significance of unamplified chromosome 17 polysomy in invasive breast carcinoma. Mod Pathol 2009;22:1044-1048.
    • (2009) Mod. Pathol. , vol.22 , pp. 1044-1048
    • Krishnamurti, U.1    Hammers, J.L.2    Atem, F.D.3
  • 26
    • 0346500480 scopus 로고    scopus 로고
    • Determination of HER-2 status and chromosome 17 polysomy in breast carcinomas comparing HercepTest and Path-Vysion FISH assay
    • Varshney D, Zhou YY, Geller SA, et al. Determination of HER-2 status and chromosome 17 polysomy in breast carcinomas comparing HercepTest and Path-Vysion FISH assay. Am J Clin Pathol 2004;121:70-77.
    • (2004) Am. J. Clin. Pathol. , vol.121 , pp. 70-77
    • Varshney, D.1    Zhou, Y.Y.2    Geller, S.A.3
  • 27
    • 41749121507 scopus 로고    scopus 로고
    • Optimization of the Affymetrix GeneChip mapping 10 K 2.0 assay for routine clinical use on formalin fixed paraffin embedded tissues
    • Lyons-Weiler M, Hagenkord J, Sciulli CM, et al. Optimization of the Affymetrix GeneChip mapping 10 K 2.0 assay for routine clinical use on formalin fixed paraffin embedded tissues. Diagn Mol Pathol 2008;17:3-13.
    • (2008) Diagn Mol. Pathol. , vol.17 , pp. 3-13
    • Lyons-Weiler, M.1    Hagenkord, J.2    Sciulli, C.M.3
  • 28
    • 42549085633 scopus 로고    scopus 로고
    • Whole genome SNP arrays as a potential diagnostic tool for the detection of characteristic chromosomal aberrations in renal epithelial tumors
    • Monzon FA, Hagenkord J, Lyons-Weiler M, et al. Whole genome SNP arrays as a potential diagnostic tool for the detection of characteristic chromosomal aberrations in renal epithelial tumors. Mod Pathol 2008;21:599-608.
    • (2008) Mod. Pathol. , vol.21 , pp. 599-608
    • Monzon, F.A.1    Hagenkord, J.2    Lyons-Weiler, M.3
  • 29
    • 4143150688 scopus 로고    scopus 로고
    • Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma
    • Nielsen TO, Hsu FD, Jensen K, et al. Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma. Clin Cancer Res 2004;10:5367-5374.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 5367-5374
    • Nielsen, T.O.1    Hsu, F.D.2    Jensen, K.3
  • 30
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • Sørlie T, Perou CM, Tibshirani R, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 2001;98:10869-10874.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 10869-10874
    • Sørlie, T.1    Perou, C.M.2    Tibshirani, R.3
  • 31
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumours
    • Perou CM, SØrlie T, Eisen MB, et al. Molecular portraits of human breast tumours. Nature 2000;406:747-752.
    • (2000) Nature , vol.406 , pp. 747-752
    • Perou, C.M.1    SØrlie, T.2    Eisen, M.B.3
  • 32
    • 34248148215 scopus 로고    scopus 로고
    • Androgens and androgen receptors: A clinically neglected sector in breast cancer biology
    • Moe RE, Anderson BO. Androgens and androgen receptors: a clinically neglected sector in breast cancer biology. J Surg Oncol 2007;95:437-439.
    • (2007) J. Surg. Oncol. , vol.95 , pp. 437-439
    • Moe, R.E.1    Anderson, B.O.2
  • 33
    • 0242300581 scopus 로고    scopus 로고
    • Androgen receptor expression in estrogen receptor-negative breast cancer. Immunohistochemical, clinical, and prognostic associations
    • Agoff SN, Swanson PE, Linden H, et al. Androgen receptor expression in estrogen receptor-negative breast cancer. Immunohistochemical, clinical, and prognostic associations. Am J Clin Pathol 2003;120:725-731.
    • (2003) Am. J. Clin. Pathol. , vol.120 , pp. 725-731
    • Agoff, S.N.1    Swanson, P.E.2    Linden, H.3
  • 34
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon D, Clark G, Wong S, et al. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987;235:177-182.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.1    Clark, G.2    Wong, S.3
  • 35
    • 62449090881 scopus 로고    scopus 로고
    • Guidelines for human epidermal growth factor receptor 2 testing: Biologic and methodologic considerations
    • Sauter G, Lee J, Bartlett JM, et al. Guidelines for human epidermal growth factor receptor 2 testing: biologic and methodologic considerations. J Clin Oncol 2009;27:1323-1333.
    • (2009) J. Clin. Oncol. , vol.27 , pp. 1323-1333
    • Sauter, G.1    Lee, J.2    Bartlett, J.M.3
  • 36
    • 1842855321 scopus 로고    scopus 로고
    • Preferential HER-2/neu overexpression and/or amplification in aggressive histological subtypes of invasive breast cancer
    • Varga Z, Zhao J, Öhlschlegel C, et al. Preferential HER-2/neu overexpression and/or amplification in aggressive histological subtypes of invasive breast cancer. Histopathology 2004;44:332-338.
    • (2004) Histopathology , vol.44 , pp. 332-338
    • Varga, Z.1    Zhao, J.2    Öhlschlegel, C.3
  • 37
    • 67149146200 scopus 로고    scopus 로고
    • Prevalence, morphologic features and proliferation indices of breast carcinoma molecular classes using immunohistochemical surrogate markers
    • Bhargava R, Striebel J, Beriwal S, et al. Prevalence, morphologic features and proliferation indices of breast carcinoma molecular classes using immunohistochemical surrogate markers. Int J Clin Exp Pathol 2009;2:444-455.
    • (2009) Int. J. Clin. Exp. Pathol. , vol.2 , pp. 444-455
    • Bhargava, R.1    Striebel, J.2    Beriwal, S.3
  • 38
    • 52549093971 scopus 로고    scopus 로고
    • High concordance between immunohistochemistry and fluorescence in situ hybridization testing for HER2 status in breast cancer requires a normalized IHC scoring system
    • Gown AM, Goldstein LC, Barry TS, et al. High concordance between immunohistochemistry and fluorescence in situ hybridization testing for HER2 status in breast cancer requires a normalized IHC scoring system. Mod Pathol 2008;21:1271-1277.
    • (2008) Mod. Pathol. , vol.21 , pp. 1271-1277
    • Gown, A.M.1    Goldstein, L.C.2    Barry, T.S.3
  • 39
    • 0037272682 scopus 로고    scopus 로고
    • Chromosome 17 aneusomy is associated with poor prognostic factors in invasive breast carcinoma
    • Watters AD, Going JJ, Cooke TG, et al. Chromosome 17 aneusomy is associated with poor prognostic factors in invasive breast carcinoma. Breast Cancer Res Treat 2003;77:109-114.
    • (2003) Breast Cancer Res. Treat , vol.77 , pp. 109-114
    • Watters, A.D.1    Going, J.J.2    Cooke, T.G.3
  • 40
    • 0036183416 scopus 로고    scopus 로고
    • Aneusomy 17 in breast cancer: Its role in HER-2/neu protein expression and implication for clinical assessment of HER-2/neu status
    • Wang S, Saboorian MH, Frenkel EP, et al. Aneusomy 17 in breast cancer: Its role in HER-2/neu protein expression and implication for clinical assessment of HER-2/neu status. Mod Pathol 2002;15:137-145.
    • (2002) Mod. Pathol. , vol.15 , pp. 137-145
    • Wang, S.1    Saboorian, M.H.2    Frenkel, E.P.3
  • 41
    • 69549124028 scopus 로고    scopus 로고
    • Clinical validation of an array CGH test for HER2 status in breast cancer reveals that polysomy 17 is a rare event
    • Yeh IT, Martin MA, Robetorye RS, et al. Clinical validation of an array CGH test for HER2 status in breast cancer reveals that polysomy 17 is a rare event. Mod Pathol 2009;22:1169-1175.
    • (2009) Mod. Pathol. , vol.22 , pp. 1169-1175
    • Yeh, I.T.1    Martin, M.A.2    Robetorye, R.S.3
  • 42
    • 18344390418 scopus 로고    scopus 로고
    • ERBB receptors and cancer: The complexity of targeted inhibitors
    • Hynes NE, Lane HA. ERBB receptors and cancer: the complexity of targeted inhibitors. Nature Rev Cancer 2005;5:341-354.
    • (2005) Nature Rev. Cancer , vol.5 , pp. 341-354
    • Hynes, N.E.1    Lane, H.A.2
  • 43
    • 63149108552 scopus 로고    scopus 로고
    • Mutations and response to epidermal growth factor receptor inhibitors
    • Laurent-Puig P, Lievre A, Blons H. Mutations and response to epidermal growth factor receptor inhibitors. Clin Cancer Res 2009;15:1133-1139.
    • (2009) Clin. Cancer Res. , vol.15 , pp. 1133-1139
    • Laurent-Puig, P.1    Lievre, A.2    Blons, H.3
  • 44
    • 24044520039 scopus 로고    scopus 로고
    • EGFR gene amplification in breast cancer: Correlation with epidermal growth factor receptor mRNA and protein expression and HER-2 status and absence of EGFR-activating mutations
    • Bhargava R, Gerald WL, Li AR, et al. EGFR gene amplification in breast cancer: correlation with epidermal growth factor receptor mRNA and protein expression and HER-2 status and absence of EGFR-activating mutations. Mod Pathol 2005;18:1027-1033.
    • (2005) Mod. Pathol. , vol.18 , pp. 1027-1033
    • Bhargava, R.1    Gerald, W.L.2    Li, A.R.3
  • 45
    • 34548646565 scopus 로고    scopus 로고
    • EGFR gene and protein expression in breast cancers
    • Park K, Han S, Shin E, et al. EGFR gene and protein expression in breast cancers. Euro J Surg Oncol 2007;33:956-960.
    • (2007) Euro J. Surg. Oncol. , vol.33 , pp. 956-960
    • Park, K.1    Han, S.2    Shin, E.3
  • 46
    • 20244379711 scopus 로고    scopus 로고
    • Characterization of HER1 (c-erbB1) status in locally advanced breast cancer using fluorescence in situ hybridization and immunohistochemistry
    • Corzo C, Tusquets I, Salido M, et al. Characterization of HER1 (c-erbB1) status in locally advanced breast cancer using fluorescence in situ hybridization and immunohistochemistry. Tumour Biol 2005;26:25-30.
    • (2005) Tumour Biol. , vol.26 , pp. 25-30
    • Corzo, C.1    Tusquets, I.2    Salido, M.3
  • 47
    • 28544438282 scopus 로고    scopus 로고
    • Numerical aberrations of chromosomes 1 and 7 by fluorescent in situ hybridization and DNA ploidy analysis in breast cancer
    • Kapranos N, Kounelis S, Karantasis H, et al. Numerical aberrations of chromosomes 1 and 7 by fluorescent in situ hybridization and DNA ploidy analysis in breast cancer. Breast J 2005;11:448-453.
    • (2005) Breast J. , vol.11 , pp. 448-453
    • Kapranos, N.1    Kounelis, S.2    Karantasis, H.3
  • 48
    • 0032937805 scopus 로고    scopus 로고
    • Numerical abnormalities of chromosome 7 in interphase cell nuclei of breast carcinoma have no impact on immunohistochemically determined EGFR status
    • Sauer T, Beraki K, Jebsen PW, et al. Numerical abnormalities of chromosome 7 in interphase cell nuclei of breast carcinoma have no impact on immunohistochemically determined EGFR status. AP-MIS 1999;107:211-216.
    • (1999) AP-MIS , vol.107 , pp. 211-216
    • Sauer, T.1    Beraki, K.2    Jebsen, P.W.3
  • 49
    • 79551654748 scopus 로고    scopus 로고
    • Chromosome 7 aneusomy in metaplastic breast carcinomas with chondroid, squamous, and spindle-cell differentiation
    • doi:10.1177/1066896909334127
    • Gwin K, Lezon-Geyda K, Harris L, et al. Chromosome 7 aneusomy in metaplastic breast carcinomas with chondroid, squamous, and spindle-cell differentiation. Int J Surg Pathol 2009; doi:10.1177/1066896909334127
    • (2009) Int. J. Surg. Pathol.
    • Gwin, K.1    Lezon-Geyda, K.2    Harris, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.