Inaccuracies in 24-hour urine testing for monoclonal gammopathies: Serum free light chain analysis provides a more accurate measure of light chain burden than urine protein electrophoresis

Laboratory Medicine

Volumn 40, Issue 6, 2009, Pages 341-344

  Siegel, David S ^a   McBride, Laura ^a   Bilotti, Elizabeth ^a   Lendvai, Nikoletta ^a   Gonsky, Jason ^a   Berges, Thomas ^a   Schillen, Danielle ^a   McNeill, Ann ^a   Schmidt, Linda ^a   Van Hoeven, Karen H ^b  

^a HACKENSACK UNIVERSITY MEDICAL CENTER   (United States)

^b Binding Site Group Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

M PROTEIN; PROTEIN;

ADULT; AGED; ANALYTICAL ERROR; ARTICLE; CREATININE CLEARANCE; DIAGNOSTIC ERROR; FEMALE; HUMAN; INTERMETHOD COMPARISON; LIGHT CHAIN; MAJOR CLINICAL STUDY; MALE; MONOCLONAL IMMUNOGLOBULINEMIA; PROTEIN ANALYSIS; PROTEIN ELECTROPHORESIS; PROTEIN URINE LEVEL; SERUM; URINALYSIS;

EID: 77951991896     PISSN: 00075027     EISSN: None     Source Type: Journal    
DOI: 10.1309/LMXYGLRB6YEBWHCJ     Document Type: Article

References (4)

1. Dispenzieri A, Kyle R, Merlini G, et al. International Myeloma Working Group guidelines for serum-free light chain analysis in multiple myeloma and related disorders. Leukemia. 2009;23:215-224.
2. Kyle RA, Yee GC, Somerfield MR, et al. American Society of Clinical Oncology 2007 clinical practice guideline update on the role of bisphosphonates in multiple myeloma. J Clin Oncol. 2007;25:2464-2472.
3. Dispenzieri A, Zhang L, Katzmann JA, et al. Appraisal of immunoglobulin free light chain as a marker of response. Blood. 2008;111:4908-4915. (Pubitemid 351451470)
4. Snozek CL, Katzmann JA, Kyle RA, et al. Prognostic value of the serum free light chain ratio in newly diagnosed myeloma: Proposed incorporation into the international staging system. Leukemia. 2008;22:1933-1937.