The effect of the dosage of NT-3/chitosan carriers on the proliferation and differentiation of neural stem cells

Biomaterials

Volumn 31, Issue 18, 2010, Pages 4846-4854

  Yang, Zhaoyang ^a   Duan, Hongmei ^b   Mo, Linhong ^b   Qiao, Hui ^c   Li, Xiaoguang ^a,b  

^a BEIHANG UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c NINGXIA MEDICAL UNIVERSITY   (China)

Author keywords

Cell differentiation; Chitosan carriers; Neural stem cells; Neuron; NT 3

Indexed keywords

3-DIMENSIONAL; CELL DIFFERENTIATION; CELL TRANSPLANTATION; CELL VIABILITY; COCULTURE; DIFFERENTIATED CELLS; IN-VITRO; NEURAL CELLS; NEURAL STEM CELL; NEURAL STEM CELLS; NEUROTROPHIC FACTORS; OPTIMAL DOSAGE; RELEASING KINETICS; SPINAL INJURY;

AMPLIFICATION; CELL CULTURE; CHITIN; CHITOSAN; NEURONS;

STEM CELLS;

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CHITOSAN; NEUROTROPHIN 3;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL ASSAY; CELL CULTURE; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSPLANTATION; CELL VIABILITY; COCULTURE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NEWBORN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; CHITOSAN; DRUG CARRIERS; MULTIPOTENT STEM CELLS; NEUROGENESIS; NEURONS; NEUROTROPHIN 3; RATS; RATS, WISTAR; SPINAL CORD;

EID: 77951975775     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.02.015     Document Type: Article

References (43)

1. Bithell A., Williams B.P. Neural stem cells and cell replacement therapy: making the right cells. Clin Sci (Lond) 2005, 108:13-22.
2. Wang Y., Chen S., Yang D., Le W.D. Stem cell transplantation: a promising therapy for parkinson's disease. J Neuroimmune Pharmacol 2007, 2:243-250.
3. Dutton R., Yamada T., Turnley A., Bartlett P.F., Murphy M. Sonic hedgehog promotes neuronal differentiation of murine spinal cord precursors and collaborates with neurotrophin 3 to induce islet-1. J Neurosci 1999, 19:2601-2608.
4. Caldwell M.A., He X., Wilkie N., Pollack S., Marshall G., Wafford K.A., et al. Growth factors regulate the survival and fate of cells derived from human neurospheres. Nat Biotechnol 2001, 19:475-479.
5. Calza L., Giuliani A., Fernandez M., Pirondi S., D'Intino G., Aloe L., et al. Neural stem cells and cholinergic neurons: regulation by immunolesion and treatment with mitogens, retinoic acid, and nerve growth factor. Proc Natl Acad Sci 2003, 100:7325-7330.
6. Hapner S.J., Nielsen K.M., Chaverra M., Esper R.M., Loeb J.A., Lefcort F. NT-3 and cntf exert dose-dependent, pleiotropic effects on cells in the immature dorsal root ganglion: neuregulin-mediated proliferation of progenitor cells and neuronal differentiation. Dev Biol 2006, 297:182-197.
7. Ito H., Nakajima A., Nomoto H., Furukawa S. Neurotrophins facilitate neuronal differentiation of cultured neural stem cells via induction of MRNA expression of basic helix-loop-helix transcription factors mash1 and math1. J Neurosci Res 2003, 71:648-658.
8. Zhao L.X., Zhang J., Cao F., Meng L., Wang D.M., Li Y.H., et al. Modification of the brain-derived neurotrophic factor gene: a portal to transform mesenchymal stem cells into advantageous engineering cells for neuroregeneration and neuroprotection. Exp Neurol 2004, 190:396-406.
9. Longhi L., Watson D.J., Saatman K.E., Thompson H.J., Zhang C., Fujimoto S., et al. Ex vivo gene therapy using targeted engraftment of NGF-expressing human nt2n neurons attenuates cognitive deficits following traumatic brain injury in mice. J Neurotrauma 2004, 21:1723-1736.
10. Watson D.J., Longhi L., Lee E.B., Fulp C.T., Fujimoto S., Royo N.C., et al. Genetically modified nt2n human neuronal cells mediate long-term gene expression as cns grafts in vivo and improve functional cognitive outcome following experimental traumatic brain injury. J Neuropathol Exp Neurol 2003, 62:368-380.
11. Grill R., Murai K., Blesch A., Gage F.H., Tuszynski M.H. Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury. J Neurosci 1997, 17:5560-5572.
12. Liu Y., Himes B.T., Solowska J., Moul J., Chow S.Y., Park K.I., et al. Intraspinal delivery of neurotrophin-3 using neural stem cells genetically modified by recombinant retrovirus. Exp Neurol 1999, 158:9-26.
13. Park K.I., Himes B.T., Stieg P.E., Tessler A., Fischer I., Snyder E.Y. Neural stem cells may be uniquely suited for combined gene therapy and cell replacement: evidence from engraftment of neurotrophin-3-expressing stem cells in hypoxic-ischemic brain injury. Exp Neurol 2006, 199:179-190.
14. Cheng H., Huang Y.C., Chang P.T., Huang Y.Y. Laminin-incorporated nerve conduits made by plasma treatment for repairing spinal cord injury. Biochem Biophys Res Commun 2007, 357:938-944.
15. Li X.G., Yang Z.Y., Yang Y. Morphological and electrophysiological evidence for regeneration of transected spinal cord fibers and restoration of motor functions in adult rats. Chin Sci Bull 2006, 51:918-926.
16. Gao E.J., Liu B.F., Lu Q., Liu Y.J., Cai Q., Li X.G. Biocompatability of chitosan bioactive carriers implanted into rat cortex. Chin J Rehabil Theor Pract 2004, 10:28-30. [in Chinese].
17. Li X.G., Yang Z.Y., Zhang A.F., Wang T.L. ChenWC. Repair of thoracic spinal cord injury by chitosan tube implantation in adult rats. Biomaterials 2009, 30:1121-1132.
18. Li X.G., Yang Z.Y., Yang Y. Studies on repairing of hemisected thoracic spinal cord of adult rats by using a chitosan tube filled with alginate fibers. Prog Nat Sci 2006, 16:1051-1055.
19. Li X.G., Yang Z.Y., Zhang A.F. The effect of neurotrophin-3/chitosan carriers on the proliferation and differentiation of neural stem cells. Biomaterials 2009, 30:4978-4985.
20. Tzeng S.F. Neural progenitors isolated from newborn rat spinal cords differentiate into neurons and astroglia. J Biomed Sci 2002, 9:10-16.
21. Johe K.K., Hazel T.G., Muller T., Dugich-Djordjevic M.M., McKay R.D. Single factors direct the differentiation of stem cells from the fetal an adult central nervous system. Genes Dev 1996, 10:3129-3140.
22. Hung C.H., Lin Y.L., Young T.H. The effect of chitosan and PVDF substrates on the behavior of embryonic rat cerebral cortical stem cells. Biomaterials 2006, 27:4461-4469.
23. Wang J.H., Hung C.H., Young T.H. Proliferation and differentiation of neural stem cells on lysine-alanine sequential polymer substrates. Biomaterials 2006, 27:3441-3450.
24. Zheng L.H., Lin L. Theory and practice of neural cell culture 2002, Science Press, Beijing, pp. 195-7 [in Chinese].
25. Iikhanizadeh S., Teixeira A.I., Hermanson O. Inkjet printing of macromolecules on hydrogels to steer neural stem cell differentiation. Biomaterials 2007, 28:3936-3943.
26. Young T.H., Hung C.H. Behavior of embryonic rat cerebral cortical stem cells on the PVA and EVAL substrates. Biomaterials 2005, 26:4291-4299.
27. Cao Q.L., Zhang Y.P., Howard R.M., Walters W.M., Tsoulfas P., Whittemore S.R. Pluripotent stem cells engrafted into the normal or lesioned adult rat spinal cord are restricted to a glial lineage. Exp Neurol 2001, 167:48-58.
28. Cao Q.L., Howard R.M., Dennison J.B., Whittemore S.R. Differentiation of engrafted neuronal-restricted precursor cells is inhibited in the traumatically injured spinal cord. Exp Neurol 2002, 177:349-359.
29. Chow S.Y., Moul J., Tobias C.A., Himes B.T., Liu Y., Obrocka M., et al. Characterization and intraspinal grafting of egf/bfgf-dependent neurospheres derived from embryonic rat spinal cord. Brain Res 2000, 874:87-106.
30. Gage F.H., Coates P.W., Palmer T.D., Kuhn H.G., Fisher L.G., Suhonen J.O., et al. Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain. Proc Natl Acad Sci 1995, 92:11879-11883.
31. Lepore A.C., Han S.S., Tyler-Polsz C.J., Cai J., Rao M.S., Fischer I. Differential fate of multipotent and lineage-restricted neural precursors following transplantation into the adult cns. Neuron Glia Biol 2004, 1:113-126.
32. Lundberg C., Martinez-Serrano A., Cattaneo E., McKay R.D., Bjorklund A. Survival, integration, and differentiation of neural stem cell lines after transplantation to the adult rat striatum. Exp Neurol 1997, 145:342-360.
33. Shihabuddin L.S., Horner P.J., Ray J., Gage F.H. Adult spinal cord stem cells generate neurons after transplantation in the adult dentate gyrus. J Neurosci 2000, 20:8727-8735.
34. Shindo T., Matsumoto Y., Wang Q., Kawai N., Tamiya T., Nagao S. Differences in the neuronal stem cells survival, neuronal differentiation and neurological improvement after transplantation of neural stem cells between mild and severe experimental traumatic brain injury. J Med Invest 2006, 53:42-51.
35. Svendsen C.N., Caldwell M.A., Shen J., ter Borg M.G., Rosser A.E., Tyers P., et al. Long-term survival of human central nervous system progenitor cells transplanted into a rat model of parkinson's disease. Exp Neurol 1997, 148:135-146.
36. Winkler C., Fricker R.A., Gates M.A., Olsson M., Hammang J.P., Carpenter M.K., et al. Incorporation and glial differentiation of mouse egf-responsive neural progenitor cells after transplantation into the embryonic rat brain. Mol Cell Neurosci 1998, 11:99-116.
37. Yan J., Welsh A.M., Bora S.H., Snyder E.Y., Koliatsos V.E. Differentiation and tropic/trophic effects of exogenous neural precursors in the adult spinal cord. J Comp Neurol 2004, 480:101-114.
38. Guo J.S., Zeng Y.S., Li H.B., Huang W.L., Liu R.Y., Li X.B., et al. Cotransplant of neural stem cells and nt-3 gene modified schwann cells promote the recovery of transected spinal cord injury. Spinal Cord 2007, 45:15-24.
39. Lu H.X., Li M.J., Song T.S., Qian Y.H., Xiao X.L., Chen X.L., et al. Retrovirus delivered neurotrophin-3 promotes survival, proliferation and neuronal differentiation of human fetal neural stem cells in vitro. Brain Res Bull 2008, 77:158-164.
40. Lamballe F., Klein R., Barbacid M. TrkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3. Cell 1991, 66:967-979.
41. Zigmond SH, Consequences of chemotactic peptide receptor modulation for leukocyte orientation. J Cell Biol 88, 644-647.
42. Burdick J.A., Ward M., Liang E., Young M.J., Langer R. Stimulation of neurite outgrowth by neurotrophins delivered from degradable hydrogels. Biomaterials 2006, 27:452-459.
43. Taylor S.J., Sakiyama-Elbert S.E. Effect of controlled delivery of neurotrophin-3 from fibrin on spinal cord injury in a long term model. J Control Release 2006, 116:204-210.