메뉴 건너뛰기




Volumn 21, Issue 5, 2010, Pages 533-541

Redirecting the immune response: Role of adoptive T cell therapy

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BUSULFAN; CANCER VACCINE; CD4 ANTIGEN; CD40 LIGAND MONOCLONAL ANTIBODY; CD8 ANTIGEN; CYCLOPHOSPHAMIDE; FLUDARABINE; GEMCITABINE; INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 21; INTERLEUKIN 7; LENTIVIRUS VECTOR; MELPHALAN; RECOMBINANT INTERLEUKIN 15; RECOMBINANT INTERLEUKIN 7; RETROVIRUS VECTOR; TREOSULFAN;

EID: 77951967198     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.2010.033     Document Type: Review
Times cited : (8)

References (102)
  • 6
  • 7
    • 70349342731 scopus 로고    scopus 로고
    • Adoptive immu-notherapy for cancer: The next generation of gene-engineered immune cells
    • Berry, L.J., Moeller, M., and Darcy, P.K. (2009). Adoptive immu-notherapy for cancer: The next generation of gene-engineered immune cells. Tissue Antigens 74, 277-289.
    • (2009) Tissue Antigens , vol.74 , pp. 277-289
    • Berry, L.J.1    Moeller, M.2    Darcy, P.K.3
  • 8
    • 0032946001 scopus 로고    scopus 로고
    • Serum levels of IL-7 in bone marrow transplant recipients: Relationship to clinical characteristics and lymphocyte count
    • Bolotin, E., Annett, G., Parkman, R., and Weinberg, K. (1999). Serum levels of IL-7 in bone marrow transplant recipients: Relationship to clinical characteristics and lymphocyte count. Bone Marrow Transplant. 23, 783-788.
    • (1999) Bone Marrow Transplant. , vol.23 , pp. 783-788
    • Bolotin, E.1    Annett, G.2    Parkman, R.3    Weinberg, K.4
  • 9
    • 33846878993 scopus 로고    scopus 로고
    • Cyclophosphamide enhances the anti-tumor efficacy of adoptively transferred immune cells through the induction of cytokine expression, B-cell and T-cell ho-meostatic proliferation, and specific tumor infiltration
    • Bracci, L., Moschella, F., Sestili, P., La Sorsa, V., Valentini, M., Canini, I., Baccarini, S., Maccari, S., Ramoni, C., Belardelli, F., and Proietti, E. (2007). Cyclophosphamide enhances the anti-tumor efficacy of adoptively transferred immune cells through the induction of cytokine expression, B-cell and T-cell ho-meostatic proliferation, and specific tumor infiltration. Clin. Cancer Res. 13, 644-653.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 644-653
    • Bracci, L.1    Moschella, F.2    Sestili, P.3    La Sorsa, V.4    Valentini, M.5    Canini, I.6    Baccarini, S.7    MacCari, S.8    Ramoni, C.9    Belardelli, F.10    Proietti, E.11
  • 10
    • 24744458859 scopus 로고    scopus 로고
    • Partial, but not complete, tumor-debulking surgery promotes protective antitumor memory when combined with chemotherapy and adjuvant immunotherapy
    • Broomfield, S., Currie, A., van der Most, R.G., Brown, M., van Bruggen, I., Robinson, B.W., and Lake, R.A. (2005). Partial, but not complete, tumor-debulking surgery promotes protective antitumor memory when combined with chemotherapy and adjuvant immunotherapy. Cancer Res. 65, 7580-7584.
    • (2005) Cancer Res. , vol.65 , pp. 7580-7584
    • Broomfield, S.1    Currie, A.2    Van Der Most, R.G.3    Brown, M.4    Van Bruggen, I.5    Robinson, B.W.6    Lake, R.A.7
  • 11
    • 0030001675 scopus 로고    scopus 로고
    • Lymphocyte homing and homeostasis
    • Butcher, E.C., and Picker, L.J. (1996). Lymphocyte homing and homeostasis. Science 272, 60-66.
    • (1996) Science , vol.272 , pp. 60-66
    • Butcher, E.C.1    Picker, L.J.2
  • 13
    • 67650467728 scopus 로고    scopus 로고
    • Modulating T-cell homeostasis with IL-7: Preclinical and clinical studies
    • Capitini, C.M., Chisti, A.A., and Mackall, C.L. (2009). Modulating T-cell homeostasis with IL-7: Preclinical and clinical studies. J. Intern. Med. 266, 141-153.
    • (2009) J. Intern. Med. , vol.266 , pp. 141-153
    • Capitini, C.M.1    Chisti, A.A.2    MacKall, C.L.3
  • 14
    • 14844353314 scopus 로고    scopus 로고
    • The immunogenicity of dendritic cell-based vaccines is not hampered by doxorubicin and melphalan administration
    • Casati, A., Zimmermann, V.S., Benigni, F., Bertilaccio, M.T., Bellone, M., and Mondino, A. (2005). The immunogenicity of dendritic cell-based vaccines is not hampered by doxorubicin and melphalan administration. J. Immunol. 174, 3317-3325.
    • (2005) J. Immunol. , vol.174 , pp. 3317-3325
    • Casati, A.1    Zimmermann, V.S.2    Benigni, F.3    Bertilaccio, M.T.4    Bellone, M.5    Mondino, A.6
  • 16
    • 0037481021 scopus 로고    scopus 로고
    • Human T lymphocytes transduced by lentiviral vectors in the absence of TCR activation maintain an intact immune competence
    • Cavalieri, S., Cazzaniga, S., Geuna, M., Magnani, Z., Bordignon, C., Naldini, L., and Bonini, C. (2003). Human T lymphocytes transduced by lentiviral vectors in the absence of TCR activation maintain an intact immune competence. Blood 102, 497-505.
    • (2003) Blood , vol.102 , pp. 497-505
    • Cavalieri, S.1    Cazzaniga, S.2    Geuna, M.3    Magnani, Z.4    Bordignon, C.5    Naldini, L.6    Bonini, C.7
  • 17
    • 44649197976 scopus 로고    scopus 로고
    • The combination of cyclophosphamide and human T cells genetically engineered to target CD19 can eradicate established B-cell lymphoma
    • Cheadle, E.J., Gilham, D.E., and Hawkins, R.E. (2008). The combination of cyclophosphamide and human T cells genetically engineered to target CD19 can eradicate established B-cell lymphoma. Br. J. Haematol. 142, 65-68.
    • (2008) Br. J. Haematol. , vol.142 , pp. 65-68
    • Cheadle, E.J.1    Gilham, D.E.2    Hawkins, R.E.3
  • 25
    • 67650638846 scopus 로고    scopus 로고
    • T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model
    • Di Stasi, A., De Angelis, B., Rooney, C.M., Zhang, L., Mahen-dravada, A., Foster, A.E., Heslop, H.E., Brenner, M.K., Dotti, G., and Savoldo, B. (2009). T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model. Blood 113, 6392-6402.
    • (2009) Blood , vol.113 , pp. 6392-6402
    • Di Stasi, A.1    De Angelis, B.2    Rooney, C.M.3    Zhang, L.4    Mahen-Dravada, A.5    Foster, A.E.6    Heslop, H.E.7    Brenner, M.K.8    Dotti, G.9    Savoldo, B.10
  • 26
    • 70449123840 scopus 로고    scopus 로고
    • Fifteen years of gene therapy based on chimeric antigen receptors: "Are we nearly there yet?"
    • Dotti, G., Savoldo, B., and Brenner, M. (2009). Fifteen years of gene therapy based on chimeric antigen receptors: "Are we nearly there yet?" Hum. Gene Ther. 20, 1229-1239.
    • (2009) Hum. Gene Ther. , vol.20 , pp. 1229-1239
    • Dotti, G.1    Savoldo, B.2    Brenner, M.3
  • 30
    • 0036494443 scopus 로고    scopus 로고
    • Combination of T-cell therapy and trigger of inflammation induces remodeling of the vasculature and tumor eradication
    • Ganss, R., Ryschich, E., Klar, E., Arnold, B., and Hammerling, G.J. (2002). Combination of T-cell therapy and trigger of inflammation induces remodeling of the vasculature and tumor eradication. Cancer Res. 62, 1462-1470.
    • (2002) Cancer Res. , vol.62 , pp. 1462-1470
    • Ganss, R.1    Ryschich, E.2    Klar, E.3    Arnold, B.4    Hammerling, G.J.5
  • 34
    • 76049089546 scopus 로고    scopus 로고
    • Cytokine stimulation and the choice of promoter are critical factors for the efficient transduction of mouse T cells with HIV-1 vectors
    • Gilham, D.E., Lie, A.L.M., Taylor, N., and Hawkins, R.E. (2010). Cytokine stimulation and the choice of promoter are critical factors for the efficient transduction of mouse T cells with HIV-1 vectors. J. Gene Med. 12, 129-136.
    • (2010) J. Gene Med. , vol.12 , pp. 129-136
    • Gilham, D.E.1    Lie, A.L.M.2    Taylor, N.3    Hawkins, R.E.4
  • 46
    • 33749137954 scopus 로고    scopus 로고
    • Combination of vaccination and chimeric receptor expressing T cells provides improved active therapy of tumors
    • Jiang, H.R., Gilham, D.E., Mulryan, K., Kirillova, N., Hawkins, R.E., and Stern, P.L. (2006). Combination of vaccination and chimeric receptor expressing T cells provides improved active therapy of tumors. J. Immunol. 177, 4288-4298.
    • (2006) J. Immunol. , vol.177 , pp. 4288-4298
    • Jiang, H.R.1    Gilham, D.E.2    Mulryan, K.3    Kirillova, N.4    Hawkins, R.E.5    Stern, P.L.6
  • 47
    • 68449096174 scopus 로고    scopus 로고
    • Genetic modification of T cells with IL-21 enhances antigen presentation and generation of central memory tumor-specific cyto-toxic T-lymphocytes
    • Kaka, A.S., Shaffer, D.R., Hartmaier, R., Leen, A.M., Lu, A., Bear, A., Rooney, C.M., and Foster, A.E. (2009). Genetic modification of T cells with IL-21 enhances antigen presentation and generation of central memory tumor-specific cyto-toxic T-lymphocytes. J. Immunother. 32, 726-736.
    • (2009) J. Immunother. , vol.32 , pp. 726-736
    • Kaka, A.S.1    Shaffer, D.R.2    Hartmaier, R.3    Leen, A.M.4    Lu, A.5    Bear, A.6    Rooney, C.M.7    Foster, A.E.8
  • 49
    • 70349256199 scopus 로고    scopus 로고
    • Making and circumventing tolerance to cancer
    • Kammertoens, T., and Blankenstein, T. (2009). Making and circumventing tolerance to cancer. Eur. J. Immunol. 39, 2345-2353.
    • (2009) Eur. J. Immunol. , vol.39 , pp. 2345-2353
    • Kammertoens, T.1    Blankenstein, T.2
  • 56
    • 42649085033 scopus 로고    scopus 로고
    • Non-myeloablative chemotherapy followed by T-cell adoptive transfer and dendritic cell-based vaccination results in rejection of established melanoma
    • Koike, N., Pilon-Thomas, S., and Mule, J.J. (2008). Non-myeloablative chemotherapy followed by T-cell adoptive transfer and dendritic cell-based vaccination results in rejection of established melanoma. J. Immunother. 31, 402-412.
    • (2008) J. Immunother. , vol.31 , pp. 402-412
    • Koike, N.1    Pilon-Thomas, S.2    Mule, J.J.3
  • 57
    • 67650302839 scopus 로고    scopus 로고
    • Regulatory aspects for translating gene therapy research into the clinic
    • Laurencot, C.M., and Ruppel, S. (2009). Regulatory aspects for translating gene therapy research into the clinic. Methods Mol. Biol. 542, 397-421.
    • (2009) Methods Mol. Biol. , vol.542 , pp. 397-421
    • Laurencot, C.M.1    Ruppel, S.2
  • 59
    • 33746102229 scopus 로고    scopus 로고
    • Comparison of common g-chain cytokines, interleukin-2, interleukin-7, and interleukin-15 for the in vitro generation of human tumor-reactive T lymphocytes for adoptive cell transfer therapy
    • Liu, S., Riley, J., Rosenberg, S., and Parkhurst, M. (2006). Comparison of common g-chain cytokines, interleukin-2, interleukin-7, and interleukin-15 for the in vitro generation of human tumor-reactive T lymphocytes for adoptive cell transfer therapy. J. Immunother. 29, 284-293.
    • (2006) J. Immunother. , vol.29 , pp. 284-293
    • Liu, S.1    Riley, J.2    Rosenberg, S.3    Parkhurst, M.4
  • 60
    • 49049107410 scopus 로고    scopus 로고
    • IL-15 serves as a costimulator in determining the activity of autoreactive CD8 T cells in an experimental mouse model of graft-versus-host- like disease
    • Miyagawa, F., Tagaya, Y., Kim, B.S., Patel, H.J., Ishida, K., Ohteki, T., Waldmann, T.A., and Katz, S.I. (2008). IL-15 serves as a costimulator in determining the activity of autoreactive CD8 T cells in an experimental mouse model of graft-versus-host-like disease. J. Immunol. 181, 1109-1119.
    • (2008) J. Immunol. , vol.181 , pp. 1109-1119
    • Miyagawa, F.1    Tagaya, Y.2    Kim, B.S.3    Patel, H.J.4    Ishida, K.5    Ohteki, T.6    Waldmann, T.A.7    Katz, S.I.8
  • 63
    • 0030748995 scopus 로고    scopus 로고
    • Cyclophos-phamide-induced bacterial translocation in Escherichia coli C25-monoassociated specific pathogen-free mice
    • Nakayama, M., Itoh, K., and Takahashi, E. (1997). Cyclophos-phamide- induced bacterial translocation in Escherichia coli C25-monoassociated specific pathogen-free mice. Microbiol. Immunol. 41, 587-593.
    • (1997) Microbiol. Immunol. , vol.41 , pp. 587-593
    • Nakayama, M.1    Itoh, K.2    Takahashi, E.3
  • 65
    • 0042591416 scopus 로고    scopus 로고
    • Synergy between chemotherapy and immunotherapy in the treatment of established murine solid tumors
    • Nowak, A.K., Robinson, B.W., and Lake, R.A. (2003). Synergy between chemotherapy and immunotherapy in the treatment of established murine solid tumors. Cancer Res. 63, 4490-4496.
    • (2003) Cancer Res. , vol.63 , pp. 4490-4496
    • Nowak, A.K.1    Robinson, B.W.2    Lake, R.A.3
  • 66
    • 65249138393 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells: Linking inflammation and cancer
    • Ostrand-Rosenberg, S., and Sinha, P. (2009). Myeloid-derived suppressor cells: Linking inflammation and cancer. J. Immunol. 182, 4499-4506.
    • (2009) J. Immunol. , vol.182 , pp. 4499-4506
    • Ostrand-Rosenberg, S.1    Sinha, P.2
  • 72
    • 74549216531 scopus 로고    scopus 로고
    • Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells
    • Pipkin, M.E., Sacks, J.A., Cruz-Guilloty, F., Lichtenheld, M.G., Bevan, M.J., and Rao, A. (2010). Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells. Immunity 32, 79-90.
    • (2010) Immunity , vol.32 , pp. 79-90
    • Pipkin, M.E.1    Sacks, J.A.2    Cruz-Guilloty, F.3    Lichtenheld, M.G.4    Bevan, M.J.5    Rao, A.6
  • 73
    • 0016314602 scopus 로고
    • Reversal of immunological tolerance by cyclophosphamide through inhibition of suppressor cell activity
    • Polak, L., and Turk, J.L. (1974). Reversal of immunological tolerance by cyclophosphamide through inhibition of suppressor cell activity. Nature 249, 654-656.
    • (1974) Nature , vol.249 , pp. 654-656
    • Polak, L.1    Turk, J.L.2
  • 74
    • 77950603634 scopus 로고    scopus 로고
    • TCR gene-engineered T cell: Limited T cell activation and combined use of IL-15 and IL-21 ensure minimal differentiation and maximal antigen-specificity
    • 2010 Mar 17. [Epub ahead of print]
    • Pouw, N., Treffers-Westerlaken, E., Mondino, A., Lamers, C., and Debets, R. (2010) TCR gene-engineered T cell: Limited T cell activation and combined use of IL-15 and IL-21 ensure minimal differentiation and maximal antigen-specificity. Mol. Immunol. 2010 Mar 17. [Epub ahead of print].
    • (2010) Mol. Immunol
    • Pouw, N.1    Treffers-Westerlaken, E.2    Mondino, A.3    Lamers, C.4    Debets, R.5
  • 75
    • 54349103005 scopus 로고    scopus 로고
    • Adoptive T-cell therapy for malignant disorders
    • Powell, D.J., Jr., and Levine, B.L. (2008). Adoptive T-cell therapy for malignant disorders. Haematologica 93, 1452-1456.
    • (2008) Haematologica , vol.93 , pp. 1452-1456
    • Powell Jr., D.J.1    Levine, B.L.2
  • 79
    • 0035902080 scopus 로고    scopus 로고
    • Progress in human tumour immunology and immunotherapy
    • Rosenberg, S.A. (2001). Progress in human tumour immunology and immunotherapy. Nature 411, 380-384.
    • (2001) Nature , vol.411 , pp. 380-384
    • Rosenberg, S.A.1
  • 80
    • 67651096055 scopus 로고    scopus 로고
    • Regulation of T cell-dendritic cell interactions by IL-7 governs T-cell activation and homeostasis
    • Saini, M., Pearson, C., and Seddon, B. (2009). Regulation of T cell-dendritic cell interactions by IL-7 governs T-cell activation and homeostasis. Blood 113, 5793-5800.
    • (2009) Blood , vol.113 , pp. 5793-5800
    • Saini, M.1    Pearson, C.2    Seddon, B.3
  • 82
    • 61449258305 scopus 로고    scopus 로고
    • Recovery from cyclophosphamide-induced lympho-penia results in expansion of immature dendritic cells which can mediate enhanced prime-boost vaccination antitumor responses in vivo when stimulated with the TLR3 agonist poly(I:C
    • Salem, M.L., Diaz-Montero, C.M., Al-Khami, A.A., El-Naggar, S.A., Naga, O., Montero, A.J., Khafagy, A., and Cole, D.J. (2009). Recovery from cyclophosphamide-induced lympho-penia results in expansion of immature dendritic cells which can mediate enhanced prime-boost vaccination antitumor responses in vivo when stimulated with the TLR3 agonist poly(I:C). J. Immunol. 182, 2030-2040.
    • (2009) J. Immunol. , vol.182 , pp. 2030-2040
    • Salem, M.L.1    Diaz-Montero, C.M.2    Al-Khami, A.A.3    El-Naggar, S.A.4    Naga, O.5    Montero, A.J.6    Khafagy, A.7    Cole, D.J.8
  • 83
    • 77949889975 scopus 로고    scopus 로고
    • Cyclophosphamide induces dynamic alterations in the host microenvironments resulting in a Flt3 ligand-dependent expansion of dendritic cells
    • Salem, M.L., Al-Khami, A.A., El-Naggar, S.A., Diaz-Montero, C.M., Chen, Y., and Cole, D.J. (2010). Cyclophosphamide induces dynamic alterations in the host microenvironments resulting in a Flt3 ligand-dependent expansion of dendritic cells. J. Immunol. 184, 1737-1747.
    • (2010) J. Immunol. , vol.184 , pp. 1737-1747
    • Salem, M.L.1    Al-Khami, A.A.2    El-Naggar, S.A.3    Diaz-Montero, C.M.4    Chen, Y.5    Cole, D.J.6
  • 84
    • 70249100293 scopus 로고    scopus 로고
    • \+ memory T cells: Functional modules for tailored immunity
    • \+ memory T cells: Functional modules for tailored immunity. Eur. J. Immunol. 39, 2076-2082.
    • (2009) Eur. J. Immunol. , vol.39 , pp. 2076-2082
    • Sallusto, F.1    Lanzavecchia, A.2
  • 85
    • 0034332403 scopus 로고    scopus 로고
    • Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo
    • Schluns, K.S., Kieper, W.C., Jameson, S.C., and Lefrancois, L. (2000). Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nat. Immunol. 1, 426-432.
    • (2000) Nat. Immunol. , vol.1 , pp. 426-432
    • Schluns, K.S.1    Kieper, W.C.2    Jameson, S.C.3    Lefrancois, L.4
  • 88
    • 0036786514 scopus 로고    scopus 로고
    • TCR and IL-7 receptor signals can operate independently or synergize to promote lymphopenia-induced expansion of naive T cells
    • Seddon, B., and Zamoyska, R. (2002a). TCR and IL-7 receptor signals can operate independently or synergize to promote lymphopenia-induced expansion of naive T cells. J. Immunol. 169, 3752-3759.
    • (2002) J. Immunol. , vol.169 , pp. 3752-3759
    • Seddon, B.1    Zamoyska, R.2
  • 89
    • 0037105615 scopus 로고    scopus 로고
    • TCR signals mediated by Src family kinases are essential for the survival of naive T cells
    • Seddon, B., and Zamoyska, R. (2002b). TCR signals mediated by Src family kinases are essential for the survival of naive T cells. J. Immunol. 169, 2997-3005.
    • (2002) J. Immunol. , vol.169 , pp. 2997-3005
    • Seddon, B.1    Zamoyska, R.2
  • 90
    • 73849138583 scopus 로고    scopus 로고
    • Perspective on potential clinical applications of recombinant human interleukin-7
    • Sportes, C., Gress, R.E., and Mackall, C.L. (2009). Perspective on potential clinical applications of recombinant human interleukin-7. Ann. N.Y. Acad. Sci. 1182, 28-38.
    • (2009) Ann. N.Y. Acad. Sci. , vol.1182 , pp. 28-38
    • Sportes, C.1    Gress, R.E.2    MacKall, C.L.3
  • 92
    • 0034698825 scopus 로고    scopus 로고
    • Homeostatic T cell proliferation: How far can T cells be activated to self-ligands?
    • Surh, C.D., and Sprent, J. (2000). Homeostatic T cell proliferation: How far can T cells be activated to self-ligands? J. Exp. Med. 192, F9-F14.
    • (2000) J. Exp. Med. , vol.192
    • Surh, C.D.1    Sprent, J.2
  • 93
    • 67651173217 scopus 로고    scopus 로고
    • Radiotherapy combined with intratumoral dendritic cell vaccination enhances the therapeutic efficacy of adoptive T-cell transfer
    • Teitz-Tennenbaum, S., Li, Q., Davis, M.A., Wilder-Romans, K., Hoff, J., Li, M., and Chang, A.E. (2009). Radiotherapy combined with intratumoral dendritic cell vaccination enhances the therapeutic efficacy of adoptive T-cell transfer. J. Immun-other. 32, 602-612.
    • (2009) J. Immun-other. , vol.32 , pp. 602-612
    • Teitz-Tennenbaum, S.1    Li, Q.2    Davis, M.A.3    Wilder-Romans, K.4    Hoff, J.5    Li, M.6    Chang, A.E.7
  • 96
    • 55949105361 scopus 로고    scopus 로고
    • Adjuvants targeting innate and adaptive immunity synergize to enhance tumor immunotherapy
    • Verdeil, G., Marquardt, K., Surh, C.D., and Sherman, L.A. (2008). Adjuvants targeting innate and adaptive immunity synergize to enhance tumor immunotherapy. Proc. Natl. Acad. Sci. U.S.A. 105, 16683-16688.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 16683-16688
    • Verdeil, G.1    Marquardt, K.2    Surh, C.D.3    Sherman, L.A.4
  • 97
    • 0037443424 scopus 로고    scopus 로고
    • IL-7 surface-engineered lentiviral vectors promote survival and efficient gene transfer in resting primary T lymphocytes
    • Verhoeyen, E., Dardalhon, V., Ducrey-Rundquist, O., Trono, D., Taylor, N., and Cosset, F.L. (2003). IL-7 surface-engineered lentiviral vectors promote survival and efficient gene transfer in resting primary T lymphocytes. Blood 101, 2167-2174.
    • (2003) Blood , vol.101 , pp. 2167-2174
    • Verhoeyen, E.1    Dardalhon, V.2    Ducrey-Rundquist, O.3    Trono, D.4    Taylor, N.5    Cosset, F.L.6
  • 98
    • 0034662114 scopus 로고    scopus 로고
    • Cyclophosphamide enhances anti-tumor effect of wild-type p53-specific CTL
    • Vierboom, M.P., Bos, G.M., Ooms, M., Offringa, R., and Melief, C.J. (2000). Cyclophosphamide enhances anti-tumor effect of wild-type p53-specific CTL. Int. J. Cancer 87, 253-260.
    • (2000) Int. J. Cancer , vol.87 , pp. 253-260
    • Vierboom, M.P.1    Bos, G.M.2    Ooms, M.3    Offringa, R.4    Melief, C.J.5
  • 99
    • 65449185003 scopus 로고    scopus 로고
    • Novel function for interleukin-7 in dendritic cell development
    • Vogt, T.K., Link, A., Perrin, J., Finke, D., and Luther, S.A. (2009). Novel function for interleukin-7 in dendritic cell development. Blood 113, 3961-3968.
    • (2009) Blood , vol.113 , pp. 3961-3968
    • Vogt, T.K.1    Link, A.2    Perrin, J.3    Finke, D.4    Luther, S.A.5
  • 101
    • 34548083370 scopus 로고    scopus 로고
    • Enhancing immune responses for cancer therapy
    • Xue, S.A., and Stauss, H.J. (2007). Enhancing immune responses for cancer therapy. Cell. Mol. Immunol. 4, 173-184.
    • (2007) Cell. Mol. Immunol. , vol.4 , pp. 173-184
    • Xue, S.A.1    Stauss, H.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.