Evaluation of antioxidant and antiulcer potential of cucumis Sativum L. Seed extract in rats

Asian Journal of Clinical Nutrition

Volumn 1, Issue 3, 2009, Pages 131-138

  Gill, N S ^a   Garg, M ^a   Bansal, R ^a   Sood, S ^a   Muthuraman, A ^a   Bali, M ^a   Sharma, P D ^b  

^a I K GUJRAL PUNJAB TECHNICAL UNIVERSITY   (India)

^b PANJAB UNIVERSITY   (India)

Author keywords

Antiulcer; Cucumis sativum; Pylorus ligation; Water immersion stress

Indexed keywords

CUCUMIS; RATTUS; SATIVUM;

EID: 77951962562     PISSN: 19921470     EISSN: None     Source Type: Journal    
DOI: 10.3923/ajcn.2009.131.138     Document Type: Article

References (29)

1. Allison, A.J., D.N. Butcher, J.D. Conolley andK.H. Overton, 1968. Pamculides A, B and C, bisabolenoid lactones from tissue cultures of Andrographis paniculata. Chem. Commun., 23: 1493-1493.
2. Arora, A. andM.P. Sharma, 1990. Use of banana in nonulcer dyspepsia. Lancet, 335: 612-613.
3. Bose, M., V.M. Motghare, G.N. Dakhale and A.V. Turankar, 2003. Antiulcer activity of levcromakalim and nicorandil in albino study. Pol. J. Pharmacol., 55: 91-95.
4. Chaturvedi, A., M. Kumar, G. Hawani, H. Chaturvedi andR.K. Goel, 2007. Effect of ethanoic extract of Eugenia jamolana seeds on gastric ulceration and secretion in rats. Indian J. Physiol. Pharmacol., 51: 131-140.
5. Das, S., S. Deka and K. Gohain, 2008. A prechnical study on the gastric ulcer protective activity of the world s hottest chilli, Capsicum frutescenes. J. Clin. Dia. Res., 2: 1024-1027.
6. Delbert, D.H., L.R. Baker andH.M. Sell, 1972. Isolation and identification of the gibberellins from cucumis sativus and cucumis melo. Planta, 103: 241-248.
7. Disi, A.M., S.O. Tamimi and G.M. Abuereish, 1998. Effects of anchusa strigosa root aqueous extract on gastric ethanol-induced ulcer in laboratory animals. J. Ethnopharmacol, 60: 189-198.
8. Ehsabetsky, E. and L. Costa-Campos, 1996. Medicinal plant genetic resources and international cooperation: The brazilian perspective. J. Ethnopharmacol, 51: 111-119.
9. Falcao, H.S., LA. Leite, J.M. Barbosa-Filho, F.P. Athayde-Filho and M.C.O. Chaves et al, 2008. Gastric and duodenal antiulcer activity of alkaloids. Molecules, 13: 3198-3223.
10. Goel, R.K. and S.K. Bhattacharya, 1991. Gastro duodenal mucosal defense and mucosal protective agents. Indian. J. Exp. Biol, 29: 701-714.
11. Goel, R.K. andK. Sairam, 2002. Antiulcer drugs from indigenous sources with emphasis on Musa sapientum, Tamrabhasna, Asparagus racemosus and Zingiber officinale. Ind. J. Pharmacol, 34: 100-110.
12. Goswani, S., S. Jain and D. Santani, 1997. Antiulcer activity of cromakalim against experimentally induced gastric and duodenal ulcers in rats and guinea pigs. J. Pharm. Pharmacol, 49: 195-199.
13. Halliwell, B., 1981. The biological effects of the superoxide radical and its products. Bull. Eur. Physiopathol. Respir., 17: 21-29.
14. Harborne, J.B., 1973. Phytochemical Methods. Chapman and Hall, Ltd., London, pp: 49-188.
15. Ivy, K.M., 1988. Mechanisms of nonsteroidal antiinflammatory drug-induced gastric damage: Actions of therapeutic agents. Am. J. Med., 84: 41-48.
16. Kaplan, M.A.C. and O.R. Gottlieb, 1990. Busca racional de principios ativos em plantas. Interciencia, 15: 26-29.
17. Khayum, M.A., K. Nandakumar, T.S. Gouda, S.M. Khalid, V.N. Rao and S.M.S. Kumar, 2009. Antiulcer activity of stem extracts of Tinospora malabarica (Lamk.). Pharmacologyonline, 1: 885-890.
18. Kitagawa, H., M. Fujiwara and Y. Osumi, 1979. Effect of water immersion stress on gastric secretion and mucosal blood flow in rats. Gastroenterology, 77: 298-302.
19. Malairajan, P., G. Gopalkrishana, S. Narasimhan and K.J. kala-Veni, 2008. Evaluation of antiulcer activity of polyalthia longifolia (Sonn.). Indian. J. Pharmacol., 40: 126-128.
20. Mohammad, S.A., 2009. Lupeol, novel anti-inflammatory and anti-cancer dietary triterpene. Can. Lett., 285: 109-115.
21. Muralidharan, P. and J. Srikanth, 2009. Antiulcer activity of Morinda citrifolia Linn fruit extract. J. Sci. Res., 1: 345-352.
22. Parmar,N.S. and J.K. Desai, 1993. Areview ofthe current methodology for the evaluation of gastric and duodenal antiulcer agents. Indian. J. Pharmacol, 25: 120-135.
23. Paul, A., S. Goswami and D. Santani, 2004. Gastroprotective effects of a3-adrenoceptor agonists on water immersion plus restraint stress-induced gastric ulcer in rats. Indian. J. Pharmacol, 36: 151-154.
24. Rajkapoor, B., R. Anandan and B. Jayakar, 2002. Antiulcer effect of Nigella sativa Linn. against gastric ulcer in rats. Current Sci., 82: 177-179.
25. Shay, H., S.A. Komarov, S.E. Fels, D. Meraze, M. Gruenstein and H. Siplet, 1945. A simple method for the uniform production of gastric ulceration in the rat. Gastroenterology, 5: 43-61.
26. Singh, S., A. Khajuna, S.C. Taneja, R.K. Khajuria, J, Singh, R.K. John and G.N. Qazi, 2008. The gastric ulcer protective effect of boswellic acids, a leukotriene inhibitor from Boswellia serrata, in rats. Phytomedicine, 15: 408-415.
27. Takagi, K., S. Okabe and R. Saziki, 1969. A new method for the production of chronic gastric ulcer in rats and the effect of several drugs on its healing. Jpn. Pharmacol., 19: 418-426.
28. William, M.W., B.R. Svhadel and W.E. Schadel, 1991. Wound healing in cucumber fruits. J. Am. Soc. Hort. Sci., 115: 444-452.
29. Yuan, Y., I.T. Padol and R.H. Hunt, 2006. Peptic ulcer disease today. Nat. Clin. Pract. Gastroenterol Hepatol., 3: 80-89.