Does hereditary hemochromatosis influence the age of onset of Huntington's disease?

Movement Disorders

Volumn 25, Issue 7, 2010, Pages 946-

  Walker, Francis O ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALLELE; BEHAVIOR CHANGE; CASE REPORT; COGNITIVE DEFECT; CONFUSION; FEMALE; FINGER; HEMOCHROMATOSIS; HEREDITARY HEMOCHROMATOSIS; HEREDITY; HUMAN; HUNTINGTON CHOREA; INVOLUNTARY MOVEMENT; LABORATORY TEST; LETTER; MENTAL INSTABILITY; MUTATION; ONSET AGE; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL;

AGE OF ONSET; FEMALE; HEMOCHROMATOSIS; HUMANS; HUNTINGTON DISEASE; MIDDLE AGED; TRINUCLEOTIDE REPEATS;

EID: 77951948158     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.22695     Document Type: Letter

References (7)

1. Walker FO. Huntington's disease. Lancet 2007;369:218-228.
2. Langbehn DR, Brinkman RR, Falush D, Paulsen JS. A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length. Clin Genet 1994;65:267-277.
3. Schrier SL, Bacon BR. Genetics of hereditary hemochromatosis. Available at UptoDate.com (accessed January 5, 2009).
4. Bartzokis G, Cummings J, Perlman S, Hance DB, Mintz J. Increased basal ganglia iron levels in Huntington's disease. Arch Neurol 1999;56:569-574. (Pubitemid 29218152)
5. Simmons DA, Casale M, Alcon B, Pham N, Narayan N, Lynch G. Ferritin accumulation in dystrophic microglia is an early event in the development of Huntington's disease. Glia 2007;55:1074-1084. (Pubitemid 47066747)
6. Lawless MW, Mankan AK, Norris S. Hereditary hemochromatosis should be considered a conformational disorder. Med Hyoptheses 2008;70:783-784. (Pubitemid 351324849)
7. Russo N, Edwards M, Andres T, O'Brien M, Bhatia KP. Hereditary haemochromatosis is unlikely to cause movement disorders - a critical review. J Neurol 2004;251:849-852. (Pubitemid 39005970)