Using monte-carlo-simulated radiation transport to calculate dose distribution in rats before irradiation with leksell gamma knife® 4c: Technical note

Stereotactic and Functional Neurosurgery

Volumn 88, Issue 4, 2010, Pages 208-215

  Marcelin, Béatrice ^a   Kjäll, Per ^c   Johansson, Jonas ^c   Lundin, Anders ^c   Nordström, Håkan ^c   Eriksson, Markus ^c   Bernard, Christophe ^a   Régis, Jean ^a,b  

^a INSERM   (France)

^b TIMONE HOSPITAL   (France)

^c Elekta AB   (Sweden)

Author keywords

Epilepsy; Leksell Gamma Knife ; Leksell GammaPlan ; Monte Carlo simulation

Indexed keywords

ACCURACY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN SIZE; COLLIMATOR; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DOSE CALCULATION; ENERGY; GAMMA KNIFE RADIOSURGERY; HIPPOCAMPUS; IRRADIATION; MONTE CARLO METHOD; NONHUMAN; OUTCOME ASSESSMENT; PREDICTION; QUANTITATIVE ANALYSIS; RADIATION DOSE DISTRIBUTION; RADIATION RESPONSE; RAT; TEMPORAL LOBE EPILEPSY; THERMOLUMINESCENCE DOSIMETER; TISSUE SPECIFICITY; TREATMENT PLANNING; ANIMAL; CALIBRATION; COMPUTER ASSISTED RADIOTHERAPY; DEVICES; PROCEDURES; RADIATION DOSE; RADIOSURGERY;

ANIMALS; CALIBRATION; RADIATION DOSAGE; RADIOSURGERY; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RATS;

EID: 77951947493     PISSN: 10116125     EISSN: None     Source Type: Journal    
DOI: 10.1159/000314355     Document Type: Article

References (23)

1. Romanelli P, Anschel DJ: Radiosurgery for epilepsy. Lancet Neurol 2006; 5: 613-620.
2. Mattson RH, Cramer JA, Collins JF: Prognosis for total control of complex partial and secondarily generalized tonic clonic seizures. Department of Veterans Affairs Epilepsy Cooperative Studies No.118 and No. 264 Group. Neurology 1996; 47: 68-76.
3. Löscher W, Potschka H: Role of multidrug transporters in pharmacoresistance to antiepileptic drugs. J Pharmacol Exp Ther 2002; 301: 7-14.
4. Ojemann GA: Treatment of temporal lobe epilepsy. Annu Rev Med 1997; 48: 317-328.
5. Régis J, Bartolomei F, Hayashi M, Chauvel P: Gamma knife surgery, a neuromodulation therapy in epilepsy surgery! Acta Neurochir Suppl 2002; 84: 37-47.
6. Régis J, Rey M, Bartolomei F, Vladyka V, Liscak R, Schröttner O, Pendl G: Gamma knife surgery in mesial temporal lobe epilepsy: a prospective multicenter study. Epilepsia 2004; 45: 504-515.
7. Régis J, Kerkerian-Legoff L, Rey M, Vial M, Porcheron D, Nieoullon A, Peragut JC: First biochemical evidence of differential functional effects following gamma knife surgery. Stereotact Funct Neurosurg 1996; 66(suppl 1):29-38.
8. Mori Y, Kondziolka D, Balzer J, Fellows W, Flickinger JC, Lunsford LD, Thulborn KR: Effects of stereotactic radiosurgery on an animal model of hippocampal epilepsy. Neurosurgery 2000; 46: 157-165, discussion 165-168.
9. Maesawa S, Kondziolka D, Dixon CE, Balzer J, Fellows W, Lunsford LD: Subnecrotic stereotactic radiosurgery controlling epilepsy produced by kainic acid injection in rats. J Neurosurg 2000; 93: 1033-1040.
10. Chen ZF, Kamiryo T, Henson SL, Yamamoto H, Bertram EH, Schottler F, Patel F, Steiner L, Prasad D, Kassell NF, Shareghis S, Lee KS: Anticonvulsant effects of gamma surgery in a model of chronic spontaneous limbic epilepsy in rats. J Neurosurg 2001; 94: 270-280.
11. Novotný J Jr, Novotný J, Spváek V, Dvoák P, Echák T, Lisák R, Brozek G, Tintra J, Vymazal J: Evaluation of geometric and dosimetric inaccuracies of stereotactic irradiation in the rat brain. Stereotact Funct Neurosurg 2002; 79: 57-74.
12. Paxinos G, Watson C: The Rat Brain in Stereotaxic Coordinates, ed 4. San Diego, Academic Press, 1998.
13. Rey M, Valliccioni PA, Vial M, Porcheron D, Régis J, Kerlerian-le Goff L, Nieoullon A, Millet Y, Peragut JC: Experimental radiosurgery in rats using a 'gamma knife': description of a stereotactic device for small laboratory animals (in French). Neurochirurgie 1996; 42: 289-293.
14. Salvat F, Fernández-Varea JM, Acosta E, Sempau J: Penelope, a code system for Monte Carlo simulation of electron and photon transport. Proceedings of the OECD/NEA Workshop/Training Course, Issy-les-Moulineaux, 2001.
15. Sempau J, Acosta E, Baro J, Fernández-Varea JM, Salvat F: An algorithm for Monte Carlo simulation of the coupled electron-photon transport. Nucl Instrum Methods Phys Res B 1997; 132: 377-390.
16. Sempau J, Fernández-Varea JM, Acosta E, Salvat F: Experimental benchmarks of the Monte Carlo code Penelope. Nucl Instrum Methods Phys Res B 2003; 207: 107-123.
17. Salvat F, Fernández-Varea JM, Sempau J: Penelope - 2006: a code system for Monte Carlo simulation of electron and photon transport. Proceedings of the OECD/NEA Workshop, Pisa, 2006.
18. Lundin A, Nordström H, Johansson J, Eriksson M, Kjäll P: A versatile and user-friendly Monte Carlo simulation system designed for complex geometries. Phys Med Biol, in preparation.
19. Kamiryo T, Berk HW, Lee KS, Kassell NF, Steiner L: A stereotactic device for experimental gamma knife radiosurgery in rats: a technical note. Acta Neurochir (Wien) 1993; 125: 156-160.
20. Buzsaki G: Theta oscillations in the hippocampus. Neuron 2002; 33: 325-340.
21. Régis J, Levivier M, Hayashi M: Radiosurgery for intractable epilepsy. Tech Neurosurg 2003; 9: 191-203.
22. Vojtech Z, Vladyka V, Kalina M, Nespor E, Seltenreichová K, Semnická J, Lisák R: The use of radiosurgery for the treatment of mesial temporal lobe epilepsy and long-term results. Epilepsia 2009; 50: 2061-2071.
23. Barbaro NM, Quigg M, Broshek DK, Ward MM, Lamborn KR, Laxer KD, Larson DA, Dillon W, Verhey L, Garcia P, Steiner L, Heck C, Kondziolka D, Beach R, Olivero W, Witt TC, Salanova V, Goodman R: A multicenter, prospective pilot study of gamma knife radiosurgery for mesial temporal lobe epilepsy: seizure response, adverse events, and verbal memory. Ann Neurol 2009; 65: 167-175.