Consolidation of evidence for association of the kiaa1109-tenr-il2-il21 rs6822844 variant with crohn's disease

American Journal of Gastroenterology

Volumn 105, Issue 5, 2010, Pages 1204-1206

  Hollis Moffatt, Jade E ^a   Gearry, Richard B ^b,c   Barclay, Murray L ^b,c   Merriman, Tony R ^a   Roberts, Rebecca L ^a,b  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b UNIVERSITY OF OTAGO   (New Zealand)

^c CHRISTCHURCH HOSPITAL   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 2; INTERLEUKIN 21;

ALLELE; CAUCASIAN; CROHN DISEASE; GENE; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; IL2 GENE; IL21 GENE; INFLAMMATORY DISEASE; LETTER; PHENOTYPE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; ULCERATIVE COLITIS;

ALLELES; COHORT STUDIES; CROHN DISEASE; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; INTERLEUKIN-2; INTERLEUKINS; MALE; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; SENSITIVITY AND SPECIFICITY;

EID: 77951941072     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1038/ajg.2010.34     Document Type: Letter

References (4)

1. Glas J, Stallhofer J, Ripke S et al. Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease. Am J Gastroenterol 2009; 104: 1737-1744
2. Festen EA, Goyette P, Scott R et al. Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis. Gut 2009; 58: 799-804.
3. Marquez A, Orozco G, Martinez A et al. Novel association of the interleukin 2-interleukin 21 region with infl ammatory bowel disease. Am J Gastroenterol 2009; 104: 1968-1975
4. Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447: 661-678