Efficient siRNA delivery by novel PTD-DRBD fusion proteins

Cell Cycle

Volumn 9, Issue 3, 2010, Pages 424-425

  Eguchi, Akiko ^a   Dowdy, Steven F ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

PTD DRBD; RNAi; siRNA delivery; TAT peptide transduction domain

Indexed keywords

ALPHA INTERFERON; CELL PENETRATION PEPTIDE; DOUBLE STRANDED RNA; HYBRID PROTEIN; MESSENGER RNA; PEPTIDE; SMALL INTERFERING RNA; TRANSCRIPTOME; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; CANCER GENE THERAPY; CELL CYCLE; CELL TYPE; CYTOPLASM; CYTOTOXICITY; DRUG SELECTIVITY; EDITORIAL; ENDOTHELIUM CELL; ESCHERICHIA COLI; GENE DELIVERY SYSTEM; GLIOBLASTOMA; HUMAN; INNATE IMMUNITY; NONHUMAN; PINOCYTOSIS; PRECIPITATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA BINDING; RNA INTERFERENCE; TUMOR CELL; CELL LINE; CHEMISTRY; GENE TRANSFER; METABOLISM; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE;

CELL LINE; GENE TRANSFER TECHNIQUES; HUMANS; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; RNA INTERFERENCE; RNA, DOUBLE-STRANDED; RNA, SMALL INTERFERING;

EID: 77951934879     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.9.3.10693     Document Type: Editorial

References (7)

1. Fire A, et al. Nature 1998; 391:744-5.
2. Rana TM. Nat Rev Mol Cell Biol 2007; 8:23-36.
3. Eguchi A, et al. Trends Pharmacol Sci 2009; 30:341-5.
4. Gump JM, et al. Trends Mol Med 2007; 13:443-8.
5. Ryter JM, Schulktz S. EMBO J 1998; 17:7505-13.
6. Eguchi A, et al. Nat Biotechnol 2009; 27:567-71.
7. Michiue H, et al. Cancer Biol Ther 2009; in press.