-
1
-
-
33645526144
-
Cancer statistics, 2006
-
Jemal A, Siegel R, Ward E, Murray T, Xu J, Smigal C, Thun MJ (2006) Cancer statistics, 2006. CA Cancer J Clin 56:106-130
-
(2006)
CA Cancer J. Clin.
, vol.56
, pp. 106-130
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Murray, T.4
Xu, J.5
Smigal, C.6
Thun, M.J.7
-
2
-
-
19744368302
-
Cancer of the ovary
-
Cannistra SA (2004) Cancer of the ovary. N Engl J Med 351:2519-2529
-
(2004)
N Engl. J. Med.
, vol.351
, pp. 2519-2529
-
-
Cannistra, S.A.1
-
3
-
-
33845212719
-
Carcinoma of the ovary. FIGO 6th annual report on the results of treatment in gynecological cancer
-
Heintz AP, Odicino F, Maisonneuve P, Quinn MA, Benedet JL, Creasman WT, Ngan HY, Pecorelli S, Beller U (2006) Carcinoma of the ovary. FIGO 6th annual report on the results of treatment in gynecological cancer. Int J Gynaecol Obstet 95(Suppl 1):S161-S192
-
(2006)
Int. J. Gynaecol Obstet.
, vol.95
, Issue.1 SUPPL.
-
-
Heintz, A.P.1
Odicino, F.2
Maisonneuve, P.3
Quinn, M.A.4
Benedet, J.L.5
Creasman, W.T.6
Ngan, H.Y.7
Pecorelli, S.8
Beller, U.9
-
4
-
-
58049114787
-
EORTC-GCG/NCIC-CTG randomised trial comparing primary debulking surgery with neoadjuvant chemotherapy in stage IIIC-IV ovarian, fallopian tube and peritoneal cancer (OVCA)
-
Bangkok
-
Vergote IB, Tropé CG, Amant F, Kristensen GB, Sardi JE (2008) EORTC-GCG/NCIC-CTG randomised trial comparing primary debulking surgery with neoadjuvant chemotherapy in stage IIIC-IV ovarian, fallopian tube and peritoneal cancer (OVCA). In: 12th biennial meeting, International Gynecological Cancer Society (IGCS), Bangkok
-
(2008)
12th Biennial Meeting, International Gynecological Cancer Society (IGCS)
-
-
Vergote, I.B.1
Tropé, C.G.2
Amant, F.3
Kristensen, G.B.4
Sardi, J.E.5
-
5
-
-
70349332968
-
Neoadjuvant chemotherapy with carboplatin and docetaxel in advanced ovarian cancer-a prospective multicenter phase II trial (PRIMOVAR)
-
Pölcher M, Mahner S, Ortmann O, Hilfrich J, Diedrich K, Breitbach GP, Hoss C, Leutner C, Braun M, Mobus V, Karbe I, Stimmler P, Rudlowski C, Schwarz J, Kuhn W (2009) Neoadjuvant chemotherapy with carboplatin and docetaxel in advanced ovarian cancer-a prospective multicenter phase II trial (PRIMOVAR). Oncol Rep 22:605-613
-
(2009)
Oncol. Rep.
, vol.22
, pp. 605-613
-
-
Pölcher, M.1
Mahner, S.2
Ortmann, O.3
Hilfrich, J.4
Diedrich, K.5
Breitbach, G.P.6
Hoss, C.7
Leutner, C.8
Braun, M.9
Mobus, V.10
Karbe, I.11
Stimmler, P.12
Rudlowski, C.13
Schwarz, J.14
Kuhn, W.15
-
6
-
-
4944249117
-
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
-
Wilhelm SM, Carter C, Tang L, Wilkie D, McNabola A, Rong H, Chen C, Zhang X, Vincent P, McHugh M, Cao Y, Shujath J, Gawlak S, Eveleigh D, Rowley B, Liu L, Adnane L, Lynch M, Auclair D, Taylor I, Gedrich R, Voznesensky A, Riedl B, Post LE, Bollag G, Trail PA (2004) BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res 64:7099-7109
-
(2004)
Cancer Res.
, vol.64
, pp. 7099-7109
-
-
Wilhelm, S.M.1
Carter, C.2
Tang, L.3
Wilkie, D.4
McNabola, A.5
Rong, H.6
Chen, C.7
Zhang, X.8
Vincent, P.9
McHugh, M.10
Cao, Y.11
Shujath, J.12
Gawlak, S.13
Eveleigh, D.14
Rowley, B.15
Liu, L.16
Adnane, L.17
Lynch, M.18
Auclair, D.19
Taylor, I.20
Gedrich, R.21
Voznesensky, A.22
Riedl, B.23
Post, L.E.24
Bollag, G.25
Trail, P.A.26
more..
-
7
-
-
21644440921
-
Recent progress in targeting the Raf /MEK/ERK pathway with inhibitors in cancer drug discovery
-
Thompson N, Lyons J (2005) Recent progress in targeting the Raf /MEK/ERK pathway with inhibitors in cancer drug discovery. Curr Opin Pharmacol 5:350-356
-
(2005)
Curr. Opin. Pharmacol.
, vol.5
, pp. 350-356
-
-
Thompson, N.1
Lyons, J.2
-
8
-
-
33745715015
-
Targeting Raf-kinase: Molecular rationales and translational issues
-
Caraglia M, Tassone P, Marra M, Budillon A, Venuta S, Tagliaferri P (2006) Targeting Raf-kinase: molecular rationales and translational issues. Ann Oncol 17(7):vii124-vii127
-
(2006)
Ann. Oncol.
, vol.17
, Issue.7
-
-
Caraglia, M.1
Tassone, P.2
Marra, M.3
Budillon, A.4
Venuta, S.5
Tagliaferri, P.6
-
9
-
-
70249097380
-
Sorafenib for treatment of renal cell carcinoma: Final efficacy and safety results of the phase III treatment approaches in renal cancer global evaluation trial
-
Escudier B, Eisen T, Stadler WM, Szczylik C, Oudard S, Staehler M, Negrier S, Chevreau C, Desai AA, Rolland F, Demkow T, Hutson TE, Gore M, Anderson S, Hofilena G, Shan M, Pena C, Lathia C, Bukowski RM (2009) Sorafenib for treatment of renal cell carcinoma: final efficacy and safety results of the phase III treatment approaches in renal cancer global evaluation trial. J Clin Oncol 27:3312-3318
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 3312-3318
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
Szczylik, C.4
Oudard, S.5
Staehler, M.6
Negrier, S.7
Chevreau, C.8
Desai, A.A.9
Rolland, F.10
Demkow, T.11
Hutson, T.E.12
Gore, M.13
Anderson, S.14
Hofilena, G.15
Shan, M.16
Pena, C.17
Lathia, C.18
Bukowski, R.M.19
-
10
-
-
47949116252
-
Sorafenib in advanced hepatocellular carcinoma
-
Llovet JM, Ricci S, Mazzaferro V, Hilgard P, Gane E, Blanc JF, de Oliveira AC, Santoro A, Raoul JL, Forner A, Schwartz M, Porta C, Zeuzem S, Bolondi L, Greten TF, Galle PR, Seitz JF, Borbath I, Haussinger D, Giannaris T, Shan M, Moscovici M, Voliotis D, Bruix J (2008) Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 359:378-390
-
(2008)
N Engl. J. Med.
, vol.359
, pp. 378-390
-
-
Llovet, J.M.1
Ricci, S.2
Mazzaferro, V.3
Hilgard, P.4
Gane, E.5
Blanc, J.F.6
De Oliveira, A.C.7
Santoro, A.8
Raoul, J.L.9
Forner, A.10
Schwartz, M.11
Porta, C.12
Zeuzem, S.13
Bolondi, L.14
Greten, T.F.15
Galle, P.R.16
Seitz, J.F.17
Borbath, I.18
Haussinger, D.19
Giannaris, T.20
Shan, M.21
Moscovici, M.22
Voliotis, D.23
Bruix, J.24
more..
-
11
-
-
0013339315
-
Anti-tumour efficacy of the orally active raf kinase inhibitor BAY 43-9006 in human tumour xenograft models
-
Gianpaolo-Ostravage C, Carter C, Hibner B (2001) Anti-tumour efficacy of the orally active raf kinase inhibitor BAY 43-9006 in human tumour xenograft models. Proc Am Assoc Cancer Res 42:923
-
(2001)
Proc. Am. Assoc. Cancer Res.
, vol.42
, pp. 923
-
-
Gianpaolo-Ostravage, C.1
Carter, C.2
Hibner, B.3
-
12
-
-
33846206208
-
Phase II study of sorafenib (BAY 43-9006) in combination with gemcitabine in recurrent epithelial ovarian cancer: A PMH phase II consortium trial
-
Welch S, Hirte H, Schilder RJ, Elit L, Townsley C, Tinker L, Pond G, Afinec A, Wright JJ, Oza M (2006) Phase II study of sorafenib (BAY 43-9006) in combination with gemcitabine in recurrent epithelial ovarian cancer: a PMH phase II consortium trial. J Clin Oncol 24 (18 Suppl):276S
-
(2006)
J. Clin. Oncol.
, vol.24
, Issue.18 SUPPL.
-
-
Welch, S.1
Hirte, H.2
Schilder, R.J.3
Elit, L.4
Townsley, C.5
Tinker, L.6
Pond, G.7
Afinec, A.8
Wright, J.J.9
Oza, M.10
-
13
-
-
32444439875
-
Pooled safety analysis of BAY 43-9006 (sorafenib) monotherapy in patients with advanced solid tumours: Is rash associated with treatment outcome?
-
Strumberg D, Awada A, Hirte H, Clark JW, Seeber S, Piccart P, Hofstra E, Voliotis D, Christensen O, Brueckner A, Schwartz B (2006) Pooled safety analysis of BAY 43-9006 (sorafenib) monotherapy in patients with advanced solid tumours: is rash associated with treatment outcome? Eur J Cancer 42:548-556
-
(2006)
Eur. J. Cancer
, vol.42
, pp. 548-556
-
-
Strumberg, D.1
Awada, A.2
Hirte, H.3
Clark, J.W.4
Seeber, S.5
Piccart, P.6
Hofstra, E.7
Voliotis, D.8
Christensen, O.9
Brueckner, A.10
Schwartz, B.11
-
14
-
-
0024202761
-
Sample size considerations for studies comparing survival curves using historical controls
-
Dixon DO, Simon R (1988) Sample size considerations for studies comparing survival curves using historical controls. J Clin Epidemiol 41:1209-1213
-
(1988)
J. Clin. Epidemiol.
, vol.41
, pp. 1209-1213
-
-
Dixon, D.O.1
Simon, R.2
-
15
-
-
20044382799
-
Phase I clinical and pharmacokinetic study of the novel raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors
-
Strumberg D, Richly H, Hilger RA, Schleucher N, Korfee S, Tewes M, Faghih M, Brendel E, Voliotis D, Haase CG, Schwartz B, Awada A, Voigtmann R, Scheulen ME, Seeber S (2005) Phase I clinical and pharmacokinetic study of the Novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors. J Clin Oncol 23:965-972
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 965-972
-
-
Strumberg, D.1
Richly, H.2
Hilger, R.A.3
Schleucher, N.4
Korfee, S.5
Tewes, M.6
Faghih, M.7
Brendel, E.8
Voliotis, D.9
Haase, C.G.10
Schwartz, B.11
Awada, A.12
Voigtmann, R.13
Scheulen, M.E.14
Seeber, S.15
-
16
-
-
38049019119
-
Safety and anti-tumor activity of sorafenib (Nexavar) in combination with other anti-cancer agents: A review of clinical trials
-
Takimoto CH, Awada A (2008) Safety and anti-tumor activity of sorafenib (Nexavar) in combination with other anti-cancer agents: a review of clinical trials. Cancer Chemother Pharmacol 61:535-548
-
(2008)
Cancer Chemother. Pharmacol.
, vol.61
, pp. 535-548
-
-
Takimoto, C.H.1
Awada, A.2
-
17
-
-
67649909568
-
Results of a phase III, randomized, placebo-controlled study of sorafenib in combination with carboplatin and paclitaxel as second-line treatment in patients with unresectable stage III or stage IV melanoma
-
Hauschild A, Agarwala SS, Trefzer U, Hogg D, Robert C, Hersey P, Eggermont A, Grabbe S, Gonzalez R, Gille J, Peschel C, Schadendorf D, Garbe C, O'Day S, Daud A, White JM, Xia C, Patel K, Kirkwood JM, Keilholz U (2009) Results of a phase III, randomized, placebo-controlled study of sorafenib in combination with carboplatin and paclitaxel as second-line treatment in patients with unresectable stage III or stage IV melanoma. J Clin Oncol 27:2823-2830
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 2823-2830
-
-
Hauschild, A.1
Agarwala, S.S.2
Trefzer, U.3
Hogg, D.4
Robert, C.5
Hersey, P.6
Eggermont, A.7
Grabbe, S.8
Gonzalez, R.9
Gille, J.10
Peschel, C.11
Schadendorf, D.12
Garbe, C.13
O'Day, S.14
Daud, A.15
White, J.M.16
Xia, C.17
Patel, K.18
Kirkwood, J.M.19
Keilholz, U.20
more..
-
18
-
-
50349097617
-
Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: Implications for antiangiogenic drugs as chemosensitizing agents
-
Shaked Y, Henke E, Roodhart JM, Mancuso P, Langenberg MH, Colleoni M, Daenen LG, Man S, Xu P, Emmenegger U, Tang T, Zhu Z, Witte L, Strieter RM, Bertolini F, Voest EE, Benezra R, Kerbel RS (2008) Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: implications for antiangiogenic drugs as chemosensitizing agents. Cancer Cell 14:263-273
-
(2008)
Cancer Cell.
, vol.14
, pp. 263-273
-
-
Shaked, Y.1
Henke, E.2
Roodhart, J.M.3
Mancuso, P.4
Langenberg, M.H.5
Colleoni, M.6
Daenen, L.G.7
Man, S.8
Xu, P.9
Emmenegger, U.10
Tang, T.11
Zhu, Z.12
Witte, L.13
Strieter, R.M.14
Bertolini, F.15
Voest, E.E.16
Benezra, R.17
Kerbel, R.S.18
-
19
-
-
60649106195
-
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
-
Paez-Ribes M, Allen E, Hudock J, Takeda T, Okuyama H, Vinals F, Inoue M, Bergers G, Hanahan D, Casanovas O (2009) Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 15:220-231
-
(2009)
Cancer Cell.
, vol.15
, pp. 220-231
-
-
Paez-Ribes, M.1
Allen, E.2
Hudock, J.3
Takeda, T.4
Okuyama, H.5
Vinals, F.6
Inoue, M.7
Bergers, G.8
Hanahan, D.9
Casanovas, O.10
-
20
-
-
60649087564
-
Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis
-
Ebos JM, Lee CR, Cruz-Munoz W, Bjarnason GA, Christensen JG, Kerbel RS (2009) Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Cancer Cell 15:232-239
-
(2009)
Cancer Cell.
, vol.15
, pp. 232-239
-
-
Ebos, J.M.1
Lee, C.R.2
Cruz-Munoz, W.3
Bjarnason, G.A.4
Christensen, J.G.5
Kerbel, R.S.6
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