Mesenchymal stem cells do not suppress lymphoblastic leukemic cell line proliferation

Iranian Journal of Immunology

Volumn 6, Issue 4, 2009, Pages 186-194

  Niri, Neda Mousavi ^a   Jaberipour, Mansooreh ^b   Razmkhah, Mahboobeh ^b   Ghaderi, Abbas ^a,b   Habibagahi, Mojtaba ^a  

^a SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Jurkat cells; Mesenchymal stem cells; Suppression

Indexed keywords

CD14 ANTIGEN; CD34 ANTIGEN; CD45 ANTIGEN; ALCAM PROTEIN, HUMAN; CD44 PROTEIN, HUMAN; CELL SURFACE RECEPTOR; ENG PROTEIN, HUMAN; FETOPROTEIN; HERMES ANTIGEN; LEUKOCYTE ANTIGEN; NERVE CELL ADHESION MOLECULE;

ADIPOSE TISSUE CELL; ANTIGEN EXPRESSION; ARTICLE; CANCER INHIBITION; CELL ADHESION; CELL DIFFERENTIATION; CELL DIVISION; CELL FUNCTION; CELL GROWTH; CELL INTERACTION; COCULTURE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; LEUKEMIA CELL; LEUKEMIA CELL LINE; LIVER CELL; LYMPHATIC LEUKEMIA; LYMPHOCYTE PROLIFERATION; MESENCHYMAL STEM CELL; METABOLITE; PERIPHERAL BLOOD MONONUCLEAR CELL; T LYMPHOCYTE; ADIPOSE TISSUE; CELL CULTURE; CELL PROLIFERATION; CYTOLOGY; FLOW CYTOMETRY; IMMUNOLOGY; IMMUNOPHENOTYPING; METABOLISM; MONONUCLEAR CELL; PATHOLOGY; T CELL LEUKEMIA;

ADIPOSE TISSUE; ANTIGENS, CD; ANTIGENS, CD44; CELL ADHESION MOLECULES, NEURONAL; CELL PROLIFERATION; CELLS, CULTURED; COCULTURE TECHNIQUES; FETAL PROTEINS; FLOW CYTOMETRY; HUMANS; IMMUNOPHENOTYPING; JURKAT CELLS; LEUKEMIA, T-CELL; LEUKOCYTES, MONONUCLEAR; MESENCHYMAL STEM CELLS; RECEPTORS, CELL SURFACE;

EID: 77951912103     PISSN: 17351383     EISSN: 1735367X     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Friedenstein AJ, Piatetzky-Shapiro II, Petrakova KV. Osteogenesis in transplantation of bone marrow cells. J. Embryol Exp Morphol. 1966; 16:381-90.
2. Dazzi F, Ramasamy R, Glennie S, Jones SP, Roberts I. The role of mesenchymal stem cells in haemopoiesis. Blood Reviews. 2006; 2O:161-71.
3. Izadpanah R, Trygg C, Patel B, Kriedt C, Dufour J, Gimble JM, et al. Biologic properties of mesenchymal stem cells derived from bone marrow and adipose tissue. J Cell Biochem. 2006; 99:1285-97.
4. Brooke G, Cook M, Blair C, Han R, Heazlewood C, Jones B, et al. Therapeutic applications of mesenchymal stromal cells. Cell Developmental Biology. 2007; 18:846-58.
5. Buhring HJ, Battula VL, Treml S, Schewe B, Kanz L, Vogel W. Novel markers for the prospective isolation of human MSC. Ann NY Sci. 2007; 1106:262-71.
6. Silva WA Jr, Covas DT, Panepucci RA, Proto-Siqueira R, Siufi JL, Zanette DL, et al. The profile of gene expression of human marrow esenchymal stem cells. Stem Cells. 2003; 21: 661-9.
7. Uccelli A, Pistoia V, Moretta L. Mesenchymal stem cells: a new strategy for immunosuppression? Trends Immunology. 2007; 28:219-26.
8. Fibbe WE, Nauta AJ, Roelofs H. Modulation of immune responses by Mesenchymal stem cells. Ann N Y Sci. 2007; 1106:272-8.
9. Forte A, Napolitano MA, Cipollaro M, Giordano A, Cascino A, Galderisi U. An effective method for adenoviral-mediated delivery of small interfering RNA into mesenchymal stem cells. J Cell Biochem. 2007; 100:293-302.
10. Chen X, Armstrong MA, Li G. Mesenchymal stem cells in immunoregulation. Immunology Cell Biol. 2006; 84:413-21.
11. Sato Y, Araki H, Kato J, Nakamura K, Kawano Y, Kobune M, et al. Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion. Blood. 2005; 106:756-63.
12. Noort WA, Kruisselbrink AB, in't Anker PS, Kruger M, van Bezooijen RL, de Paus RA, et al. Mesenchymal stem cells pro-mote engraftment of human umbilical cord blood-derived CD34(+) cells in NOD/SCID mice. Exp Hematol. 2002; 30:870-8.
13. Zhang Y, Adachi Y, Suzuki Y, Minamino K, Iwasaki M, Hisha H, et al. Simultaneous injection of bone marrow cells and stromal cells into bone marrow accelerates hematopoiesis in vivo. Stem Cells. 2004; 22:1256-62.
14. Bartholomew A, Sturgeon C, Siatskas M, Ferrer K, McIntosh K, Patil S, et al. Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo. Exp Hematol. 2002; 30:42-8.
15. Di Nicola M, Carlo-Stella C, Magni M, Milanesi M, Longoni PD, Matteucci P, et al. Human bone marrow stromal cells sup-press T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood. 2002; 99:3838-43.
16. Krampera M, Glennie S, Dyson J, Scott D, Laylor R, Simpson E, et al. Bone marrow mesenchymal stem cells inhibit the re-sponse of naive and memory antigen-specific T cells to their cognate peptide. Blood. 2003; 101:3722-9.
17. Jiang XX, Zhang Y, Liu B, Zhang SX, Wu Y, Yu XD, et al. Human mesenchymal stem cells inhibit differentiation and func-tion of monocyte-derived dendritic cells. Blood. 2005; 105:4120-6.
18. Corcione A, Benvenuto F, Ferretti E, Giunti D, Cappiello V, Cazzanti F, et al. Human mesenchymal stem cells modulate B-cell functions. Blood. 2006; 107:367-72.
19. Rasmusson I, Ringden O, Sundberg B, Le Blanc K. Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells. Transplantation. 2003; 76:1203-13.
20. Aggarwal S, Pittenger MF. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood. 2005; 105:1815-22.
21. Patel SA, Sherman L, Munoz J, Rameshwar P. Immunological properties of mesenchymal stem cells and clinical implications. Arch Immunol Ther Exp. 2008; 56:1-8.
22. Djouad F, Plence P, Bony C, Tropel P, Apparailly F, Sany J, et al. Immunosuppressive effect of mesenchymal stem cells fa-vors tumor growth in allogeneic animals. Blood. 2003; 102:3837-44.
23. Meisel R, Zibert A, Laryea M, Gobel U, Daubener W, Dilloo D. Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation. Blood. 2004; 103:4619-21.
24. Gur-Wahnon D, Borovsky Z, Beyth S, Liebergall M, Rachmilewitz J. Contact-dependent induction of regulatory antigen-presenting cells by human mesenchymal stem cells is mediated via STAT3 signaling. Exp Hematol. 2007; 35:426-33.
25. Beyth S, Borovsky Z, Mevorach D, Liebergall M, Gazit Z, Aslan H, et al. Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness. Blood. 2005; 105:2214-9.
26. Hall B, Andreef M, Marini F. The participation of mesenchymal stem cells in tumor stroma formation and their application as targeted-gene delivery vehicles. Handb. Exp Pharmacol. 2007; 180:263-83.
27. Parekkadan B, van Poll D, Megeed Z, Kobayashi N, Tilles AW, Berthiaume F, et al. Immunomodulation of activated hepatic stellate cells by mesenchymal stem cells. Biochem Biophys Res Commun. 2007; 363:247-52.
28. Schneider U, Schwenk HU, Bornkamm G. Characterization of EBV-genome negative null and T cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non-Hodgkin lymphoma. Int J Cancer. 1977; 19:621-6.
29. Gotherstrom C. Immunomodulation by multipotent mesenchymal stromal cells. Transplantation. 2007; 84:535-7.
30. Benvenuto F, Ferrari S, Gerdoni E, Gualandi F, Frassoni F, Pistoia V, et al. Human mesenchymal stem cells promote survival of T cells in a quiescent state. Stem Cells. 2007; 5:1753-60.
31. Ren G, Su J, Zhang L, Zhao X, Ling W, L'huillie A, et al. Species Variation in the Mechanisms of Mesenchymal Stem Cell-Mediated Immunosuppression. Stem Cells. 2009; 27:1954-62.