Gef gene therapy enhances the therapeutic efficacy of doxorubicin to combat growth of MCF-7 breast cancer cells

Cancer Chemotherapy and Pharmacology

Volumn 66, Issue 1, 2010, Pages 69-78

  Prados, Jose ^a   Melguizo, Consolación ^a   Rama, Ana Rosa ^a   Ortiz, Rául ^a   Segura, Ana ^c   Boulaiz, Houria ^a   Vélez, Celia ^a   Caba, Octavio ^b   Ramos, Juan Lúis ^c   Aránega, Antonia ^a  

^a UNIVERSITY OF GRANADA   (Spain)

^b UNIVERSITY OF JAÉN   (Spain)

^c CSIC   (Spain)

Author keywords

Breast cancer; Cytotoxic therapy; Doxorubicin; Gef gene; Gene therapy; Multicellular tumour spheroid

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; DOCETAXEL; DOXORUBICIN; GEF PROTEIN; GENE THERAPY AGENT; GREEN FLUORESCENT PROTEIN; PACLITAXEL; PLASMID DNA; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; BACTERIAL TOXIN; ESCHERICHIA COLI PROTEIN; HOKC PROTEIN, E COLI; MEMBRANE PROTEIN; TAXOID;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER COMBINATION CHEMOTHERAPY; CANCER GENE THERAPY; CANCER INHIBITION; CANCER MORPHOLOGY; CELL PROLIFERATION; CELL STRAIN MCF 7; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA FRAGMENTATION; DNA VECTOR; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG EFFICACY; DRUG INTERACTION; DRUG MECHANISM; DRUG POTENTIATION; EXPRESSION VECTOR; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STRUCTURE ANALYSIS; TUMOR SPHEROID; TUMOR VOLUME; BREAST TUMOR; CELL SURVIVAL; DRUG SCREENING; EVALUATION; FEMALE; GENE THERAPY; GENE VECTOR; GENETICS; METABOLISM; METHODOLOGY; MULTICELLULAR SPHEROID; MULTIMODALITY CANCER THERAPY; SUICIDE TRANSGENE; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BACTERIAL TOXINS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; COMBINED MODALITY THERAPY; DOXORUBICIN; DRUG SCREENING ASSAYS, ANTITUMOR; ESCHERICHIA COLI PROTEINS; FEMALE; GENE THERAPY; GENES, TRANSGENIC, SUICIDE; GENETIC VECTORS; HUMANS; MEMBRANE PROTEINS; PACLITAXEL; SPHEROIDS, CELLULAR; TAXOIDS; TRANSFECTION;

EID: 77951909801     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-009-1135-1     Document Type: Article

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