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Volumn 208, Issue 1, 2010, Pages 258-264

The modified Geller-Seifter test in rats was insensitive to GABA B receptor positive modulation or blockade, or 5-HT 1A receptor activation

Author keywords

8 OH DPAT; Alprazolam; CGP46381; GABA B receptor positive modulator; Geller Seifter; GS39783; MPEP; Predictive validity

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 4 AMINOBUTYRIC ACID B RECEPTOR; ALPRAZOLAM; ANXIOLYTIC AGENT; CGP 46381; CHLORDIAZEPOXIDE; DIAZEPAM; HALOPERIDOL; N,N' DICYCLOPENTYL 2 METHYLTHIO 5 NITRO 4,6 PYRIMIDINEDIAMINE; SEROTONIN 1A RECEPTOR; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID A RECEPTOR; 6 METHYL 2 (PHENYLETHYNYL)PYRIDINE; 6-METHYL-2-(PHENYLETHYNYL)PYRIDINE; AMINO ACID RECEPTOR BLOCKING AGENT; DOPAMINE RECEPTOR BLOCKING AGENT; GABAERGIC RECEPTOR AFFECTING AGENT; PYRIDINE DERIVATIVE; SEROTONIN AGONIST;

EID: 77951894045     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2009.12.006     Document Type: Article
Times cited : (16)

References (41)
  • 1
  • 2
    • 17744373871 scopus 로고    scopus 로고
    • The effect of the mGlu5 receptor antagonist MPEP in rodent tests of anxiety and cognition: a comparison
    • Ballard T.M., Woolley M.L., Prinssen E., Huwyler J., Porter R., Spooren W. The effect of the mGlu5 receptor antagonist MPEP in rodent tests of anxiety and cognition: a comparison. Psychopharmacology 2005, 179(1):218-229.
    • (2005) Psychopharmacology , vol.179 , Issue.1 , pp. 218-229
    • Ballard, T.M.1    Woolley, M.L.2    Prinssen, E.3    Huwyler, J.4    Porter, R.5    Spooren, W.6
  • 3
    • 3042685523 scopus 로고    scopus 로고
    • The behavioral profile of the potent and selective mGlu5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP) in rodent models of anxiety
    • Busse C.S., Brodkin J., Tattersall D., Anderson J.J., Warren N., Tehrani L., et al. The behavioral profile of the potent and selective mGlu5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP) in rodent models of anxiety. Neuropsychopharmacology 2004, 29(11):1971-1979.
    • (2004) Neuropsychopharmacology , vol.29 , Issue.11 , pp. 1971-1979
    • Busse, C.S.1    Brodkin, J.2    Tattersall, D.3    Anderson, J.J.4    Warren, N.5    Tehrani, L.6
  • 5
    • 0030741653 scopus 로고    scopus 로고
    • On the elevated plus-maze the anxiolytic-like effects of the 5-HT(1A) agonist, 8-OH-DPAT, but not the anxiogenic-like effects of the 5-HT(1A) partial agonist, buspirone, are blocked by the 5-HT1A antagonist, WAY 100635
    • Collinson N., Dawson G.R. On the elevated plus-maze the anxiolytic-like effects of the 5-HT(1A) agonist, 8-OH-DPAT, but not the anxiogenic-like effects of the 5-HT(1A) partial agonist, buspirone, are blocked by the 5-HT1A antagonist, WAY 100635. Psychopharmacology 1997, 132(1):35-43.
    • (1997) Psychopharmacology , vol.132 , Issue.1 , pp. 35-43
    • Collinson, N.1    Dawson, G.R.2
  • 6
    • 11144230982 scopus 로고    scopus 로고
    • Don't worry 'B' happy!: a role for GABA(B) receptors in anxiety and depression
    • Cryan J.F., Kaupmann K. Don't worry 'B' happy!: a role for GABA(B) receptors in anxiety and depression. Trends Pharmacol Sci 2005, 26(1):36-43.
    • (2005) Trends Pharmacol Sci , vol.26 , Issue.1 , pp. 36-43
    • Cryan, J.F.1    Kaupmann, K.2
  • 7
    • 4243086935 scopus 로고    scopus 로고
    • Behavioural characterization of the novel GABAB receptor positive modulator GS39783 (N,N0-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side-effects associated with baclofen or benzodiazepines
    • Cryan J.F., Kelly P.H., Chaperon F., Gentsch C., Mombereau C., Lingenhoehl K., et al. Behavioural characterization of the novel GABAB receptor positive modulator GS39783 (N,N0-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side-effects associated with baclofen or benzodiazepines. J Pharmacol Exp Ther 2004, 310:952-963.
    • (2004) J Pharmacol Exp Ther , vol.310 , pp. 952-963
    • Cryan, J.F.1    Kelly, P.H.2    Chaperon, F.3    Gentsch, C.4    Mombereau, C.5    Lingenhoehl, K.6
  • 8
    • 67649433595 scopus 로고    scopus 로고
    • First-line pharmacotherapy approaches for generalized anxiety disorder
    • Davidson J.R. First-line pharmacotherapy approaches for generalized anxiety disorder. J Clin Psychiatry 2009, 70(Suppl. 2):25-31.
    • (2009) J Clin Psychiatry , vol.70 , Issue.SUPPL. 2 , pp. 25-31
    • Davidson, J.R.1
  • 9
    • 0001671035 scopus 로고
    • The effects of chlordiazepoxide and chlorpromazine on a punishment discrimination
    • Geller I., Kulak J.T., Seifter J. The effects of chlordiazepoxide and chlorpromazine on a punishment discrimination. Psychopharmacologia 1962, 3:374-385.
    • (1962) Psychopharmacologia , vol.3 , pp. 374-385
    • Geller, I.1    Kulak, J.T.2    Seifter, J.3
  • 10
    • 33749513198 scopus 로고    scopus 로고
    • The pharmacology of the neurochemical transmission in the midbrain raphe nuclei of the rat
    • Harsing L.R. The pharmacology of the neurochemical transmission in the midbrain raphe nuclei of the rat. Curr Neuropharmacol 2006, 4:313-339.
    • (2006) Curr Neuropharmacol , vol.4 , pp. 313-339
    • Harsing, L.R.1
  • 11
    • 40849083238 scopus 로고    scopus 로고
    • Evaluation of the anxiolytic-like profile of the GABAB receptor positive modulator CGP7930 in rodents
    • Jacobson L.H., Cryan J.F. Evaluation of the anxiolytic-like profile of the GABAB receptor positive modulator CGP7930 in rodents. Neuropharmacology 2008, 54(5):854-862.
    • (2008) Neuropharmacology , vol.54 , Issue.5 , pp. 854-862
    • Jacobson, L.H.1    Cryan, J.F.2
  • 13
    • 0019411320 scopus 로고
    • Comparison of anti-conflict drug effects in three experimental animal models of anxiety
    • Kilts C.D., Commissaris R.L., Rech R.H. Comparison of anti-conflict drug effects in three experimental animal models of anxiety. Psychopharmacology 1981, 74(3):290-296.
    • (1981) Psychopharmacology , vol.74 , Issue.3 , pp. 290-296
    • Kilts, C.D.1    Commissaris, R.L.2    Rech, R.H.3
  • 14
    • 0030611697 scopus 로고    scopus 로고
    • Effects of 5-HT1A receptor ligands in a modified Geller-Seifter conflict model in the rat
    • King C.M., Gommans J., Joordens R.J., Hijzen T.H., Maes R.A., Olivier B. Effects of 5-HT1A receptor ligands in a modified Geller-Seifter conflict model in the rat. Eur J Pharmacol 1997, 325(2-3):121-128.
    • (1997) Eur J Pharmacol , vol.325 , Issue.2-3 , pp. 121-128
    • King, C.M.1    Gommans, J.2    Joordens, R.J.3    Hijzen, T.H.4    Maes, R.A.5    Olivier, B.6
  • 15
    • 0030950129 scopus 로고    scopus 로고
    • Assessment of the anxiolytic and amnesic effects of three benzodiazepines, diazepam, alprazolam and triazolam, by conflict and non-matching to sample tests in mice
    • Kuribara H., Asahi T. Assessment of the anxiolytic and amnesic effects of three benzodiazepines, diazepam, alprazolam and triazolam, by conflict and non-matching to sample tests in mice. Nihon Shinkei Seishin Yakurigaku Zasshi 1997, 17(1):1-6.
    • (1997) Nihon Shinkei Seishin Yakurigaku Zasshi , vol.17 , Issue.1 , pp. 1-6
    • Kuribara, H.1    Asahi, T.2
  • 16
    • 0035052473 scopus 로고    scopus 로고
    • Both GABA(B) receptor agonist and antagonists decreased brain stimulation reward in the rat
    • Macey D.J., Froestl W., Koob G.F., Markou A. Both GABA(B) receptor agonist and antagonists decreased brain stimulation reward in the rat. Neuropharmacology 2001, 40(5):676-685.
    • (2001) Neuropharmacology , vol.40 , Issue.5 , pp. 676-685
    • Macey, D.J.1    Froestl, W.2    Koob, G.F.3    Markou, A.4
  • 17
    • 2542443708 scopus 로고    scopus 로고
    • GABA(B) receptors in 5-HT transporter- and 5-HT1A receptor-knock-out mice: further evidence of a transduction pathway shared with 5-HT1A receptors
    • Mannoury la Cour C., Hanoun N., Melfort M., Hen R., Lesch K.P., Hamon M., et al. GABA(B) receptors in 5-HT transporter- and 5-HT1A receptor-knock-out mice: further evidence of a transduction pathway shared with 5-HT1A receptors. J Neurochem 2004, 89(4):886-896.
    • (2004) J Neurochem , vol.89 , Issue.4 , pp. 886-896
    • Mannoury la Cour, C.1    Hanoun, N.2    Melfort, M.3    Hen, R.4    Lesch, K.P.5    Hamon, M.6
  • 18
    • 0036119272 scopus 로고    scopus 로고
    • Influence of the 5-HT2C receptor antagonist, SB-242084, in tests of anxiety
    • Martin J.R., Ballard T.M., Higgins G.A. Influence of the 5-HT2C receptor antagonist, SB-242084, in tests of anxiety. Pharmacol Biochem Behav 2002, 71(4):615-625.
    • (2002) Pharmacol Biochem Behav , vol.71 , Issue.4 , pp. 615-625
    • Martin, J.R.1    Ballard, T.M.2    Higgins, G.A.3
  • 19
    • 2442682706 scopus 로고    scopus 로고
    • Genetic and pharmacological evidence of a role for GABA(B) receptors in the modulation of anxiety- and antidepressant-like behavior
    • Mombereau C., Kaupmann K., Froestl W., Sansig G., van der Putten H., Cryan J.F. Genetic and pharmacological evidence of a role for GABA(B) receptors in the modulation of anxiety- and antidepressant-like behavior. Neuropsychopharmacology 2004, 29(6):1050-1062.
    • (2004) Neuropsychopharmacology , vol.29 , Issue.6 , pp. 1050-1062
    • Mombereau, C.1    Kaupmann, K.2    Froestl, W.3    Sansig, G.4    van der Putten, H.5    Cryan, J.F.6
  • 20
    • 4143071653 scopus 로고    scopus 로고
    • Altered response to benzodiazepine anxiolytics in mice lacking GABA B(1) receptors
    • Mombereau C., Kaupmann K., van der Putten H., Cryan J.F. Altered response to benzodiazepine anxiolytics in mice lacking GABA B(1) receptors. Eur J Pharmacol 2004, 497(1):119-120.
    • (2004) Eur J Pharmacol , vol.497 , Issue.1 , pp. 119-120
    • Mombereau, C.1    Kaupmann, K.2    van der Putten, H.3    Cryan, J.F.4
  • 21
    • 33947355687 scopus 로고    scopus 로고
    • GABAB receptor-positive modulation-induced blockade of the rewarding properties of nicotine is associated with a reduction in nucleus accumbens DeltaFosB accumulation
    • Mombereau C., Lhuillier L., Kaupmann K., Cryan J.F. GABAB receptor-positive modulation-induced blockade of the rewarding properties of nicotine is associated with a reduction in nucleus accumbens DeltaFosB accumulation. J Pharmacol Exp Ther 2007, 321(1):172-177.
    • (2007) J Pharmacol Exp Ther , vol.321 , Issue.1 , pp. 172-177
    • Mombereau, C.1    Lhuillier, L.2    Kaupmann, K.3    Cryan, J.F.4
  • 22
    • 0026757929 scopus 로고
    • The behavioral pharmacology of olanzapine, a novel " atypical" antipsychotic agent
    • Moore N.A., Tye N.C., Axton M.S., Risius F.C. The behavioral pharmacology of olanzapine, a novel " atypical" antipsychotic agent. J Pharmacol Exp Ther 1992, 262(2):545-551.
    • (1992) J Pharmacol Exp Ther , vol.262 , Issue.2 , pp. 545-551
    • Moore, N.A.1    Tye, N.C.2    Axton, M.S.3    Risius, F.C.4
  • 23
    • 0025248204 scopus 로고
    • Characterization of MDL 73005EF as a 5-HT1A selective ligand and its effects in animal models of anxiety: comparison with buspirone, 8-OH-DPAT and diazepam
    • Moser P.C., Tricklebank M.D., Middlemiss D.N., Mir A.K., Hibert M.F., Fozard J.R. Characterization of MDL 73005EF as a 5-HT1A selective ligand and its effects in animal models of anxiety: comparison with buspirone, 8-OH-DPAT and diazepam. Br J Pharmacol 1990, 99(2):343-349.
    • (1990) Br J Pharmacol , vol.99 , Issue.2 , pp. 343-349
    • Moser, P.C.1    Tricklebank, M.D.2    Middlemiss, D.N.3    Mir, A.K.4    Hibert, M.F.5    Fozard, J.R.6
  • 24
    • 0003633755 scopus 로고    scopus 로고
    • National Academy Press, Washington, DC ,National Institutes of Health
    • National Institutes of Health Guide for the care and use of laboratory animals 1996, National Academy Press, Washington, DC.
    • (1996) Guide for the care and use of laboratory animals
  • 25
    • 0027419659 scopus 로고
    • The actions of orally active GABAB receptor antagonists on GABAergic transmission in vivo and in vitro
    • Olpe H.R., Steinmann M.W., Ferrat T., Pozza M.F., Greiner K., Brugger F., et al. The actions of orally active GABAB receptor antagonists on GABAergic transmission in vivo and in vitro. Eur J Pharmacol 1993, 233(2-3):179-186.
    • (1993) Eur J Pharmacol , vol.233 , Issue.2-3 , pp. 179-186
    • Olpe, H.R.1    Steinmann, M.W.2    Ferrat, T.3    Pozza, M.F.4    Greiner, K.5    Brugger, F.6
  • 27
    • 1642328942 scopus 로고    scopus 로고
    • The GABAB receptor agonists baclofen and CGP44532 decreased nicotine self-administration in the rat
    • Paterson N.E., Froestl W., Markou A. The GABAB receptor agonists baclofen and CGP44532 decreased nicotine self-administration in the rat. Psychopharmacology 2004, 172(2):179-186.
    • (2004) Psychopharmacology , vol.172 , Issue.2 , pp. 179-186
    • Paterson, N.E.1    Froestl, W.2    Markou, A.3
  • 28
    • 45749130575 scopus 로고    scopus 로고
    • Positive modulation of GABA(B) receptors decreased nicotine self-administration and counteracted nicotine-induced enhancement of brain reward function in rats
    • Paterson N.E., Vlachou S., Guery S., Kaupmann K., Froestl W., Markou A. Positive modulation of GABA(B) receptors decreased nicotine self-administration and counteracted nicotine-induced enhancement of brain reward function in rats. J Pharmacol Exp Ther 2008, 326(1):306-314.
    • (2008) J Pharmacol Exp Ther , vol.326 , Issue.1 , pp. 306-314
    • Paterson, N.E.1    Vlachou, S.2    Guery, S.3    Kaupmann, K.4    Froestl, W.5    Markou, A.6
  • 29
    • 27144537834 scopus 로고    scopus 로고
    • Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity
    • Porter R.H., Jaeschke G., Spooren W., Ballard T.M., Büttelmann B., Kolczewski S., et al. Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity. J Pharmacol Exp Ther 2005, 315(2):711-721.
    • (2005) J Pharmacol Exp Ther , vol.315 , Issue.2 , pp. 711-721
    • Porter, R.H.1    Jaeschke, G.2    Spooren, W.3    Ballard, T.M.4    Büttelmann, B.5    Kolczewski, S.6
  • 30
    • 0026773458 scopus 로고
    • Increased rates of punished responding produced by buspirone-like compounds in rats
    • Sanger D.J. Increased rates of punished responding produced by buspirone-like compounds in rats. J Pharmacol Exp Ther 1992, 261(2):513-517.
    • (1992) J Pharmacol Exp Ther , vol.261 , Issue.2 , pp. 513-517
    • Sanger, D.J.1
  • 31
    • 0027424061 scopus 로고
    • Neuronal circuits involved in the anxiolytic effects of the 5-HT1A receptor agonists 8-OH-DPAT ipsapirone and buspirone in the rat
    • Schreiber R., De Vry J. Neuronal circuits involved in the anxiolytic effects of the 5-HT1A receptor agonists 8-OH-DPAT ipsapirone and buspirone in the rat. Eur J Pharmacol 1993, 249(3):341-351.
    • (1993) Eur J Pharmacol , vol.249 , Issue.3 , pp. 341-351
    • Schreiber, R.1    De Vry, J.2
  • 32
    • 0026539430 scopus 로고
    • Direct evidence for mediation of an anticonflict effect of baclofen by GABAb receptors
    • Shephard R.A., Wedlock P., Wilson N.E. Direct evidence for mediation of an anticonflict effect of baclofen by GABAb receptors. Pharmacol Biochem Behav 1992, 41:651-653.
    • (1992) Pharmacol Biochem Behav , vol.41 , pp. 651-653
    • Shephard, R.A.1    Wedlock, P.2    Wilson, N.E.3
  • 33
    • 0026562843 scopus 로고
    • Anticonflict action of tandospirone in a modified Geller-Seifter conflict test in rats
    • Shimizu H., Kumasaka Y., Tanaka H., Hirose A., Nakamura M. Anticonflict action of tandospirone in a modified Geller-Seifter conflict test in rats. Jpn J Pharmacol 1992, 58(3):283-289.
    • (1992) Jpn J Pharmacol , vol.58 , Issue.3 , pp. 283-289
    • Shimizu, H.1    Kumasaka, Y.2    Tanaka, H.3    Hirose, A.4    Nakamura, M.5
  • 34
    • 11844251298 scopus 로고    scopus 로고
    • GABAB receptor antagonist-mediated antidepressant-like behavior is serotonin-dependent
    • Slattery D.A., Desrayaud S., Cryan J.F. GABAB receptor antagonist-mediated antidepressant-like behavior is serotonin-dependent. J Pharmacol Exp Ther 2005, 312(1):290-296.
    • (2005) J Pharmacol Exp Ther , vol.312 , Issue.1 , pp. 290-296
    • Slattery, D.A.1    Desrayaud, S.2    Cryan, J.F.3
  • 35
    • 27144453948 scopus 로고    scopus 로고
    • The GABAB receptor-positive modulator GS39783 and the GABAB receptor agonist baclofen attenuate the reward-facilitating effects of cocaine: intracranial self-stimulation studies in the rat
    • Slattery D.A., Markou A., Froestl W., Cryan J.F. The GABAB receptor-positive modulator GS39783 and the GABAB receptor agonist baclofen attenuate the reward-facilitating effects of cocaine: intracranial self-stimulation studies in the rat. Neuropsychopharmacology 2005, 30(11):2065-2072.
    • (2005) Neuropsychopharmacology , vol.30 , Issue.11 , pp. 2065-2072
    • Slattery, D.A.1    Markou, A.2    Froestl, W.3    Cryan, J.F.4
  • 36
    • 2342588048 scopus 로고    scopus 로고
    • Effects of positive allosteric modulators of the GABAB receptor on cocaine self-administration in rats
    • Smith M.A., Yancey D.L., Morgan D., Liu Y., Froestl W., Roberts D.C. Effects of positive allosteric modulators of the GABAB receptor on cocaine self-administration in rats. Psychopharmacology 2004, 173(1-2):105-111.
    • (2004) Psychopharmacology , vol.173 , Issue.1-2 , pp. 105-111
    • Smith, M.A.1    Yancey, D.L.2    Morgan, D.3    Liu, Y.4    Froestl, W.5    Roberts, D.C.6
  • 37
    • 0034760504 scopus 로고    scopus 로고
    • Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501
    • Urwyler S., Mosbacher J., Lingenhoehl K., Heid J., Hofstetter K., Froestl W., et al. Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Mol Pharmacol 2001, 60(5):963-971.
    • (2001) Mol Pharmacol , vol.60 , Issue.5 , pp. 963-971
    • Urwyler, S.1    Mosbacher, J.2    Lingenhoehl, K.3    Heid, J.4    Hofstetter, K.5    Froestl, W.6
  • 38
    • 0141742370 scopus 로고    scopus 로고
    • N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) and structurally related compounds: novel allosteric enhancers of gamma-aminobutyric acid B receptor function
    • Urwyler S., Pozza M.F., Lingenhoehl K., Mosbacher J., Lampert C., Froestl W., et al. N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) and structurally related compounds: novel allosteric enhancers of gamma-aminobutyric acid B receptor function. J Pharmacol Exp Ther 2003, 307(1):322-330.
    • (2003) J Pharmacol Exp Ther , vol.307 , Issue.1 , pp. 322-330
    • Urwyler, S.1    Pozza, M.F.2    Lingenhoehl, K.3    Mosbacher, J.4    Lampert, C.5    Froestl, W.6
  • 39
    • 0019229764 scopus 로고
    • Attenuation of the effects of punishment by ethanol: comparisons with chlordiazepoxide
    • Vogel R.A., Frye G.D., Wilson J.H., Kuhn C.M., Koepke K.M., Mailman R.B., et al. Attenuation of the effects of punishment by ethanol: comparisons with chlordiazepoxide. Psychopharmacology 1980, 71(2):123-129.
    • (1980) Psychopharmacology , vol.71 , Issue.2 , pp. 123-129
    • Vogel, R.A.1    Frye, G.D.2    Wilson, J.H.3    Kuhn, C.M.4    Koepke, K.M.5    Mailman, R.B.6
  • 40
    • 0027189962 scopus 로고
    • Effects of four antipsychotics on punished responding in rats
    • Wiley J.L., Compton A.D., Porter J.H. Effects of four antipsychotics on punished responding in rats. Pharmacol Biochem Behav 1993, 45(2):263-267.
    • (1993) Pharmacol Biochem Behav , vol.45 , Issue.2 , pp. 263-267
    • Wiley, J.L.1    Compton, A.D.2    Porter, J.H.3
  • 41
    • 0034903523 scopus 로고    scopus 로고
    • SB-243213; a selective 5-HT2C receptor inverse agonist with improved anxiolytic profile: lack of tolerance and withdrawal anxiety
    • Wood M.D., Reavill C., Trail B., Wilson A., Stean T., Kennett G.A., et al. SB-243213; a selective 5-HT2C receptor inverse agonist with improved anxiolytic profile: lack of tolerance and withdrawal anxiety. Neuropharmacology 2001, 41(2):186-199.
    • (2001) Neuropharmacology , vol.41 , Issue.2 , pp. 186-199
    • Wood, M.D.1    Reavill, C.2    Trail, B.3    Wilson, A.4    Stean, T.5    Kennett, G.A.6


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