메뉴 건너뛰기




Volumn 184, Issue 6, 2010, Pages 2776-2784

ADP-ribosylation controls the outcome of tolerance or enhanced priming following mucosal immunization

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; CHOLERA TOXIN; IMMUNOGLOBULIN A; INTERLEUKIN 10; TRANSCRIPTION FACTOR FOXP3; HYBRID PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; OVA 323 339; OVA 323-339; OVALBUMIN; PEPTIDE FRAGMENT;

EID: 77951887579     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0901445     Document Type: Article
Times cited : (9)

References (60)
  • 2
    • 0038316325 scopus 로고    scopus 로고
    • Anatomical basis of tolerance and immunity to intestinal antigens
    • Mowat, A. M. 2003. Anatomical basis of tolerance and immunity to intestinal antigens. Nat. Rev. Immunol. 3: 331-341.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 331-341
    • Mowat, A.M.1
  • 3
    • 0035426510 scopus 로고    scopus 로고
    • Immunomodulators and delivery systems for vaccination by mucosal routes
    • Ryan, E. J., L. M. Daly, and K. H. Mills. 2001. Immunomodulators and delivery systems for vaccination by mucosal routes. Trends Biotechnol. 19: 293-304.
    • (2001) Trends Biotechnol. , vol.19 , pp. 293-304
    • Ryan, E.J.1    Daly, L.M.2    Mills, K.H.3
  • 4
    • 33644836224 scopus 로고    scopus 로고
    • Mucosal vaccines: The promise and the challenge
    • Neutra, M. R., and P. A. Kozlowski. 2006. Mucosal vaccines: the promise and the challenge. Nat. Rev. Immunol. 6: 148-158.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 148-158
    • Neutra, M.R.1    Kozlowski, P.A.2
  • 5
    • 60849124499 scopus 로고    scopus 로고
    • Allergen-related approaches to immunotherapy
    • Rolland, J. M., L. M. Gardner, and R. E. O'Hehir. 2009. Allergen-related approaches to immunotherapy. Pharmacol. Ther. 121: 273-284.
    • (2009) Pharmacol. Ther. , vol.121 , pp. 273-284
    • Rolland, J.M.1    Gardner, L.M.2    O'Hehir, R.E.3
  • 6
    • 38449107450 scopus 로고    scopus 로고
    • Perspectives on mucosal vaccines: Is mucosal tolerance a barrier?
    • Mestecky, J., M. W. Russell, and C. O. Elson. 2007. Perspectives on mucosal vaccines: is mucosal tolerance a barrier? J. Immunol. 179: 5633-5638.
    • (2007) J. Immunol. , vol.179 , pp. 5633-5638
    • Mestecky, J.1    Russell, M.W.2    Elson, C.O.3
  • 7
    • 35348854507 scopus 로고    scopus 로고
    • Sublingual allergen immunotherapy: Immunological mechanisms and prospects for refined vaccine preparation
    • O'Hehir, R. E., A. Sandrini, G. P. Anderson, and J. M. Rolland. 2007. Sublingual allergen immunotherapy: immunological mechanisms and prospects for refined vaccine preparation. Curr. Med. Chem. 14: 2235-2244.
    • (2007) Curr. Med. Chem. , vol.14 , pp. 2235-2244
    • O'Hehir, R.E.1    Sandrini, A.2    Anderson, G.P.3    Rolland, J.M.4
  • 8
    • 6944244007 scopus 로고    scopus 로고
    • Regulation of antigen-specific regulatory T-cell induction via nasal and oral mucosa
    • Samsom, J. N. 2004. Regulation of antigen-specific regulatory T-cell induction via nasal and oral mucosa. Crit. Rev. Immunol. 24: 157-177.
    • (2004) Crit. Rev. Immunol. , vol.24 , pp. 157-177
    • Samsom, J.N.1
  • 9
    • 33845662118 scopus 로고    scopus 로고
    • Oral tolerance: Therapeutic implications for autoimmune diseases
    • Faria, A. M., and H. L.Weiner. 2006. Oral tolerance: therapeutic implications for autoimmune diseases. Clin. Dev. Immunol. 13: 143-157.
    • (2006) Clin. Dev. Immunol. , vol.13 , pp. 143-157
    • Faria, A.M.1    Weiner, H.L.2
  • 10
    • 48849107455 scopus 로고    scopus 로고
    • Vitamin A rewrites the ABCs of oral tolerance
    • Strober, W. 2008. Vitamin A rewrites the ABCs of oral tolerance. Mucosal Immunol. 1: 92-95.
    • (2008) Mucosal Immunol. , vol.1 , pp. 92-95
    • Strober, W.1
  • 11
    • 33750808166 scopus 로고    scopus 로고
    • Induction of tolerance to innocuous inhaled antigen relies on a CCR7-dependent dendritic cell-mediated antigen transport to the bronchial lymph node
    • Hintzen, G., L. Ohl, M. L. del Rio, J. I. Rodriguez-Barbosa, O. Pabst, J. R. Kocks, J. Krege, S. Hardtke, and R. Förster. 2006. Induction of tolerance to innocuous inhaled antigen relies on a CCR7-dependent dendritic cell-mediated antigen transport to the bronchial lymph node. J. Immunol. 177: 7346-7354. (Pubitemid 44715105)
    • (2006) Journal of Immunology , vol.177 , Issue.10 , pp. 7346-7354
    • Hintzen, G.1    Ohl, L.2    Del Rio, M.-L.3    Rodriguez-Barbosa, J.-I.4    Pabst, O.5    Kocks, J.R.6    Krege, J.7    Hardtke, S.8    Forster, R.9
  • 12
  • 13
    • 59349086101 scopus 로고    scopus 로고
    • Mechanisms of adjuvant action
    • M. Singh, ed. Wiley, Hoboken, New Jersey
    • Lycke, N. 2007. Mechanisms of adjuvant action. In Vaccine Adjuvants and Delivery Systems. M. Singh, ed. Wiley, Hoboken, New Jersey.
    • (2007) Vaccine Adjuvants and Delivery Systems
    • Lycke, N.1
  • 14
    • 0033929615 scopus 로고    scopus 로고
    • Enterotoxin adjuvants have direct effects on T cells and antigen-presenting cells that result in either interleukin-4-dependent or -independent immune responses
    • Yamamoto, M., H. Kiyono, M. N. Kweon, S. Yamamoto, K. Fujihashi, H. Kurazono, K. Imaoka, H. Bluethmann, I. Takahashi, Y. Takeda, et al. 2000. Enterotoxin adjuvants have direct effects on T cells and antigen-presenting cells that result in either interleukin-4-dependent or -independent immune responses. J. Infect. Dis. 182: 180-190.
    • (2000) J. Infect. Dis. , vol.182 , pp. 180-190
    • Yamamoto, M.1    Kiyono, H.2    Kweon, M.N.3    Yamamoto, S.4    Fujihashi, K.5    Kurazono, H.6    Imaoka, K.7    Bluethmann, H.8    Takahashi, I.9    Takeda, Y.10
  • 15
    • 50849121427 scopus 로고    scopus 로고
    • Cholera toxin B subunit promotes the induction of regulatory T cells by preventing human dendritic cell maturation
    • D'Ambrosio, A., M. Colucci, O. Pugliese, F. Quintieri, and M. Boirivant. 2008. Cholera toxin B subunit promotes the induction of regulatory T cells by preventing human dendritic cell maturation. J. Leukoc. Biol. 84: 661-668.
    • (2008) J. Leukoc. Biol. , vol.84 , pp. 661-668
    • D'Ambrosio, A.1    Colucci, M.2    Pugliese, O.3    Quintieri, F.4    Boirivant, M.5
  • 16
    • 17644371966 scopus 로고    scopus 로고
    • Mucosal immunity and vaccines
    • Holmgren, J., and C. Czerkinsky. 2005. Mucosal immunity and vaccines. Nat. Med. 11(4): Suppl): S45-S53.
    • (2005) Nat. Med. , vol.11 , Issue.4 SUPPL.
    • Holmgren, J.1    Czerkinsky, C.2
  • 17
    • 0033083188 scopus 로고    scopus 로고
    • Immune modulation by the cholera-like enterotoxins: From adjuvant to therapeutic
    • Williams, N. A., T. R. Hirst, and T. O. Nashar. 1999. Immune modulation by the cholera-like enterotoxins: from adjuvant to therapeutic. Immunol. Today 20: 95-101.
    • (1999) Immunol. Today , vol.20 , pp. 95-101
    • Williams, N.A.1    Hirst, T.R.2    Nashar, T.O.3
  • 18
    • 0032489830 scopus 로고    scopus 로고
    • Mucosal adjuvanticity and immunogenicity of LTR72, a novel mutant of Escherichia coli heat-labile enterotoxin with partial knockout of ADP-ribosyltransferase activity
    • Giuliani, M. M., G. Del Giudice, V. Giannelli, G. Dougan, G. Douce, R. Rappuoli, and M. Pizza. 1998. Mucosal adjuvanticity and immunogenicity of LTR72, a novel mutant of Escherichia coli heat-labile enterotoxin with partial knockout of ADP-ribosyltransferase activity. J. Exp. Med. 187: 1123-1132.
    • (1998) J. Exp. Med. , vol.187 , pp. 1123-1132
    • Giuliani, M.M.1    Del Giudice, G.2    Giannelli, V.3    Dougan, G.4    Douce, G.5    Rappuoli, R.6    Pizza, M.7
  • 20
    • 0031569528 scopus 로고    scopus 로고
    • Genetically engineered nontoxic vaccine adjuvant that combines B cell targeting with immunomodulation by cholera toxin A1 subunit
    • Agren, L. C., L. Ekman, B. Löwenadler, and N. Y. Lycke. 1997. Genetically engineered nontoxic vaccine adjuvant that combines B cell targeting with immunomodulation by cholera toxin A1 subunit. J. Immunol. 158: 3936-3946.
    • (1997) J. Immunol. , vol.158 , pp. 3936-3946
    • Agren, L.C.1    Ekman, L.2    Löwenadler, B.3    Lycke, N.Y.4
  • 21
    • 0033557754 scopus 로고    scopus 로고
    • Adjuvanticity of the cholera toxin A1-based gene fusion protein, CTA1-DD, is critically dependent on the ADP-ribosyltransferase and Ig-binding activity
    • Agren, L. C., L. Ekman, B. Löwenadler, J. G. Nedrud, and N. Y. Lycke. 1999. Adjuvanticity of the cholera toxin A1-based gene fusion protein, CTA1-DD, is critically dependent on the ADP-ribosyltransferase and Ig-binding activity. J. Immunol. 162: 2432-2440.
    • (1999) J. Immunol. , vol.162 , pp. 2432-2440
    • Agren, L.C.1    Ekman, L.2    Löwenadler, B.3    Nedrud, J.G.4    Lycke, N.Y.5
  • 22
    • 33645065850 scopus 로고    scopus 로고
    • The nontoxic CTA1-DD adjuvant enhances protective immunity against Helicobacter pylori infection following mucosal immunization
    • Akhiani, A. A., A. Stensson, K. Schön, and N. Lycke. 2006. The nontoxic CTA1-DD adjuvant enhances protective immunity against Helicobacter pylori infection following mucosal immunization. Scand. J. Immunol. 63: 97-105.
    • (2006) Scand. J. Immunol. , vol.63 , pp. 97-105
    • Akhiani, A.A.1    Stensson, A.2    Schön, K.3    Lycke, N.4
  • 24
    • 4344665014 scopus 로고    scopus 로고
    • The cholera toxin-derived CTA1-DD vaccine adjuvant administered intranasally does not cause inflammation or accumulate in the nervous tissues
    • Eriksson, A. M., K. M. Schön, and N. Y. Lycke. 2004. The cholera toxin-derived CTA1-DD vaccine adjuvant administered intranasally does not cause inflammation or accumulate in the nervous tissues. J. Immunol. 173: 3310-3319.
    • (2004) J. Immunol. , vol.173 , pp. 3310-3319
    • Eriksson, A.M.1    Schön, K.M.2    Lycke, N.Y.3
  • 25
    • 0034327167 scopus 로고    scopus 로고
    • Cutting edge: The mucosal adjuvant cholera toxin redirects vaccine proteins into olfactory tissues
    • van Ginkel, F. W., R. J. Jackson, Y. Yuki, and J. R. McGhee. 2000. Cutting edge: the mucosal adjuvant cholera toxin redirects vaccine proteins into olfactory tissues. J. Immunol. 165: 4778-4782.
    • (2000) J. Immunol. , vol.165 , pp. 4778-4782
    • Van Ginkel, F.W.1    Jackson, R.J.2    Yuki, Y.3    McGhee, J.R.4
  • 26
    • 0028359368 scopus 로고
    • Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor
    • Kirberg, J., A. Baron, S. Jakob, A. Rolink, K. Karjalainen, and H. von Boehmer. 1994. Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor. J. Exp. Med. 180: 25-34.
    • (1994) J. Exp. Med. , vol.180 , pp. 25-34
    • Kirberg, J.1    Baron, A.2    Jakob, S.3    Rolink, A.4    Karjalainen, K.5    Von Boehmer, H.6
  • 27
    • 0027521572 scopus 로고
    • Interleukin-10-deficient mice develop chronic enterocolitis
    • DOI 10.1016/0092-8674(93)80068-P
    • Kühn, R., J. Löhler, D. Rennick, K. Rajewsky, and W. Müller. 1993. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75: 263-274. (Pubitemid 23320290)
    • (1993) Cell , vol.75 , Issue.2 , pp. 263-274
    • Kuhn, R.1    Lohler, J.2    Rennick, D.3    Rajewsky, K.4    Muller, W.5
  • 28
    • 0025697469 scopus 로고
    • Induction by antigen of intrathymic apoptosis ofCD4+CD8+TCRlo thymocytes in vivo
    • Murphy, K. M., A. B. Heimberger, and D. Y. Loh. 1990. Induction by antigen of intrathymic apoptosis ofCD4+CD8+TCRlo thymocytes in vivo. Science 250: 1720-1723.
    • (1990) Science , vol.250 , pp. 1720-1723
    • Murphy, K.M.1    Heimberger, A.B.2    Loh, D.Y.3
  • 29
    • 26844495178 scopus 로고    scopus 로고
    • Splenic marginal zone dendritic cells mediate the cholera toxin adjuvant effect: Dependence on the ADP-ribosyltransferase activity of the holotoxin
    • Grdic, D., L. Ekman, K. Schön, K. Lindgren, J. Mattsson, K. E. Magnusson, P. Ricciardi-Castagnoli, and N. Lycke. 2005. Splenic marginal zone dendritic cells mediate the cholera toxin adjuvant effect: dependence on the ADP-ribosyltransferase activity of the holotoxin. J. Immunol. 175: 5192-5202. (Pubitemid 41456404)
    • (2005) Journal of Immunology , vol.175 , Issue.8 , pp. 5192-5202
    • Grdic, D.1    Ekman, L.2    Schon, K.3    Lindgren, K.4    Mattsson, J.5    Magnusson, K.-E.6    Ricciardi-Castagnoli, P.7    Lycke, N.8
  • 35
    • 55149111143 scopus 로고    scopus 로고
    • Diversity in the contribution of interleukin-10 to T-cell-mediated immune regulation
    • Maynard, C. L., and C. T.Weaver. 2008. Diversity in the contribution of interleukin-10 to T-cell-mediated immune regulation. Immunol. Rev. 226: 219-233.
    • (2008) Immunol. Rev. , vol.226 , pp. 219-233
    • Maynard, C.L.1    Weaver, C.T.2
  • 36
    • 34548131112 scopus 로고    scopus 로고
    • Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3- precursor cells in the absence of interleukin 10
    • Maynard, C. L., L. E. Harrington, K. M. Janowski, J. R. Oliver, C. L. Zindl, A. Y. Rudensky, and C. T. Weaver. 2007. Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3- precursor cells in the absence of interleukin 10. Nat. Immunol. 8: 931-941.
    • (2007) Nat. Immunol. , vol.8 , pp. 931-941
    • Maynard, C.L.1    Harrington, L.E.2    Janowski, K.M.3    Oliver, J.R.4    Zindl, C.L.5    Rudensky, A.Y.6    Weaver, C.T.7
  • 37
    • 0030704726 scopus 로고    scopus 로고
    • + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
    • DOI 10.1038/39614
    • Groux, H., A. O'Garra, M. Bigler, M. Rouleau, S. Antonenko, J. E. de Vries, and M. G. Roncarolo. 1997. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 389: 737-742. (Pubitemid 27458961)
    • (1997) Nature , vol.389 , Issue.6652 , pp. 737-742
    • Groux, H.1    O'Garra, A.2    Bigler, M.3    Rouleau, M.4    Antonenko, S.5    De Vries, J.E.6    Roncarolo, M.G.7
  • 38
    • 1242290580 scopus 로고    scopus 로고
    • Natural and induced CD4+CD25+ cells educate CD4+CD25- Cells to develop suppressive activity: The role of IL-2, TGF-β, and IL-10
    • Zheng, S. G., J. H.Wang, J. D. Gray, H. Soucier, and D. A. Horwitz. 2004. Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-β, and IL-10. J. Immunol. 172: 5213-5221.
    • (2004) J. Immunol. , vol.172 , pp. 5213-5221
    • Zheng, S.G.1    Wang, J.H.2    Gray, J.D.3    Soucier, H.4    Horwitz, D.A.5
  • 39
    • 55149094739 scopus 로고    scopus 로고
    • Interleukin-10: New perspectives on an old cytokine
    • Mosser, D. M., and X. Zhang. 2008. Interleukin-10: new perspectives on an old cytokine. Immunol. Rev. 226: 205-218.
    • (2008) Immunol. Rev. , vol.226 , pp. 205-218
    • Mosser, D.M.1    Zhang, X.2
  • 40
    • 33745700364 scopus 로고    scopus 로고
    • Understanding and exploiting the endogenous interleukin-10/STAT3-mediated anti-inflammatory response
    • Murray, P. J. 2006. Understanding and exploiting the endogenous interleukin-10/STAT3-mediated anti-inflammatory response. Curr. Opin. Pharmacol. 6: 379-386.
    • (2006) Curr. Opin. Pharmacol. , vol.6 , pp. 379-386
    • Murray, P.J.1
  • 42
    • 34249678457 scopus 로고    scopus 로고
    • T(H)1 cells control themselves by producing interleukin-10
    • O'Garra, A., and P. Vieira. 2007. T(H)1 cells control themselves by producing interleukin-10. Nat. Rev. Immunol. 7: 425-428.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 425-428
    • O'Garra, A.1    Vieira, P.2
  • 43
    • 0026000892 scopus 로고
    • Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression
    • de Waal Malefyt, R., J. Haanen, H. Spits, M. G. Roncarolo, A. te Velde, C. Figdor, K. Johnson, R. Kastelein, H. Yssel, and J. E. de Vries. 1991. Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression. J. Exp. Med. 174: 915-924.
    • (1991) J. Exp. Med. , vol.174 , pp. 915-924
    • De Waal Malefyt, R.1    Haanen, J.2    Spits, H.3    Roncarolo, M.G.4    Te Velde, A.5    Figdor, C.6    Johnson, K.7    Kastelein, R.8    Yssel, H.9    De Vries, J.E.10
  • 45
    • 0027239842 scopus 로고
    • IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression
    • Ding, L., P. S. Linsley, L. Y. Huang, R. N. Germain, and E. M. Shevach. 1993. IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression. J. Immunol. 151: 1224-1234.
    • (1993) J. Immunol. , vol.151 , pp. 1224-1234
    • Ding, L.1    Linsley, P.S.2    Huang, L.Y.3    Germain, R.N.4    Shevach, E.M.5
  • 46
    • 0027281346 scopus 로고
    • Human interleukin-10 can directly inhibit T-cell growth
    • Taga, K., H. Mostowski, and G. Tosato. 1993. Human interleukin-10 can directly inhibit T-cell growth. Blood 81: 2964-2971.
    • (1993) Blood , vol.81 , pp. 2964-2971
    • Taga, K.1    Mostowski, H.2    Tosato, G.3
  • 47
    • 65449120436 scopus 로고    scopus 로고
    • IL-10 interferes directly with TCR-induced IFN-g but not IL-17 production in memory T cells
    • Naundorf, S., M. Schröder, C. Höflich, N. Suman, H. D. Volk, and G. Grütz. 2009. IL-10 interferes directly with TCR-induced IFN-g but not IL-17 production in memory T cells. Eur. J. Immunol. 39: 1066-1077.
    • (2009) Eur. J. Immunol. , vol.39 , pp. 1066-1077
    • Naundorf, S.1    Schröder, M.2    Höflich, C.3    Suman, N.4    Volk, H.D.5    Grütz, G.6
  • 48
    • 0033198184 scopus 로고    scopus 로고
    • Intranasal exposure to protein antigen induces immunological tolerance mediated by functionally disabled CD4+ T cells
    • Tsitoura, D. C., R. H. DeKruyff, J. R. Lamb, and D. T. Umetsu. 1999. Intranasal exposure to protein antigen induces immunological tolerance mediated by functionally disabled CD4+ T cells. J. Immunol. 163: 2592-2600.
    • (1999) J. Immunol. , vol.163 , pp. 2592-2600
    • Tsitoura, D.C.1    Dekruyff, R.H.2    Lamb, J.R.3    Umetsu, D.T.4
  • 50
    • 33747055056 scopus 로고    scopus 로고
    • Sublingual tolerance induction with antigen conjugated to cholera toxin B subunit induces Foxp3+CD25+CD4+ regulatory T cells and suppresses delayed-type hypersensitivity reactions
    • Sun, J. B., N. Cuburu, M. Blomquist, B. L. Li, C. Czerkinsky, and J. Holmgren. 2006. Sublingual tolerance induction with antigen conjugated to cholera toxin B subunit induces Foxp3+CD25+CD4+ regulatory T cells and suppresses delayed-type hypersensitivity reactions. Scand. J. Immunol. 64: 251-259.
    • (2006) Scand. J. Immunol. , vol.64 , pp. 251-259
    • Sun, J.B.1    Cuburu, N.2    Blomquist, M.3    Li, B.L.4    Czerkinsky, C.5    Holmgren, J.6
  • 51
    • 0030030530 scopus 로고    scopus 로고
    • Potent immunogenicity of the B subunits of Escherichia coli heat-labile enterotoxin: Receptor binding is essential and induces differential modulation of lymphocyte subsets
    • Nashar, T. O., H. M. Webb, S. Eaglestone, N. A. Williams, and T. R. Hirst. 1996. Potent immunogenicity of the B subunits of Escherichia coli heat-labile enterotoxin: receptor binding is essential and induces differential modulation of lymphocyte subsets. Proc. Natl. Acad. Sci. USA 93: 226-230.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 226-230
    • Nashar, T.O.1    Webb, H.M.2    Eaglestone, S.3    Williams, N.A.4    Hirst, T.R.5
  • 52
    • 33751567891 scopus 로고    scopus 로고
    • Oral tolerance induction with antigen conjugated to cholera toxin B subunit generates both Foxp3+CD25+ and Foxp3-CD25- CD4+ regulatory T cells
    • Sun, J. B., S. Raghavan, A. Sjöling, S. Lundin, and J. Holmgren. 2006. Oral tolerance induction with antigen conjugated to cholera toxin B subunit generates both Foxp3+CD25+ and Foxp3-CD25- CD4+ regulatory T cells. J. Immunol. 177: 7634-7644.
    • (2006) J. Immunol. , vol.177 , pp. 7634-7644
    • Sun, J.B.1    Raghavan, S.2    Sjöling, A.3    Lundin, S.4    Holmgren, J.5
  • 53
    • 58849161852 scopus 로고    scopus 로고
    • B lymphocytes promote expansion of regulatory T cells in oral tolerance: Powerful induction by antigen coupled to cholera toxin B subunit
    • Sun, J. B., C. F. Flach, C. Czerkinsky, and J. Holmgren. 2008. B lymphocytes promote expansion of regulatory T cells in oral tolerance: powerful induction by antigen coupled to cholera toxin B subunit. J. Immunol. 181: 8278-8287.
    • (2008) J. Immunol. , vol.181 , pp. 8278-8287
    • Sun, J.B.1    Flach, C.F.2    Czerkinsky, C.3    Holmgren, J.4
  • 54
    • 1342268100 scopus 로고    scopus 로고
    • Use of the inactivated intranasal influenza vaccine and the risk of Bell's palsy in Switzerland
    • Mutsch, M., W. Zhou, P. Rhodes, M. Bopp, R. T. Chen, T. Linder, C. Spyr, and R. Steffen. 2004. Use of the inactivated intranasal influenza vaccine and the risk of Bell's palsy in Switzerland. N. Engl. J. Med. 350: 896-903.
    • (2004) N. Engl. J. Med. , vol.350 , pp. 896-903
    • Mutsch, M.1    Zhou, W.2    Rhodes, P.3    Bopp, M.4    Chen, R.T.5    Linder, T.6    Spyr, C.7    Steffen, R.8
  • 55
    • 66449089456 scopus 로고    scopus 로고
    • Role of CTA1R7K-COL-DD as a novel therapeutic mucosal tolerance-inducing vector for treatment of collagen-induced arthritis
    • Hasselberg, A., K. Schön, A. Tarkowski, and N. Lycke. 2009. Role of CTA1R7K-COL-DD as a novel therapeutic mucosal tolerance-inducing vector for treatment of collagen-induced arthritis. Arthritis Rheum. 60: 1672-1682.
    • (2009) Arthritis Rheum. , vol.60 , pp. 1672-1682
    • Hasselberg, A.1    Schön, K.2    Tarkowski, A.3    Lycke, N.4
  • 56
    • 33644885429 scopus 로고    scopus 로고
    • Antigen-induced, tolerogenic CD11c+,CD11b+ dendritic cells are abundant in Peyer's patches during the induction of oral tolerance to type II collagen and suppress experimental collagen-induced arthritis
    • Min, S. Y., K. S. Park, M. L. Cho, J. W. Kang, Y. G. Cho, S. Y. Hwang, M. J. Park, C. H. Yoon, J. K. Min, S. H. Lee, et al. 2006. Antigen-induced, tolerogenic CD11c+,CD11b+ dendritic cells are abundant in Peyer's patches during the induction of oral tolerance to type II collagen and suppress experimental collagen-induced arthritis. Arthritis Rheum. 54: 887-898.
    • (2006) Arthritis Rheum. , vol.54 , pp. 887-898
    • Min, S.Y.1    Park, K.S.2    Cho, M.L.3    Kang, J.W.4    Cho, Y.G.5    Hwang, S.Y.6    Park, M.J.7    Yoon, C.H.8    Min, J.K.9    Lee, S.H.10
  • 57
    • 0035425422 scopus 로고    scopus 로고
    • Designer dendritic cells for tolerance induction: Guided not misguided missiles
    • Hackstein, H., A. E. Morelli, and A. W. Thomson. 2001. Designer dendritic cells for tolerance induction: guided not misguided missiles. Trends Immunol. 22: 437-442.
    • (2001) Trends Immunol. , vol.22 , pp. 437-442
    • Hackstein, H.1    Morelli, A.E.2    Thomson, A.W.3
  • 60
    • 57449111504 scopus 로고    scopus 로고
    • Dendritic cells modulated by innate immunity improve collagen-induced arthritis and induce regulatory T cells in vivo
    • Jaen, O., S. Rulle, N. Bessis, A. Zago, M. C. Boissier, and G. Falgarone. 2008. Dendritic cells modulated by innate immunity improve collagen-induced arthritis and induce regulatory T cells in vivo. Immunology 126: 35-44.
    • (2008) Immunology , vol.126 , pp. 35-44
    • Jaen, O.1    Rulle, S.2    Bessis, N.3    Zago, A.4    Boissier, M.C.5    Falgarone, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.