Human papillomavirus L1 capsid protein and human papillomavirus type 16 as prognostic markers in cervical intraepithelial neoplasia 1

International Journal of Gynecological Cancer

Volumn 20, Issue 2, 2010, Pages 288-293

  Choi, Young Sam ^a   Kang, Woo Dae ^a   Kim, Seok Mo ^a   Choi, Yoo Duk ^a   Nam, Jong Hee ^a   Park, Chang Soo ^a   Choi, Ho Sun ^a  

^a Chonnam National University   (South Korea)

Author keywords

Biomarker; CIN; HPV 16; L1 capsid protein; Prognostic marker

Indexed keywords

CAPSID PROTEIN L1; CAPSID PROTEIN; HPV L1 PROTEIN, HUMAN PAPILLOMAVIRUS; ONCOPROTEIN; TUMOR MARKER;

ADULT; AGED; ARTICLE; CANCER REGRESSION; CONTROLLED STUDY; DISEASE COURSE; FEMALE; FOLLOW UP; GENOTYPE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFECTION RISK; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; UTERINE CERVIX CARCINOMA; VIRUS INFECTION; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; UTERINE CERVIX; UTERINE CERVIX CARCINOMA IN SITU; UTERINE CERVIX TUMOR; VIROLOGY;

ADULT; AGED; CAPSID PROTEINS; CERVICAL INTRAEPITHELIAL NEOPLASIA; CERVIX UTERI; DISEASE PROGRESSION; FEMALE; GENOTYPE; HUMAN PAPILLOMAVIRUS 16; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; ONCOGENE PROTEINS, VIRAL; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL; UTERINE CERVICAL NEOPLASMS;

EID: 77951884047     PISSN: 1048891X     EISSN: None     Source Type: Journal    
DOI: 10.1111/IGC.0b013e3181cd184c     Document Type: Article

References (24)

1. World Health Organization, Department of Reproductive Health and Research and Department of Chronic Diseases and Health Promotion. Integrating health care for sexual and reproductive health and chronic disease: Comprehensive cervical cancer control: A guide to essential practive [WHO Web site]. 2006. Available at http://www.who.int/reproductivehealth/publications/cancers/ 9241547006/en/index.html. Accessed November 11, 2008.
2. Addis IB, Hatch KD, Berek JS. Intraepithelial disease of the cervix, vagina and vulva. In: Berek JS, ed. Berek and Novak's Gynecology. 14th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2006:561-599.
3. Melsheimer P, Kaul S, Dobeck S, et al. Immunocytochemical detection of HPV high-risk type L1 capsid proteins in LSIL and HSIL as compared with detection of HPV L1 DNA. Acta Cytol. 2003;47:124-128.
4. Hilfrich R, Hariri J. Prognostic relevance of HPV L1 capsid protein detection within mild and moderate dysplastic lesions of the cervix uteri in combination with a second biomarker p16. Anal Quant Cytol Histol. 2008;30:78-82.
5. Rauber D, Mehlhorn G, Fasching PA, et al. Prognostic significance of the detection of human papilloma virus L1 protein in smears of mild to moderate cervical intraepithelial lesions. Eur J Obstet Gynecol Reprod Biol. 2008;140:258-262.
6. Griesser H, Sander H, Hilfrich R, et al. Correlation of immunochemical detection of HPV L1 capsid protein in pap smears with regression of high-risk HPV positive mild/moderate dysplasia. Anal Quant Cytol Histol. 2004;26:241-245.
7. Kirnbauer R, Booy F, Cheng N, et al. Papillomavirus L1 major capsid protein self-assembles into virus-like particles that are highly immunogenic. Proc Natl Acad Sci U S A. 1992;89:12180-12184.
8. Amina E, Hamoudi RA, Gabrijela K, et al. Cervical intraepithelial neoplasia: prognosis by combined LOH analysis of multiple loci. Gynecol Oncol. 2004;94:671-679.
9. Kruse AJ, Baak JP, Janssen EA, et al. Low-and high-risk CIN1 and 2 lesions: prospective predictive value of grade, HPV, and Ki-67 immuno-quantitative variables. J Pathol. 2003;199:462-470.
10. Baak JP, Kruse AJ, Robboy SJ, et al. Dynamic behavioural interpretation of cervical intraepithelial neoplasia with molecular biomarkers. J Clin Pathol. 2006;59:1017-1028.
11. Kawana K, Yasugi T, Kanda T, et al. Neutralizing antibodies against oncogenic human papillomavirus as a possible determinant of the fate of low-grade cervical intraepithelial neoplasia. Biochem Biophys Res Commun. 2002;296:102-105.
12. Falls RK. Spontaneous resolution rate of grade 1 cervical intraepithelial neoplasia in a private practice population. Am J Obstet Gynecol. 1999;181:278-282.
13. Kjaer SK, van den Brule AJ, Paull G, et al. Type specific persistence of high risk human papillomavirus (HPV) as indicator of high grade cervical squamous intraepithelial lesions in young women: population based prospective follow up study. BMJ. 2002;325:572.
14. Walboomers JM, Jacobs MV, Manos MM, et al. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol. 1999;189:1-3.
15. Gaarenstroom KN, Melkert P, Walboomers JM, et al. Human papillomavirus DNA and genotypes: prognostic factors for progression of cervical intraepithelial neoplasia. Int J Gynecol Cancer. 1994;4:73-78.
16. Hausen HZ, Gissmann L, Schlehofer JR. Viruses in the etiology of human genital cancer. Prog Med Virol. 1984;30:170-186.
17. Etherington IJ, Ellis JR, Luesley DM, et al. Histologic and immunologic associations of an HPV16 variant in LoSIL Smears. Gynecol Oncol. 1999;72:56-59.
18. Stö ppler MC, Ching K, Stö ppler H, et al. Natural variants of the human papillomavirus type 16 E6 protein differ in their abilities to alter keratinocyte differentiation and to induce p53 degradation. J Virol. 1996;70:6987-6993.
19. Koshiol JE, Schroeder JC, Jamieson DJ, et al. Time to clearance of human papillomavirus infection by type and human immunodeficiency virus serostatus. Int J Cancer. 2006;119:1623-1629.
20. Kanodia S, Fahey LM, Kast WM. Mechanisms used by human papillomaviruses to escape the host immune response. Curr Cancer Drug Targets. 2007;7:79-89.
21. Wright TC Jr, Massad LS, Dunton CJ, et al. 2006 consensus guidelines for the management of women with abnormal cervical cancer screening tests. Am J Obstet Gynecol. 2007;197:346-355.
22. Lee HS, Kim SM, Choi HS, et al. Human papillomavirus genotyping using HPV DNA chip analysis in Korean women. Int J Gynecol Cancer. 2007;17:497-501.
23. Choi YD, Nam JH, Park CS, et al. Detection of HPV genotypes in cervical lesions by the HPV DNA Chip and sequencing. Gynecol Oncol. 2005;98:369-375.
24. Luisa V. Biology of genital human papillomaviruses. Int J Gynecol Obstet. 2006;94: S3-S7.