Role of intravenous naloxone in severe pruritus of acute cholestasis

Indian Journal of Gastroenterology

Volumn 28, Issue 5, 2009, Pages 180-182

  Joshi, Gunjan G ^a   Thakur, B S ^a   Sircar, Shohini ^a   Namdeo, Arvind ^a   Jain, Ajay K ^a  

^a CHOITHRAM HOSPITAL AND RESEARCH CENTRE   (India)

Author keywords

Cholestasis; Naloxone; Open label study

Indexed keywords

ALKALINE PHOSPHATASE; BILIRUBIN; GAMMA GLUTAMYLTRANSFERASE; NALOXONE;

ABSENCE OF SIDE EFFECTS; ADULT; ALKALINE PHOSPHATASE BLOOD LEVEL; ARTICLE; BILIRUBIN BLOOD LEVEL; BOLUS INJECTION; BREAKTHROUGH PHENOMENON; CHOLESTASIS; CLINICAL ARTICLE; CLINICAL TRIAL; CYTOMEGALOVIRUS INFECTION; DISEASE ASSOCIATION; DISEASE SEVERITY; DRUG EFFICACY; DRUG RESPONSE; DRUG SAFETY; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HEPATITIS A; HEPATITIS B; HEPATITIS E; HERPES SIMPLEX; HUMAN; MALE; PROSPECTIVE STUDY; PRURITUS; SHORT COURSE THERAPY; SYMPTOM; VIRUS HEPATITIS; VISUAL ANALOG SCALE; ACUTE DISEASE; INTRAVENOUS DRUG ADMINISTRATION;

ACUTE DISEASE; ADULT; CHOLESTASIS; FEMALE; HUMANS; INJECTIONS, INTRAVENOUS; MALE; NALOXONE; PROSPECTIVE STUDIES; PRURITUS;

EID: 77951882324     PISSN: 02548860     EISSN: 02548860     Source Type: Journal    
DOI: 10.1007/s12664-009-0070-8     Document Type: Article

References (9)

1. Greaves MW, Wall PD. Pathophysiology of itching. Lancet 1996;348:938-40.
2. Ballantyne JC, Loach AB, Carr DB. The incidence of pruritus after epidural morphine. Anesthesia 1989;44:863.
3. Koenigstein H. Experimental study of itch stimuli in animals. Arch Dermatol Syphilol 1948;57:828-49.
4. Jaffe J, Martin W. Opioid analgesics and antagonists. In: Gilman A, Goodman L, Rall T (eds). The Pharmacologic Basis of Therapeutics. 7th ed. New York: Macmillan;1985: 491-531.
5. Oliveras JL, Maixner W, Dubner R, et al. The medullary dorsal horn: a target for the expression of opiate effects on the perceived intensity of noxious heat. J Neurosci 1986;6:3086-93.
6. Ballantyne JC, Loach AB, Carr DB. Itching after epidural and spinal opiates. Pain 1988;33:149-60.
7. Thomas DA, Williams GM, Iwata K, Kenshalo DR Jr, Dubner R. Effects of central administration of opioids on facial scratching in monkeys. Brain Res 1992;585: 315-7.
8. Bergasa NV, Talbot TL, Alling DW, et al. A controlled trial of naloxone infusions for the pruritus of chronic cholestasis. Gastroenterology 1992;102:544-9.
9. Bergasa NV, Alling DW, Talbot TL, et al. Effects of naloxone infusions in patients with the pruritus of cholestasis. A double blind randomized controlled trial. Ann Intern Med 1995;123:161-7.