Polyvalent horse F(Ab')2 snake antivenom: Development of process to produce polyvalent horse F(Ab')2 antibodies anti-african snake venom

African Journal of Biotechnology

Volumn 9, Issue 16, 2010, Pages 2446-2455

  Guidlolin, R G ^a   Marcelino, R M ^a   Gondo, H H ^a   Morais, J F ^a   Ferreira, R A ^b   Silva, C L ^b   Kipnis, T L ^b   Silva, J A ^b   Fafetine, J ^c   da Silva, W D ^b  

^a INSTITUTO BUTANTAN   (Brazil)

^b UNIVERSIDADE ESTADUAL DO NORTE FLUMINENSE DARCY RIBEIRO   (Brazil)

^c EDUARDO MONDLANE UNIVERSITY   (Mozambique)

Author keywords

African snake venoms; Antivenoms; Envenoming; F(ab')2 fragments; Immunoglobulin IgG(T); Immunotherapy

Indexed keywords

AMMONIUM SULFATE; IMMUNOGLOBULIN ANTIBODY; IMMUNOGLOBULIN F(AB')2 FRAGMENT ANTIBODY; IMMUNOGLOBULIN G; PEPSIN A; SNAKE VENOM; SNAKE VENOM ANTISERUM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ANTIBODY TITER; ARTICLE; BIOTECHNOLOGICAL PRODUCTION; CHROMATOGRAPHY; CONTROLLED STUDY; DRUG QUALITY; ELECTROPHORESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HORSE; IMMUNIZATION; IMMUNOGLOBULIN STRUCTURE; MALE; MOUSE; NONHUMAN; ULTRAFILTRATION; WESTERN BLOTTING;

BACTERIA (MICROORGANISMS); BITIS; BITIS ARIETANS; BITIS NASICORNIS; BITIS RHINOCEROS; EQUIDAE; NAJA; NAJA MELANOLEUCA; NAJA MOSSAMBICA;

EID: 77951763380     PISSN: 16845315     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Almeida CMC, Silva CL, Pena-Couto H, Escocard RCM, Rocha DG, Sentinelli LP, Kipnis TL, da-Silva WD (2008). Development of Process to Produce Polyvalent IgY Antibodies Anti-African Snake Venom. Toxicon. doi.10,1016/j.toxicon. 05.022-026.
2. Broadley CM (1968). The venemous snakes in Central and South Africa. In: Bücherl, W, Buckley E, Deulofeu V (eds) Venomous Animals and Their Venoms. Academic Press, New York, London, I, pp. 433-436.
3. Brown JH (1973). Toxicology and pharmacology of venoms from poisonous snakes. Springfield, Charles C. Thomas, Illinois, pp. 184-188.
4. Calmette A (1894). Límmunisation artificelle des animaux contre le venin des serpents et la therapeutic experimentale de morsures venimeuses. CR Soc. Biol. 46: 120-124.
5. Committee Members, International Society on Toxinology Toxicon (1992). pp. 30: 1-12.
6. Finney DJ (1992). Probit Analysis. Third edition. Cambridg, UK: Cambridge University Press.
7. Herbert WJ (1978). In: Weir, DM ed, Handbook of Experimental Immunology -Appendices 3 DM. (A 3.8ed. Weir. Blakweel Sientific Publications, England, Oxford.
8. Laemmili UK (1970). Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature, 227: 680-685.
9. Mallow D, Ludwig D, Nilsson G (2003). True Vipers: Natural History and Toxicology of Old World Vipers. Krieger Publishing Company, Malabar, Florida. pp. 359-363.
10. Manacas S (1981/1982). Ofídeos venenosos da Guine, S. Tome, Angola e Mocambique. Garcia de Orta, Ser. Zoo. Lisboa. 10(1-2): 13-46.
11. Nisonoff A (1973). The antibody molecule. Academic Press, New York.
12. Outchterloni O, Nilson LÄ (1986). Immunodiffusion and immunioelectrophoresis. In: Handbook of Experimental Immunology, Weir DM, Herzenberg LA (eds), 4e, Section 32, Blackwell Scientific Publishing, Oxford.
13. Ponte CG, Nobrega L, Fernandes VC, Dias da Silva W, Suarez-Kurtz G. (2009). Inhibition of the myotoxic activities of three African Bitis venoms (arietans, nasicornis and rhinoceros) by Brazilian polyvalent antivenom. Toxicon. Accepted for publication.
14. Reid HA (1964). Cobra bites. Br. Med. J. II: 540-545.
15. Remfry J (1987). Ethical aspects of animal experimentation. In: Tuffery AA (Editor), Laboratory animals: an introduction for new experimenters. Interscience, New York, pp. 5-9.
16. Segura A, Villalta M, Herrera M, León G et al (2009). Preclinical assessment of the efficacy of a new antivenom (EchiTaAb-Plus-ICP® for treatment of viper anvenoming in sub-Saharan Africa. Toxicon. (doi:10.10-16).
17. Sewall H (1887). Experiments on the preventive inoculation of rattlesnake venom. J. Physiol Lond.8:203-210.
18. Spawls S, Branch B (1995). The Dangerous Snakes of Africa. Ralph Curtis Books. Dubai iental Press: pp. 192-196.
19. Spaws SK, Drewes R, Ashe JA (2004). Field guide to the reptiles of East Africa. A & C Black Publishers Ltd., London, pp. 543-549.
20. Theakston RDG (1996). Clinical features of envenoming from snake bites. In: Bon C and Goyffon M (eds). Envenomings and their treatments. Fondation Marcel Merrieux, pp. 117-126.
21. Theakston RGD, Warrell DA, Griffiths E (2003). Report of a WHO workshop on the standardization and control of antivenoms. Toxicon, 41(5): 541-557.
22. Towbin H, Staechelin T, Gordon J (1979). Electrophoretic transfer of proteins from polyacrilamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Natl. Acad. Sci. USA. 76: 4350-4354.
23. Navy US (1991). Poisonous snakes of the world. US Govt New York: Dover Publications Inc. pp. 203-206.
24. Viravan C, Veeravat U, Warrell MJ, Theakston RDG, Warrell DA (1986). ELISA confirmation of acute and past envenoming by the monocellate Thai cobra (Naja kaouthia). Am. J. Trop. Med. Hyg. 35: 173-182.
25. Warrell DA, Ormendand LD, Davidson NMC (1975). Bites by puff-adder (B. arietans) in Nigeria and value of antivenom. Br. M J. 4: 697-700.
26. Warrell DA, Arnett C (1976). The importance of bites by the saw-scaled or garpet viper (Echis carinatus). Epidemiological studies in Nigeria and a review of the world literature. Acta Tropica (Basel), 33: 307-341.
27. Warrell DA (1996). Clinical features of envenoming from snake bites In: Bon C, Goyffon M (eds). Envenomings and their treatments. Fondation Marcel Merrieux, pp. 64-76.
28. World Health Organization (1981). Progress in the Characterization of Venoms and Standardization of Antivenoms, (WHO Offset Publication No 58). Geneva.