Multiphoton microscopy as a diagnostic imaging modality for lung cancer

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 7569, Issue , 2010, Pages

  Pavlova, Ina ^a   Hume, Kelly R ^b   Yazinski, Stephanie A ^b   Peters, Rachel M ^b   Weiss, Robert S ^b   Webb, Watt W ^a  

^a Cornell University   (United States)

^b Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL MODEL; COMPUTED TOMOGRAPHY; CURRENT DIAGNOSTICS; DIAGNOSTIC IMAGING; EARLY DIAGNOSIS; EX-VIVO; EXPERIMENTAL APPROACHES; FLUORESCENCE DETECTION; FLUORESCENCE EMISSION; HUMAN LUNG; IN-VIVO; IN-VIVO IMAGING; INTRINSIC FLUORESCENCE; LONG-TERM GOALS; LUNG ABNORMALITIES; LUNG CANCER; LUNG TISSUE; MULTI-CHANNEL; MULTIPHOTON MICROSCOPY; MULTIPHOTONS; MURINE MODEL; OPTICAL GUIDANCE; SECOND HARMONIC GENERATION; SMALL LESIONS; SPECTRAL IMAGING; SPECTROSCOPIC INFORMATION; SURVIVAL RATE; TWO-PHOTON EXCITED;

COMPUTERIZED TOMOGRAPHY; FLUORESCENCE; HARMONIC GENERATION; NONLINEAR OPTICS; TISSUE;

BIOLOGICAL ORGANS;

EID: 77951762698     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.841017     Document Type: Conference Paper

References (23)

1. Jemal, A., Siegel, R., Ward, E., Hao, Y.P., Xu, J.Q., Murray, T. and Thun, M.J., "Cancer statistics, 2008," Ca-Cancer J Clin 58, 71-96 (2008).
2. Schreiber, G. and McCrory, D.C., "Performance characteristics of different modalities for diagnosis of suspected lung cancer - Summary of published evidence," Chest 123, 115S-128S (2003). (Pubitemid 36135709)
3. Montaudon, M., Latrabe, V., Pariente, A., Corneloup, O., Begueret, H. and Laurent, F., "Factors influencing accuracy of CT-guided percutaneous biopsies of pulmonary lesions," Eur Radiol 14, 1234-1240 (2004). (Pubitemid 38979217)
4. Meyer, C., "Transthoracic Needle Aspiration Biopsy of Benign and Malignant Lung Lesions - A Commentary," AJR 188, 891-893 (2007). (Pubitemid 46496914)
5. Khouri, N.F., Stitik, F.P., Erozan, Y.S., Gupta, P.K., Kim, W.S., Scott, W.W., Hamper, U.M., Mann, R.B., Eggleston, J.C. and Baker, R.R., "Transthoracic needle aspiration biopsy of benign and malignant lung lesions," AJR 144, 281-288 (1985).
6. Kiesslich, R., Goetz, M. and Neurath, M.F., "Confocal laser endomicroscopy for gastrointestinal diseases," Gastrointestinal Endoscopy Clinics of North America 18(3), 451-466 (2008).
7. Myaing, M.T., MacDonald, D.J. and Li, X., "Fiber-optic scanning two-photon fluorescence endoscope," Opt. Lett. 31, 1076-1078 (2006). (Pubitemid 43837457)
8. Levene, M.J., Dombeck, D.A., Molloy, R.P., Kasischke, K.A., Williams, R.M., Zipfel, W.R. and Webb, W.W., "In vivo multiphoton microscopy of deep brain tissue," Journal of Neurophysiology 91, 1908-1912 (2004).
9. Barretto, R.P.J., Messerschmidt, B. and Schnitzer, M.J., "In vivo fluorescence imaging with high-resolution microlenses," Nature Methods 6(7), 511-512 (2009).
10. Denk, W., Strickler, J.H. and Webb, W.W., "Two-Photon Laser Scanning Fluorescence Microscopy," Science 248, 73-76 (1990). (Pubitemid 20139273)
11. Zipfel, W.R., Williams, R.M. and Webb, W.W., "Nonlinear Magic: Multiphoton Microscopy in the Biosciences," Nature Biotechnology 21, 1369-1377 (2003).
12. Kwan, A.C., Duff, K., Gouras, G.K. and Webb, W.W., "Optical visualization of Alzheimer's pathology via multiphoton-excited intrinsic fluorescence and second harmonic generation," Opt Express 17, 3679-3689 (2009).
13. Kasischke, K.A., Vishwasrao, H.D., Fisher, P.J., Zipfel, W.R. and Webb, W.W., "Neural activity triggers neuronal oxidative metabolism followed by astrocytic glycolysis," Science 305, 99-103 (2004).
14. Zipfel, W.R., Williams, R.M., Christie, R.H., Nikitin, A.Y., Hyman, B.T. and Webb, W.W., "Live Tissue Intrinsic Emission Microscopy Using Multiphoton Excited Intrinsic Fluorescence and Second Harmonic Generation," PNAS 100, 7075-7080 (2003).
15. Vishwasrao H. D., Heikal A. A., Kasischke K.A., and Webb W. W., "Conformational Dependence of Intracellular NADH on Metabolic State Revealed by Associated Fluorescence Anisotropy," JBC, 280 (26), 25119-25126 (2005).
16. Mukherjee, S., Wysock, J.S., Ng, C.K., Akhtar, M., Perner, S., Lee, M.-M., Rubin, M.A., Maxfield, F.R., Webb, W.W. and Scherr, D.S., "Human bladder cancer diagnosis using Multiphoton microscopy," Proceedings of SPIE 7161, 716117-1716111 to 716117-716110 (2009).
17. Rogart, J. N., Nagata, J., Loeser, C. S., Roorda, R. D., Aslanian, H., Robert, M. E., Zipfel, W. R. and Nathanson, M. H., "Multiphoton imaging can be used for microscopic examination of intact human gastrointestinal mucosa ex vivo," Clin Gastroenterol Hepatol 6, 95-101 (2008). (Pubitemid 50009249)
18. Conti C.J., "Atlas of Laboratory Mouse Histology", http://ctrgenpath.net/atlas/mouseHistology, (2009)
19. Pena, A., Fabre, A., Debarre, D., Marchal-Somme, J.,Crestani, Martin, J., Beaurepaire, E. and Schanne-Klein, M., "Three-Dimensional investigation and scoring of extracellular matrix remodeling during lung fibrosis using multiphoton microscopy," Microscopy Research and Technique 70, 162-170 (2007). (Pubitemid 46292251)
20. Wang, C.C., Li, F.C., Wu, R.J., Hovhannisyan, V.A., Lin, W.C., Lin, S.J., So, P.T.C. and Dong, C.Y., "Differentiation of normal and cancerous lung tissues by multiphoton imaging," Journal of Biomedical Optics 14 (4), 044034 (2009).
21. Xu, X., Page, J.L., Surtees, J.A., Liu, H.C., Lagedrost, S., Li, Y., Bronson, R., Alani, E., Nikitin, A.Y. and Weiss, R.S., "Broad overexpression of ribonucleotide reductase genes in mice specifically induces lung neoplasms," Cancer Res 68, 2652-2660 (2008). (Pubitemid 351556262)
22. Jackson, E.L., Willis, N., Mercer, K., Bronson, R.T., Crowley, D., Montoya, R., Jacks, T. and Tuveson, D.A., "Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras," Genes Dev 15, 3243-3248 (2001). (Pubitemid 34008190)
23. Nikitin, A.Y., Alcaraz, A., Anver, M.R., Bonson, R.T., Cardiff, R.D., Dixon, D., Fraire, A.E., Gabrielson, E.W., Gunning, W.T., Haines, D.C., Kaufman, M.H., Linnoila, R.I., Maronpot, R.R., Rabson, A.S., Reddick, R.L., Rehm, S., Rozengurt, N., Schuller, H.M., Shmidt, E.N., Travis, W.D., Ward, J.M. and Jacks, T., "Classification of proliferative pulmonary lesions of the mouse: Recommendations of the mouse models of human cancers consortium," Cancer Res 64, 2307-2316 (2004). (Pubitemid 38523879)