Rational design and synthesis of 4-O-substituted phenylmethylenethiosemicarbazones as novel tyrosinase inhibitors

Chemical and Pharmaceutical Bulletin

Volumn 58, Issue 5, 2010, Pages 752-754

  Yi, Wei ^a   Cao, Rihui ^a   Chen, Zhiyong ^a   Yu, Liang ^a   Wen, Huan ^a   Yan, Qin ^a   Ma, Lin ^a   Song, Huacan ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

4 O substituted phenylmethylenethiosemicarbazone; Synthesis; The structure activity relationship; Tyrosinase inhibitory activity

Indexed keywords

4 HYDROXYBENZALDEHYDE; ENZYME INHIBITOR; MONOPHENOL MONOOXYGENASE; THIOSEMICARBAZIDE; THIOSEMICARBAZONE DERIVATIVE; TROPOLONE;

ARTICLE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; IC 50; MUSHROOM; STRUCTURE ACTIVITY RELATION;

AGARICALES; DRUG DESIGN; ENZYME INHIBITORS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; MONOPHENOL MONOOXYGENASE; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; THIOSEMICARBAZONES;

EID: 77951707743     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.58.752     Document Type: Article

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