Coordinated regulation of dorsal bone morphogenetic protein 4 and ventral Sonic hedgehog signaling specifies the dorso-ventral polarity in the optic vesicle and governs ocular morphogenesis through fibroblast growth factor 8 upregulation

Development Growth and Differentiation

Volumn 52, Issue 4, 2010, Pages 351-363

  Kobayashi, Takuma ^a,b   Yasuda, Kunio ^b   Araki, Masasuke ^a  

^a NARA WOMEN'S UNIVERSITY   (Japan)

^b NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

BMP4; Chick embryo; Dorso ventral polarity; FGF8; Ocular development; Optic vesicle; Organ culture; Shh

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; FIBROBLAST GROWTH FACTOR 8; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR PAX2; TRANSCRIPTION FACTOR TBX5;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; EYE DEVELOPMENT; GENE EXPRESSION; GROWTH REGULATION; LENS; MORPHOGENESIS; NONHUMAN; PIGMENT EPITHELIUM; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; BODY PATTERNING; BONE MORPHOGENETIC PROTEIN 4; BRAIN; CHICK EMBRYO; EYE; FIBROBLAST GROWTH FACTOR 8; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEDGEHOG PROTEINS; IN SITU HYBRIDIZATION; MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR; ORGAN CULTURE TECHNIQUES; OTX TRANSCRIPTION FACTORS; PAX2 TRANSCRIPTION FACTOR; RETINAL PIGMENT EPITHELIUM; SIGNAL TRANSDUCTION; T-BOX DOMAIN PROTEINS;

ERINACEIDAE; VERTEBRATA;

EID: 77951704064     PISSN: 00121592     EISSN: 1440169X     Source Type: Journal    
DOI: 10.1111/j.1440-169X.2010.01170.x     Document Type: Article

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