Cellular basis for the olfactory response to nicotine

ACS Chemical Neuroscience

Volumn 1, Issue 3, 2010, Pages 246-256

  Bryant, Bruce ^a   Xu, Jiang ^a   Audige, Valery ^b   Lischka, Fritz W ^a   Rawson, Nancy E ^c  

^a MONELL CHEMICAL SENSES CENTER   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c WellGen Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CALCIUM; NICOTINE; NICOTINIC RECEPTOR;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; NERVE CELL; NERVE STIMULATION; NONHUMAN; OLFACTORY EPITHELIUM; OLFACTORY NERVE; OLFACTORY RECEPTOR; PATCH CLAMP; RAT; SENSORY NERVE CELL; STEREOCHEMISTRY;

ADENYLATE CYCLASE; CYCLIC NUCLEOTIDE GATED CHANNEL; ODOR; SMOKING; TOBACCO; TRANSDUCTION;

ANIMALS; BIOPSY; CALCIUM; CALCIUM SIGNALING; CELLS, CULTURED; CYCLIC AMP; EXTRACELLULAR SPACE; INDICATORS AND REAGENTS; NICOTINE; NICOTINIC AGONISTS; OLFACTORY RECEPTOR NEURONS; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NICOTINIC; SECOND MESSENGER SYSTEMS; SIGNAL TRANSDUCTION; SMELL; SMOKING; STEREOISOMERISM;

ANIMALIA; NICOTIANA TABACUM; RATTUS; RODENTIA;

EID: 77951701423     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn900042c     Document Type: Article

References (35)

1. Rose, J. E., Behm, F. M. and Levin, E. D. (1993) Role of nicotine dose and sensory cues in the regulation of smoke intake Pharmacol., Biochem. Behav. 44 (4) 891-900
2. Gomez, G., Rawson, N. E., Hahn, C. G., Michaels, R. and Restrepo, D. (2000) Characteristics of odorant elicited calcium changes in cultured human olfactory neurons J. Neurosci. Res. 62 (5) 737-749
3. Rose, J. E., Tashkin, D. P., Ertle, A., Zinser, M. C. and Lafer, R. (1985) Sensory blockade of smoking satisfaction Pharmacol., Biochem. Behav. 23 (2) 289-293
4. Perkins, K. A., Gerlach, D., Vender, J., Grobe, J., Meeker, J. and Hutchison, S. (2001) Sex differences in the subjective and reinforcing effects of visual and olfactory cigarette smoke stimuli Nicotine Tob. Res. 3 (2) 141-150
5. Westman, E. C., Behm, F. M. and Rose, J. E. (1995) Airway sensory replacement combined with nicotine replacement for smoking cessation. A randomized, placebo-controlled trial using a citric acid inhaler Chest 107 (5) 1358-1364
6. Pritchard, W. S., Robinson, J. H., Guy, T. D., Davis, R. A. and Stiles, M. F. (1996) Assessing the sensory role of nicotine in cigarette smoking Psychopharmacology 127 (1) 55-62
7. Naqvi, N. H. and Bechara, A. (2005) The airway sensory impact of nicotine contributes to the conditioned reinforcing effects of individual puffs from cigarettes Pharmacol., Biochem. Behav. 81 (4) 821-829
8. Thuerauf, N., Kaegler, M., Renner, B., Barocka, A. and Kobal, G. (2000) Specific sensory detection, discrimination, and hedonic estimation of nicotine enantiomers in smokers and nonsmokers: are there limitations in replacing the sensory components of nicotine? J. Clin. Psychopharmacol. 20 (4) 472-478
9. Thuerauf, N., Kaegler, M., Dietz, R., Barocka, A. and Kobal, G. (1999) Dose-dependent stereoselective activation of the trigeminal sensory system by nicotine in man Psychopharmacology 142 (3) 236-243
10. Thuerauf, N., Markovic, K., Braun, G., Bleich, S., Reulbach, U., Kornhuber, J. and Lunkenheimer, J. (2006) The influence of mecamylamine on trigeminal and olfactory chemoreception of nicotine Neuropsychopharmacology 31 (2) 450-461
11. Restrepo, D., Okada, Y., Teeter, J. H., Lowry, L. D., Cowart, B. and Brand, J. G. (1993) Human olfactory neurons respond to odor stimuli with an increase in cytoplasmic Ca2+ Biophys. J. 64 (6) 1961-1966
12. Tareilus, E., Noé, J. and Breer, H. (1995) Calcium signals in olfactory neurons Biochim. Biophys. Acta 1269 (2) 129-138
13. Cowart, B. J., Flynn-Rodden, K., McGeady, S. J. and Lowry, L. D. (1993) Hyposmia in allergic rhinitis J. Allergy Clin. Immunol. 91 (3) 747-751
14. Lowry, L. D. and Pribitkin, E. A. (1995) Collection of human olfactory tissue, in Experimental biology of taste and olfaction (Spielman, A. I. and Brand, J. G., eds), pp 47 - 48, CRC Press, Boca Raton, FL.
15. Rawson, N. E., Gomez, G., Cowart, B., Brand, J. G., Lowry, L. D., Pribitkin, E. A. and Restrepo, D. (1997) Selectivity and response characteristics of human olfactory neurons J. Neurophysiol. 77 (3) 1606-1613
16. Borgmann-Winter, K. E., Rawson, N. E., Wang, H. Y., Wang, H., Macdonald, M. L., Ozdener, M. H., Yee, K. K., Gomez, G., Xu, J., Bryant, B., Adamek, G., Mirza, N., Pribitkin, E. and Hahn, C. G. (2009) Human olfactory epithelial cells generated in vitro express diverse neuronal characteristics Neuroscience 158 (2) 642-653
17. Gomez, G., Lischka, F. W., Haskins, M. E. and Rawson, N. E. (2005) Evidence for multiple calcium response mechanisms in mammalian olfactory receptor neurons Chem. Senses 30 (4) 317-326
18. Lischka, F. W., Teeter, J. H. and Restrepo, D. (1999) Odorants suppress a voltage-activated K+ conductance in rat olfactory neurons J. Neurophysiol. 82 (1) 226-236
19. Ma, L. and Michel, W. C. (1998) Drugs affecting phospholipase C-mediated signal transduction block the olfactory cyclic nucleotide-gated current of adult zebrafish J. Neurophysiol. 79 (3) 1183-1192
20. Thastrup, O., Cullen, P. J., Drøbak, B. K., Hanley, M. R. and Dawson, A. P. (1990) Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase Proc. Natl. Acad. Sci. U.S.A. 87 (7) 2466-2470
21. Chen, S., Lane, A. P., Bock, R., Leinders-Zufall, T. and Zufall, F. (2000) Blocking adenylyl cyclase inhibits olfactory generator currents induced by 'IP(3)-odors' J. Neurophysiol. 84 (1) 575-580
22. Zhainazarov, A. B. and Ache, B. W. (1995) Odor-induced currents in Xenopus olfactory receptor cells measured with perforated-patch recording J. Neurophysiol. 74 (1) 479-483
23. Frings, S., Lynch, J. W. and Lindemann, B. (1992) Properties of cyclic nucleotide-gated channels mediating olfactory transduction. Activation, selectivity, and blockage J. Gen. Physiol. 100 (1) 45-67
24. 2(+)-dependent adaptive properties in the solitary olfactory receptor cell of the newt Brain Res. 515 (1-2) 261-268
25. Edwards, D. A., Mather, R. A., Shirley, S. G. and Dodd, G. H. (1987) Evidence for an olfactory receptor which responds to nicotine-nicotine as an odorant Experientia 43, 868-873
26. Hummel, T., Hummel, C., Pauli, E. and Kobal, G. (1992) Olfactory discrimination of nicotine-enantiomers by smokers and non-smokers Chem. Senses 17, 13-21
27. Mombaerts, P. (2004) Odorant receptor gene choice in olfactory sensory neurons: The one receptor-one neuron hypothesis revisited Curr. Opin. Neurobiol. 14 (1) 31-36 (Pubitemid 38264569)
28. Keiger, C. J., Case, L. D., Kendal-Reed, M., Jones, K. R., Drake, A. F. and Walker, J. C. (2003) Nicotinic cholinergic receptor expression in the human nasal mucosa Ann. Otol., Rhinol., Laryngol. 112 (1) 77-84
29. Walker, J. C., Kendal-Reed, M., Keiger, C. J., Bencherif, M. and Silver, W. S. (1996) Olfactory and trigeminal responses to nicotine Drug Dev. Res. 8, 160-168
30. Edwards, D. A., Mather, R. A. and Dodd, G. H. (1988) Spatial variation in response to odorants on the rat olfactory epithelium Experientia 44 (3) 208-211
31. Bouvet, J. F., Delaleu, J. C. and Holley, A. (1988) The activity of olfactory receptor cells is affected by acetylcholine and substance P Neurosci. Res. 5, 214-223
32. Nakamura, T. and Gold, G. H. (1987) A cyclic nucleotide-gated conductance in olfactory receptor cilia Nature 325 (6103) 442-444
33. Zufall, F., Shepherd, G. M. and Firestein, S. (1991) Inhibition of the olfactory cyclic nucleotide gated ion channel by intracellular calcium Proc. Biol. Sci. 246 (1317) 225-230
34. Nutter, T. J. and Adams, D. J. (1995) Monovalent and divalent cation permeability and block of neuronal nicotinic receptor channels in rat parasympathetic ganglia J. Gen. Physiol. 105 (6) 701-723
35. Hamon, B., Glowinski, J. and Giaume, C. (1997) Nicotine inhibits slowly inactivating K+ currents in rat cultured striatal neurons Pflugers Arch. 434 (5) 642-645