Use of a robust dehydrogenase from an archael hyperthermophile in asymmetric catalysis-dynamic reductive kinetic resolution entry into (s)-profens

Journal of the American Chemical Society

Volumn 132, Issue 17, 2010, Pages 5930-5931

  Friest, Jacob A ^a   Maezato, Yukari ^a   Broussy, Sylvain ^a   Blum, Paul ^a   Berkowitz, David B ^a  

^a UNIVERSITY OF NEBRASKA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDES; CATALYST ACTIVITY; CHAINS; ENZYMES; LITHIUM COMPOUNDS; RECYCLING; SUBSTRATES;

ALCOHOL DEHYDROGENASE; ASYMMETRIC CATALYSIS; ASYMMETRIC SYNTHESIS; BUTYL PROPIONATES; HETEROLOGOUS EXPRESSION; KINETIC RESOLUTION; NON-STEROIDAL ANTI-INFLAMMATORY DRUGS; SULFOLOBUS SOLFATARICUS;

DRUG PRODUCTS;

ALCOHOL DEHYDROGENASE; BACTERIAL ENZYME; FENOPROFEN; FLURBIPROFEN; IBUPROFEN; KETOPROFEN; NAPROXEN; OXIDOREDUCTASE;

ARCHAEBACTERIUM; ARTICLE; ASYMMETRIC CATALYSIS; ASYMMETRIC SYNTHESIS; ENANTIOSELECTIVITY; ENZYME STRUCTURE; ENZYME SYNTHESIS; HYPERTHERMOPHILE; MOLECULAR DOCKING; NONHUMAN; PHYLOGENY; REDUCTION KINETICS; SULFOLOBUS SOLFATARICUS;

EID: 77951687148     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja910778p     Document Type: Article

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