Zinc Mesoporphyrin Induces Rapid Proteasomal Degradation of Hepatitis C Nonstructural 5A Protein in Human Hepatoma Cells

Gastroenterology

Volumn 138, Issue 5, 2010, Pages

  Hou, Weihong ^a,b   Tian, Qing ^a   Zheng, Jianyu ^a,b   Bonkovsky, Herbert L ^a,b,c,d  

^a CAROLINAS MEDICAL CENTER   (United States)

^b UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

Hepatitis C Virus; NS5A; Ubiquitination; Zinc Mesoporphyrin

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; EPOXOMICIN; MESOPORPHYRIN; NONSTRUCTURAL PROTEIN 5A; PROTEASOME; ZINC;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY TEST; DOWN REGULATION; HALF LIFE TIME; HEPATITIS C; HEPATITIS VIRUS; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN STABILITY; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA REPLICATION; UBIQUITINATION; VIRUS REPLICATION; WESTERN BLOTTING;

EID: 77951666248     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2009.11.001     Document Type: Article

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