LH concentrations do not correlate with pregnancy in rFSH/GnRH antagonist cycles

Reproductive BioMedicine Online

Volumn 20, Issue 4, 2010, Pages 565-567

  Doody, Kevin ^a   Devroey, Paul ^b   Gordon, Keith ^c   Witjes, Han ^c   Mannaerts, Bernadette ^c  

^a Center for Assisted Reproduction   (United States)

^b CENTRE FOR REPRODUCTIVE MEDICINE   (Belgium)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Endogenous LH; GnRH antagonist protocol; IVF; rFSH

Indexed keywords

CHORIONIC GONADOTROPIN; CORIFOLLITROPIN ALFA; GANIRELIX; GONADORELIN ANTAGONIST; LUTEINIZING HORMONE; RECOMBINANT FOLLITROPIN; UNCLASSIFIED DRUG;

ARTICLE; CLINICAL ASSESSMENT; CLINICAL TRIAL; CONCENTRATION (PARAMETERS); CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; HUMAN; LABORATORY; MULTICENTER STUDY; OUTCOME ASSESSMENT; OVARY; PREGNANCY; PREGNANCY RATE; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL; STIMULATION;

EID: 77951652734     PISSN: 14726483     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rbmo.2009.12.019     Document Type: Article

References (7)

1. Bosch, E., Escudero, E., Crespo, J., et al., 2005. Serum luteinizing hormone in patients undergoing ovarian stimulation with gonadotropin-releasing hormone antagonists and recombinant follicle-stimulating hormone and its relationship with cycle outcome. Fertil. Steril. 84, 1529-1532.
2. Bosch, E., Vidal, C., Labarta, E., et al., 2008. Highly purified hMG versus recombinant FSH in ovarian hyperstimulation with GnRH antagonists - a randomized study. Hum. Reprod. 23, 2346-2351.
3. Cédrin-Durnerin, I., Grange-Dujardin, D., Laffy, A., et al., 2004. Recombinant human LH supplementation during GnRH antagonist administration in IVF/ICSI cycles: a prospective randomized study. Hum. Reprod. 19, 1979-1984.
4. Devroey, P., Boostanfar, R., Koper, N.P., et al., for the ENGAGE Investigators, 2009. A double-blind, non-inferiority, RCT comparing corifollitropin alfa and recombinant FSH during the first seven days of ovarian stimulation using a GnRH antagonist protocol. Hum. Reprod. 24, 3063-3072.
5. Griesinger, G., Schultze-Mosgau, A., Dafopoulos, K., et al., 2005. Recombinant luteinizing hormone supplementation to recombinant follicle-stimulating hormone induced ovarian hyperstimulation in the GnRH-antagonist multiple-dose protocol. Hum. Reprod. 20, 1200-1206.
6. Kolibianakis, E.M., Zikopoulos, K., Schiettecatte, J., et al., 2004. Profound LH suppression after GnRH antagonist administration is associated with a significantly higher ongoing pregnancy rate in IVF. Hum. Reprod. 19, 2490-2496.
7. Merviel, P., Antoine, J.M., Mathieu, E., et al., 2004. Luteinizing hormone concentrations after gonadotropin-releasing hormone antagonist administration do not influence pregnancy rates in in vitro fertilization-embryo transfer. Fertil. Steril. 82, 119-125.