Ultrasound-mediated delivery of echogenic immunoliposomes to porcine vascular smooth muscle cells in vivo

Journal of Liposome Research

Volumn 20, Issue 2, 2010, Pages 160-167

  Laing, Susan T ^a   Kim, Hyunggun ^a   Kopechek, Jonathan A ^b   Parikh, Devang ^c   Huang, Shaoling ^a   Klegerman, Melvin E ^a   Holland, Christy K ^b   McPherson, David D ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b 705 Engineering Research Center   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Targeted delivery; Ultrasound contrast agents

Indexed keywords

ACTIN ANTIBODY CALCEIN CONJUGATE; CALCEIN; ECHO CONTRAST MEDIUM; IMMUNOLIPOSOME; SMOOTH MUSCLE ACTIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG TARGETING; DRUG UPTAKE; FEMALE; FLUORESCENCE MICROSCOPY; HISTOLOGY; LIPOSOMAL DELIVERY; MINIPIG; NONHUMAN; PRIORITY JOURNAL; ULTRASOUND; VASCULAR SMOOTH MUSCLE;

ANIMALS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FEMALE; LIPOSOMES; MUSCLE, SMOOTH, VASCULAR; SWINE; SWINE, MINIATURE; ULTRASONICS;

EID: 77951637483     PISSN: 08982104     EISSN: 15322394     Source Type: Journal    
DOI: 10.3109/08982100903218918     Document Type: Article

References (42)

1. Alkan-Onyuksel, H., Murer, S. E., Lanza, G. M., Vonesh, M. J., Klegerman, M. E., McPherson, D. D. (1996). Development of inherently echogenic liposomes as an ultrasonic contrast agent. J Pharm Sci 85:486-490. (Pubitemid 26150981)
2. Bao, S., Trall, B. D., Miller, D. L. (1997). Transfection of a reporter plasmid into cultured cells by sonoporation in vitro. Ultrasound Med Biol 23:953-959. (Pubitemid 27349543)
3. Campbell, G. R., Campbell, J. H., Maderson, J. A., Horrigan, S., Rennick, R. E. (1988). Arterial smooth muscle: a multifunctional mesenchymal cell. Arch Pathol Lab Med 112:977-986.
4. Demos, S. M., Alkan-Onyuksel, H., Kane, B. J., Ramani, K., Nagaraj, A., Greene, R., et al. (1999). In-vivo targeting of acoustically refec-tive liposomes for intravascular ultrasonic enhancement. J Am Coll Cardiol 33:867-875.
5. Demos, S. M., Onyuksel, H., Gilbert, J., Roth, S. I., Kane, B., Jungblut, P., et al. (1997). In vitro targeting of antibody-conjugated echogenic liposomes for site-specifc ultrasonic image enhancement. J Pharm Sci 86:167-171.
6. Dzau, V. J., Braun-Dullaeus, R. C., Sedding, D. G. (2002). Vascular proliferation and atherosclerosis: new perspectives and therapeutic strategies. Nat Med 8:1249-1256.
7. Gavrieli, Y., Sherman, Y., Ben-Sasson, S. A. (1992). Identifcation of programmed cell death in situ via specifc labeling of nuclear DNA fragmentation. J Cell Biol 119:493-501.
8. Geng, Y. J., Libby, P. (2002). Progression of atheroma: a struggle between death and procreation. Arterioscler Tromb Vasc Biol 22:1370-1380.
9. Greenleaf, W. J., Bolander, M. E., Sarkar, G., Goldring, M. B., Greenleaf, J. F. (1998). Artifcial cavitation nuclei signifcantly enhance acoustically induced cell transfection. Ultrasound Med Biol 24:587-595. (Pubitemid 28252453)
10. Hamilton, A., Huang, S. L., Warnick, D., Stein, A., Rabbat, M., Madhav, T., et al. (2002). Left ventricular thrombus enhancement following intravenous injection of echogenic immunoliposomes: studies in a new experimental model. Circulation 105:2772-2778. (Pubitemid 34615150)
11. Hao, H., Gabbiani, G., Bochaton-Piallat, M. L. (2003). Arterial smooth muscle cell heterogeneity: implications for atherosclerosis and restenosis development. Arterioscler Tromb Vasc Biol 23:1510-1520. (Pubitemid 37108191)
12. Hedin, U., Roy, J., Tran, P. K. (2004). Control of smooth muscle cell proliferation in vascular disease. Curr Opin Lipidol 15:559-565. (Pubitemid 39336584)
13. Hillebrands, J. L., Rozing, J. (2003). Chronic transplant dysfunction and transplant arteriosclerosis: new insights into underlying mechanisms. (A contemporary review on the pathology of transplant arteriosclerosis.) Exp Rev Mol Med 2003:1-23.
14. Holland, C. K., Apfel, R. E. (1990). Tresholds for transient cavitation produced by pulsed ultrasound in a controlled nuclei environment. J Acoust Soc Am 88:2059-2069.
15. Horlitz, M., Sigwart, U., Niebauer, J. (2002). Fighting restenosis after coronary angioplasty: contemporary and future treatment options. Int J Cardiol 83:199-205. (Pubitemid 34564500)
16. Huang, S. L., Hamilton, A. J., Nagaraj, A., Tiukinhoy, S. D., Klegerman, M. E., McPherson, D. D., et al. (2001). Improving ultrasound refectivity and stability of echogenic liposomal dispersions for use as targeted ultrasound contrast agents. J Pharm Sci 90:1917-1926. (Pubitemid 33144437)
17. Huang, S. L., MacDonald, R. C. (2004). Acoustically active lipo-somes for drug encapsulation and ultrasound-triggered release. Biochim Biophy Acta 1665:134-141.
18. Huang, S. L., McPherson, D. D., MacDonald, E. C. (2008). A method to co-encapsulate gas and drugs in liposomes for ultrasound-controlled drug delivery. Ultrasound Med Biol 34:1272-1280.
19. Huang, S. L., McPherson, D. D., MacDonald, R. C. (2002a). Ultrasound in conjunction with an ultrasonic-refective transfection agent enhances gene delivery to cells [abstract]. J Am Coll Cardiol 39:228A.
20. Huang, S., Tiukinhoy, S., McPherson, D., MacDonald, R. (2002b). Combined use of ultrasound and acoustic cationic liposomes results in improved gene delivery into smooth muscle cells [abstract]. Molecular Ter 5:S9.
21. Kim, H. J., Greenleaf, J. F., Kinnick, R. R., Bronk, J. T., Bolander, M. E. (1996). Ultrasound-mediated transfection of mammalian cells. Hum Gene Ter 7:1339-1346.
22. Koch, S., Phol, P., Cobet, U., Rainov, N. G. (2000). Ultrasound enhancement of liposome-mediated cell transfection is caused by cavitation efects. Ultrasound Med Biol 26:897-903. (Pubitemid 30609606)
23. Kopechek, J. A., Abruzzo, T. M., Wang, B., Chrzanowski, S. M., Smith, D. A., Kee, P. H., et al. (2008). Ultrasound-mediated release of hydrophilic and lipophilic agents from echogenic liposomes. J Ultrasound Med 27:1597-1606.
24. Lanza, G. M., Alkan-Onyuksel, H., Klegerman, M. E., Vonesh, M. J., McPherson, D. D.(1997). Acoustically refective liposomes and methods to make and use the same. University of Illinois and Northwestern University. Issued March 18, 1997. Patent #5,612,057.
25. Lemarchand, P., Jones, M., Yamada, I., Crystal, R. G. (1993). In vivo gene transfer and expression in normal uninjured blood vessels using replication-defcient recombinant adenovirus vectors. Circ Res 72:1132-1138.
26. Maeda, Y., Ikeda, U., Ogasawara, Y., Urabe, M., Takizawa, T., Saito, T., et al. (1997). Gene transfer into vascular cells using adeno-asso-ciated virus (AAV) vectors. Cardiovas Res 35:514-521. (Pubitemid 27469413)
27. Miller, M. W., Miller, D. L., Brayman, A. A. (1996). A review of in vitro bioefects of inertial ultrasonic from a mechanistic perspective. Ultrasound Med Biol 22:1131-1154.
28. Newby, A. C. (2000). An overview of the vascular response to injury: a tribute to the late Russell Ross. Toxicol Lett 112:519-529.
29. Owens, G. K., Kumar, M. S., Wamhof, B. R. (2004). Molecular regulation of vascular smooth muscle cell diferentiation in development and disease. Physiol Rev 84:767-801. (Pubitemid 38823766)
30. Richter, M., Iwata, A., Nyhuis, J., Nitta, Y., Miller, A. D., Halbert, C. L., et al. (2000). Adeno-associated virus vector transduction of vascular smooth muscle cells in vivo. Physiol Genom 2:117-127.
31. Rome, J. J., Shayani, V., Flugelman, M. Y., Newman, K. D., Farb, A., Virmani, R., et al. (1994). Anatomic barriers infuence the distribution of in vivo gene transfer into the arterial wall. Modeling with microscopic tracer particles and verifcation with a recombinant adenoviral vector. Arterioscler Tromb 14:148-161.
32. Ross, R. (1986). Te pathogenesis of atherosclerosis: an update. NEJM 314:488-500.
33. Sarjeant, J. M., Rabinovich, M. (2002). Understanding and treating vein graft atherosclerosis. Cardiovasc Pathol 11:263-271. (Pubitemid 35292242)
34. Schwartz, S. M., Murry, C. E. (1998). Proliferation and the monoclonal origin of atherosclerotic lesions. Annu Rev Med 49: 437-460.
35. Sundarum, J., Mellein, B. R., Mitragotri, S. (2003). An experimental and theoretical analysis of ultrasound-induced permeabiliza-tion of cell membranes. Biophys J 84:3087-3101. (Pubitemid 36531757)
36. Tachibana, K., Tachibana, S. (2001). Te use of ultrasound for drug delivery. Echocardiography 18:323-328.
37. Tiukinhoy-Laing, S. D., Huang, S., Klegerman, M., Holland, C. K., McPherson, D. D. (2007). Ultrasound-facilitated thrombolysis using tissue-plasminogen activator-loaded echogenic lipo-somes. Tromb Res 119:777-784. (Pubitemid 46441423)
38. Tiukinhoy, S., Khan, A., Huang, S., Klegerman, M., MacDonald, R., McPherson, D. (2004). Novel echogenic drug-immunolipo-somes for drug delivery. Investig Radiol 39:104-110. (Pubitemid 38140541)
39. Tiukinhoy, S., Mahowald, M., Shively, V., Nagaraj, A., Kane, B., Klegerman, M., et al. (2000). Development of echogenic, plasmid-incorporated, tissue-targeted cationic liposomes that can be used for directed gene delivery. Investig Radiol 12:732-738. (Pubitemid 32039036)
40. Virmani, R., Farb, A. (1999). Pathology of in-stent restenosis. Curr Opin Lipidol 10:499-506. (Pubitemid 30064019)
41. Work, L. M., Nicklin, S. A., Brain, N. J., Dishart, K. L., Von Seggern, D. J., Hallek, M., et al. (2004). Development of efcient viral vectors selective for vascular smooth muscle cells. Molecular Ter 9:198-208. (Pubitemid 38256546)
42. Yao, A., Wang, D. H. (1995). Heterogeneity of adenovirus mediated gene transfer in cultured thoracic aorta and renal artery of rats. Hypertension 26:1046-1050.