Work disability remains a major problem in rheumatoid arthritis in the 2000s: Data from 32 countries in the QUEST-RA Study

Arthritis Research and Therapy

Volumn 12, Issue 2, 2010, Pages

  Sokka, Tuulikki ^a,b   Kautiainen, Hannu ^b   Pincus, Theodore ^c   Verstappen, Suzanne M M ^d   Aggarwal, Amita ^e   Alten, Rieke ^f   Andersone, Daina ^g   Badsha, Humeira ^h   Baecklund, Eva ⁱ   Belmonte, Miguel ^j   Craig Müller, Jürgen ^k   da Mota, Licia Maria Henrique ^l   Dimic, Alexander ^m   Fathi, Nihal A ⁿ   Ferraccioli, Gianfranco ^o   Fukuda, Wataru ^p   Géher, Pál ^q   Gogus, Feride ^r   Hajjaj Hassouni, Najia ^s   Hamoud, Hisham ^t   Haugeberg, Glenn ^u   Henrohn, Dan ⁱ   Horslev Petersen, Kim ^v   Ionescu, Ruxandra ^w   Karateew, Dmitry ^x   Kuuse, Reet ^y   Laurindo, Ieda Maria Magalhaes ^z   Lazovskis, Juris ^aa   Luukkainen, Reijo ^ab   Mofti, Ayman ^ac   Murphy, Eithne ^ad   Nakajima, Ayako ^ae   Oyoo, Omondi ^af   Pandya, Sapan C ^ag,ar   Pohl, Christof ^f   Predeteanu, Denisa ^w   Rexhepi, Mjellma ^ah   Rexhepi, Sylejman ^ah   Sharma, Banwari ^ai   Shono, Eisuke ^aj   Sibilia, Jean ^ak   Sierakowski, Stanislaw ^al   Skopouli, Fotini N ^am   Stropuviene, Sigita ^an   Toloza, Sergio ^ao   Valter, Ivo ^ap   Woolf, Anthony ^aq   Yamanaka, Hisashi ^ae   more..

^a JYVÄSKYLÄ CENTRAL HOSPITAL   (Finland)

^b Finland MedCare Ltd   (Finland)

^c NYU HOSPITAL FOR JOINT DISEASES   (United States)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^e SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

^f CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^g PAULS STRADINS CLINICAL UNIVERSITY HOSPITAL   (Latvia)

^h Dubai Bone and Joint Center   (United Arab Emirates)

ⁱ UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^j HOSPITAL GENERAL DE CASTELLÓN   (Spain)

^k CentraCare Clinic   (United States)

^l HOSPITAL UNIVERSITÁRIO DE BRASÍLIA   (Brazil)

^m Rheumatology Institut   (Serbia)

ⁿ ASSIUT UNIVERSITY   (Egypt)

^o CATHOLIC UNIVERSITY   (Italy)

^p KYOTO FIRST RED CROSS HOSPITAL   (Japan)

^q SEMMELWEIS UNIVERSITY   (Hungary)

^r GAZI UNIVERSITY   (Turkey)

^s MOHAMMED V UNIVERSITY   (Morocco)

^t AL AZHAR UNIVERSITY   (Egypt)

^u Department of Rheumatology   (Norway)

^v King Christian the Xth Hospital   (Denmark)

^w Spitalul Clinic Sf Maria   (Romania)

^x V A NASONOVA RESEARCH INSTITUTE OF RHEUMATOLOGY   (Russian Federation)

^y TARTU UNIVERSITY HOSPITAL   (Estonia)

^z UNIVERSITY OF SÃO PAULO   (Brazil)

^aa Riverside Professional Center   (Canada)

^ab SATAKUNTA CENTRAL HOSPITAL   (Finland)

^ac American Hospital Dubai   (United Arab Emirates)

^ad Stroke and Hypertension Unit   (Ireland)

^ae TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^af KENYATTA NATIONAL HOSPITAL   (Kenya)

^ag Rheumatic Disease Clinic   (India)

^ah UNIVERSITY CLINICAL CENTER OF KOSOVO   (Serbia)

^ai Jaipur Hospital   (India)

^aj Shono Rheumatism Clinic   (Japan)

^ak HÔPITAL DE HAUTEPIERRE   (France)

^al MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

^am Athens Euroclinic   (Greece)

^an VILNIUS UNIVERSITY   (Lithuania)

^ao Hospital Interzonal de Agudos San Juan Bautista   (Argentina)

^ap Center for Clinical and Basic Research   (Estonia)

^aq ROYAL CORNWALL HOSPITAL   (United Kingdom)

^ar Vedanta Institute of Medical Sciences   (India)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; DATA BASE; DISEASE ACTIVITY; ECONOMIC ASPECT; FEMALE; GROUPS BY AGE; HUMAN; MAJOR CLINICAL STUDY; MALE; RHEUMATOID ARTHRITIS; SCORING SYSTEM; SELF REPORT; WORK DISABILITY; CLINICAL TRIAL; DISABILITY; DISABLED PERSON; EMPLOYMENT; FACTUAL DATABASE; FATIGUE; HEALTH; HEALTH STATUS; HOSPITALIZATION; INSURANCE; MIDDLE AGED; MULTICENTER STUDY; OCCUPATIONAL MEDICINE; PAIN; PATHOPHYSIOLOGY; QUESTIONNAIRE; STATISTICS; WORK CAPACITY;

ARTHRITIS, RHEUMATOID; DATABASES, FACTUAL; DISABILITY EVALUATION; DISABLED PERSONS; EMPLOYMENT; FATIGUE; FEMALE; HEALTH STATUS; HUMANS; INSURANCE, DISABILITY; MALE; MIDDLE AGED; OCCUPATIONAL MEDICINE; PAIN; QUESTIONNAIRES; SEVERITY OF ILLNESS INDEX; WORK CAPACITY EVALUATION; WORLD HEALTH;

EID: 77951635465     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar2951     Document Type: Article

References (35)

1. Yelin E, Meenan R, Nevitt M, Epstein W. Work disability in rheumatoid arthritis: effects of disease, social, and work factors. Ann Intern Med 1980, 93:551-556.
2. Mäkisara GL, Mäkisara P. Prognosis of functional capacity and work capacity in rheumatoid arthritis. Clin Rheumatol 1982, 1:117-125. 10.1007/BF02275601, 6926808.
3. Pincus T, Callahan LF, Sale WG, Brooks AL, Payne LE, Vaughn WK. Severe functional declines, work disability, and increased mortality in seventy-five rheumatoid arthritis patients studied over nine years. Arthritis Rheum 1984, 27:864-872. 10.1002/art.1780270805, 6431998.
4. Sokka T, Krishnan E, Häkkinen A, Hannonen P. Functional disability in rheumatoid arthritis patients compared with a community population in Finland. Arthritis Rheum 2003, 48:59-63. 10.1002/art.10731, 12528104.
5. Sokka T. Work disability in early rheumatoid arthritis. Clin Exp Rheumatol 2003, 21:S71-S74.
6. Puolakka K, Kautiainen H, Möttönen T, Hannonen P, Korpela M, Hakala M, Järvinen P, Ahonen J, Forsberg S, Leirisalo-Repo M, . FIN-RACo Trial Group Early suppression of disease activity is essential for maintenance of work capacity in patients with recent-onset rheumatoid arthritis: five-year experience from the FIN-RACo trial. Arthritis Rheum 2005, 52:36-41. 10.1002/art.20716, 15641055, FIN-RACo Trial Group.
7. Verstappen SM, Jacobs JW, Hyrich KL. Effect of anti-tumor necrosis factor on work disability. J Rheumatol 2007, 34:2126-2128.
8. Yelin E, Trupin L, Katz P, Lubeck D, Rush S, Wanke L. Association between etanercept use and employment outcomes among patients with rheumatoid arthritis. Arthritis Rheum 2003, 48:3046-3054. 10.1002/art.11285, 14613265.
9. Smolen JS, Han C, Heijde D, Emery P, Bathon JM, Keystone E, Kalden JR, Schiff M, Bala M, Baker D, Han J, Maini RN, St Clair EW. Infliximab treatment maintains employability in patients with early rheumatoid arthritis. Arthritis Rheum 2006, 54:716-722. 10.1002/art.21661, 16508932.
10. Kimel M, Cifaldi M, Chen N, Revicki D. Adalimumab plus methotrexate improved SF-36 scores and reduced the effect of rheumatoid arthritis (RA) on work activity for patients with early RA. J Rheumatol 2008, 35:206-215.
11. Anis A, Zhang W, Emery P, Sun H, Singh A, Freundlich B, Sato R. The effect of etanercept on work productivity in patients with early active rheumatoid arthritis: results from the COMET study. Rheumatology (Oxford) 2009, 48:1283-1289. 10.1093/rheumatology/kep239, 19690125.
12. Kavanaugh A, Smolen JS, Emery P, Purcaru O, Keystone E, Richard L, Strand V, van Vollenhoven RF. Effect of certolizumab pegol with methotrexate on home and work place productivity and social activities in patients with active rheumatoid arthritis. Arthritis Rheum 2009, 61:1592-1600. 10.1002/art.24828, 19877104.
13. Wolfe F, Allaire S, Michaud K. The prevalence and incidence of work disability in rheumatoid arthritis, and the effect of anti-tumor necrosis factor on work disability. J Rheumatol 2007, 34:2211-2217.
14. Allaire S, Wolfe F, Niu J, Zhang Y, Zhang B, LaValley M. Evaluation of the effect of anti-tumor necrosis factor agent use on rheumatoid arthritis work disability: the jury is still out. Arthritis Rheum 2008, 59:1082-1089. 10.1002/art.23923, 18668597.
15. Laas K, Peltomaa R, Kautiainen H, Puolakka K, Leirisalo-Repo M. Pharmacoeconomic study of patients with chronic inflammatory joint disease before and during infliximab treatment. Ann Rheum Dis 2006, 65:924-928. 1798220, 16339293, 10.1136/ard.2005.041574.
16. Augustsson J, Neovius M, Cullinane-Carli C, Eksborg S, van Vollenhoven RF. Patients with rheumatoid arthritis treated with tumour necrosis factor antagonists increase their participation in the workforce: potential for significant long-term indirect cost gains (data from a population-based registry). Ann Rheum Dis 2010, 69:126-131. 10.1136/ard.2009.108035, 19470527.
17. Sokka T, Envalds M, Pincus T. Treatment of rheumatoid arthritis: a global perspective on the use of antirheumatic drugs. Mod Rheumatol 2008, 18:228-239. 2668379, 18437286, 10.1007/s10165-008-0056-x.
18. Eberhardt K. Very early intervention is crucial to improve work outcome in patients with rheumatoid arthritis. J Rheumatol 2009, 36:1104-1106. 10.3899/jrheum.090174, 19509088.
19. Chung CP, Sokka T, Arbogast P, Pincus T. Work disability in early rheumatoid arthritis: higher rates but better clinical status in Finland compared with the US. Ann Rheum Dis 2006, 65:1653-1657. 1798477, 16740683, 10.1136/ard.2005.048439.
20. Sokka T, Kautiainen H, Toloza S, Makinen H, Verstappen SMM, Hetland ML, Naranjo A, Baecklund E, Herborn G, Rau R, Cazzato M, Gossec L, Skakic V, Gogus F, Sierakowski S, Bresnihan B, Taylor P, McClinton C, Pincus T, . for the QUEST-RA Group QUEST-RA: quantitative clinical assessment of patients with rheumatoid arthritis seen in standard rheumatology care in 15 countries. Ann Rheum Dis 2007, 66:1491-1496. 10.1136/ard.2006.069252, 17412740, for the QUEST-RA Group.
21. Sokka T, Hetland ML, Makinen H, Kautiainen H, Horslev-Petersen K, Luukkainen RK, Combe B, Badsha H, Drosos AA, Devlin J, Ferraccioli G, Morelli A, Hoekstra M, Majdan M, Sadkiewicz S, Belmonte M, Holmqvist AC, Choy E, Burmester GR, Tunc R, Dimic A, Nedovic J, Stankovic A, Bergman M, Toloza S, Pincus T. Remission and rheumatoid arthritis: data on patients receiving usual care in twenty-four countries. Arthritis Rheum 2008, 58:2642-2651. 10.1002/art.23794, 18759292.
22. Pincus T, Brooks RH, Callahan LF. A proposed standard protocol to evaluate rheumatoid arthritis (SPERA) that includes measures of inflammatory activity, joint damage, and longterm outcomes. J Rheumatol 1999, 26:473-480.
23. Fries JF, Spitz P, Kraines RG, Holman HR. Measurement of patient outcome in arthritis. Arthritis Rheum 1980, 23:137-145. 10.1002/art.1780230202, 7362664.
24. Pincus T, Swearingen C, Wolfe F. Toward a multidimensional health assessment questionnaire (MDHAQ): assessment of advanced activities of daily living and psychological status in the patient friendly health assessment questionnaire format. Arthritis Rheum 1999, 42:2220-2230. 10.1002/1529-0131(199910)42:10<2220::AID-ANR26>3.0.CO;2-5, 10524697.
25. International Monetary Fund: World Economic Outlook Databases. , http://www.imf.org/external/ns/cs.aspx?id=28
26. Prevoo MLL, van't Hof MA, Kuper HH, van Leeuwen MA, Putte LBA, van Riel PLCM. Modified disease activity scores that include twenty-eight-joint counts: Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 1995, 38:44-48. 10.1002/art.1780380107, 7818570.
27. Sokka T, Kautiainen H, Pincus T, Toloza S, da Rocha Castelar Pinheiro G, Lazovskis J, Hetland ML, Peets T, Immonen K, Maillefert JF, Drosos AA, Alten R, Pohl C, Rojkovich B, Bresnihan B, Minnock P, Cazzato M, Bombardieri S, Rexhepi S, Rexhepi M, Andersone D, Stropuviene S, Huisman M, Sierakowski S, Karateev D, Skakic V, Baecklund E, Henrohn D, Gogus F, Badsha H, et al. Disparities in rheumatoid arthritis disease activity according to gross domestic product in 25 countries in the QUEST-RA database. Ann Rheum Dis 2009, 68:1666-1672. 2756954, 19643759, 10.1136/ard.2009.109983.
28. Möttönen T, Hannonen P, Korpela M, Nissilä M, Kautiainen H, Ilonen J, Laasonen L, Kaipiainen-Seppänen O, Franzen P, Helve T, Koski J, Gripenberg-Gahmberg M, Myllykangas-Luosujärvi R, Leirisalo-Repo M. Delay to institution of therapy and induction of remission using single-drug or combination-disease-modifying antirheumatic drug therapy in early rheumatoid arthritis. Arthritis Rheum 2002, 46:894-898. 10.1002/art.10135, 11953964.
29. Engel GL. The need for a new medical model: a challenge for biomedicine. Science 1977, 196:129-136. 10.1126/science.847460, 847460.
30. Verstappen SM, Boonen A, Verkleij H, Bijlsma JW, Buskens E, Jacobs JW. Productivity costs among patients with rheumatoid arthritis: the influence of methods and sources to value loss of productivity. Ann Rheum Dis 2005, 64:1754-1760. 1755315, 15860510, 10.1136/ard.2004.033977.
31. Sokka T, Pincus T. Markers for work disability in rheumatoid arthritis. J Rheumatol 2001, 28:1718-1722.
32. Odegard S, Finset A, Kvien TK, Mowinckel P, Uhlig T. Work disability in rheumatoid arthritis is predicted by physical and psychological health status: a 7-year study from the Oslo RA register. Scand J Rheumatol 2005, 34:441-447. 10.1080/03009740510018633, 16393765.
33. Reisine ST, Grady KE, Goodenow C, Fifield J. Work disability among women with rheumatoid arthritis: the relative importance of disease, social, work, and family factors. Arthritis Rheum 1989, 32:538-543. 10.1002/anr.1780320505, 2719729.
34. Callahan LF, Bloch DA, Pincus T. Identification of work disability in rheumatoid arthritis: Physical, radiographic and laboratory variables do not add explanatory power to demographic and functional variables. J Clin Epidemiol 1992, 45:127-138. 10.1016/0895-4356(92)90005-8, 1573429.
35. Puolakka K, Kautiainen H, Mottonen T, Hannonen P, Korpela M, Hakala M, Viikari-Juntura E, Solovieva S, Arkela-Kautiainen M, Leirisalo-Repo M. A mismatch between self-reported physical work load and the HAQ: early identification of rheumatoid arthritis patients at risk for loss of work productivity. Clin Exp Rheumatol 2009, 27:422-429.