Induction of chronic renal allograft dysfunction in a rat model with complete and exclusive MHC incompatibility

Transplant Immunology

Volumn 22, Issue 3-4, 2010, Pages 137-143

  Poehnert, Daniel ^a   Broecker, Verena ^a   Mengel, Michael ^b   Nashan, Bjoern ^c   Koch, Martina ^c  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF ALBERTA   (Canada)

^c UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Chronic rejection; Donor specific antibodies; Kidney transplantation; MHC; Rat model

Indexed keywords

COMPLEMENT; GLOMERULUS BASEMENT MEMBRANE ANTIBODY; HLA ANTIBODY; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ALBUMINURIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY DETECTION; ARTICLE; CELLULAR IMMUNITY; CHRONIC ALLOGRAFT NEPHROPATHY; CONGENIC STRAIN; CONTROLLED STUDY; GLOMERULOPATHY; GRAFT RECIPIENT; GRAFT SURVIVAL; HISTOINCOMPATIBILITY; HISTOPATHOLOGY; HUMORAL IMMUNITY; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY DYSFUNCTION; KIDNEY FAILURE; KIDNEY FUNCTION; KIDNEY GRAFT; KIDNEY TRANSPLANTATION; LEWIS RAT; LYMPHOCYTIC INFILTRATION; MACROPHAGE; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; RAT;

ALBUMINURIA; ANIMALS; CELL MOVEMENT; CELLS, CULTURED; CHRONIC DISEASE; FIBROSIS; GLOMERULONEPHRITIS, MEMBRANOUS; GRAFT REJECTION; HISTOCOMPATIBILITY; HISTOCOMPATIBILITY ANTIGENS; ISOANTIBODIES; KIDNEY FAILURE; KIDNEY TRANSPLANTATION; KIDNEY TUBULES; MACROPHAGES; MALE; PRIMARY GRAFT DYSFUNCTION; RATS; RATS, INBRED LEW; T-LYMPHOCYTES;

EID: 77951633959     PISSN: 09663274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trim.2009.09.007     Document Type: Article

References (29)

1. de Bruijne M.H., et al. Predicting kidney graft failure using time-dependent renal function covariates. J Clin Epidemiol 2003, 56(5):448-455.
2. Gourishankar, S., et al., Serum cystatin C performs similarly to traditional markers of kidney function in the evaluation of donor kidney function prior to and following unilateral nephrectomy. Nephrol Dial Transplant, 2008. Electronic publication ahead of print.
3. Joosten S.A., et al. The pathobiology of chronic allograft nephropathy: immune-mediated damage and accelerated aging. Kidney Int 2004, 65(5):1556-1559.
4. Chapman J.R. Longitudinal analysis of chronic allograft nephropathy: clinicopathologic correlations. Kidney Int Suppl 2005, 99:S108-S112.
5. Solez K., et al. Banff '05 Meeting Report: differential diagnosis of chronic allograft injury and elimination of chronic allograft nephropathy ('CAN'). Am J Transplant 2007, 7(3):518-526.
6. Sijpkens Y.W., et al. Sharing cross-reactive groups of MHC class I improves long-term graft survival. Kidney Int 1999, 56(5):1920-1927.
7. Cardarelli F., et al. Prevalence and significance of anti-HLA and donor-specific antibodies long-term after renal transplantation. Transpl Int 2005, 18(5):532-540.
8. Opelz G., Dohler B. Effect of human leukocyte antigen compatibility on kidney graft survival: comparative analysis of two decades. Transplantation 2007, 84(2):137-143.
9. Opelz G. Impact of HLA compatibility on survival of kidney transplants from unrelated live donors. Transplantation 1997, 64(10):1473-1475.
10. Susal C., Opelz G. Kidney graft failure and presensitization against HLA class I and class II antigens. Transplantation 2002, 73(8):1269-1273.
11. Li X., Li X., et al. Poor graft outcome in recipients with de novo donor-specific anti-HLA antibodies after living related kidney transplantation. Transpl Int 2008.
12. Wolters H.H., et al. Living donor kidney transplantation: impact of differentiated immunosuppressive regimen. Transplant Proc 2005, 37(3):1616-1617.
13. Pratschke J., et al. Potent early immune response after kidney transplantation in patients of the European senior transplant program. Transplantation 2009, 87(7):992-1000.
14. Koch M., et al. Adoptive transfer of primed CD4+ T-lymphocytes induces pattern of chronic allograft nephropathy in a nude rat model. Transplantation 2005, 79(7):753-761.
15. Solez K., et al. Banff 07 classification of renal allograft pathology: updates and future directions. Am J Transplant 2008, 8(4):753-760.
16. Hunig T., et al. A monoclonal antibody to a constant determinant of the rat T cell antigen receptor that induces T cell activation. Differential reactivity with subsets of immature and mature T lymphocytes. J Exp Med 1989, 169(1):73-86.
17. Demirci G., Nashan B., Pichlmayr R. Fibrosis in chronic rejection of human liver allografts: expression patterns of transforming growth factor-TGFbeta1 and TGF-beta3. Transplantation 1996, 62(12):1776-1783.
18. Minami K., et al. C4d deposition and clearance in cardiac transplants correlates with alloantibody levels and rejection in rats. Am J Transplant 2006, 6(5 Pt 1):923-932.
19. Joosten S.A., et al. Antibody response against perlecan and collagen types IV and VI in chronic renal allograft rejection in the rat. Am J Pathol 2002, 160(4):1301-1310.
20. Lagiewska B., et al. Hemodynamic and metabolic disturbances observed in brain-dead organ donors. Transplant Proc 1996, 28(1):165-166.
21. Nankivell B.J., et al. Calcineurin inhibitor nephrotoxicity: longitudinal assessment by protocol histology. Transplantation 2004, 78(4):557-565.
22. Yilmaz S., Paavonen T., Hayry P. Chronic rejection of rat renal allografts. II. The impact of prolonged ischemia time on transplant histology. Transplantation 1992, 53(4):823-827.
23. Sanchez-Fructuoso A.I., et al. Does renal mass exert an independent effect on the determinants of antigen-dependent injury?. Transplantation 2001, 71(3):381-386.
24. Sola R., et al. Glomerular hyperfiltration, intrarenal hemodynamics, and chronic allograft nephropathy: physiopathology of chronic allograft nephropathy. Transplant Proc 2002, 34(1):340-342.
25. Nickeleit V., Andreoni K. The classification and treatment of antibody-mediated renal allograft injury: where do we stand?. Kidney Int 2007, 71(1):7-11.
26. Szebeni J., et al. Animal models of complement-mediated hypersensitivity reactions to liposomes and other lipid-based nanoparticles. J Liposome Res 2007, 17(2):107-117.
27. Feucht H.E., et al. Capillary deposition of C4d complement fragment and early renal graft loss. Kidney Int 1993, 43(6):1333-1338.
28. Girlanda R., et al. Monocyte infiltration and kidney allograft dysfunction during acute rejection. Am J Transplant 2008, 8(3):600-607.
29. Shimizu A., et al. Intragraft events preceding chronic renal allograft rejection in a modified tolerance protocol. Kidney Int 2000, 58(6):2546-2558.