Subchondral bone attrition may be a reflection of compartment-specific mechanical load: The MOST Study

Annals of the Rheumatic Diseases

Volumn 69, Issue 5, 2010, Pages 841-844

  Neogi, Tuhina ^a   Nevitt, Michael ^b   Niu, Jingbo ^a   Sharma, Leena ^c   Roemer, Frank ^d   Guermazi, Ali ^a   Lewis, Cora E ^e   Torner, James ^f   Javaid, Kassim ^b   Felson, David ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

^d KLINIKUM AUGSBURG   (Germany)

^e UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^f UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BODY IMAGE; BODY MASS; BONE DENSITY; CARTILAGE; CLINICAL TRIAL; COHORT ANALYSIS; FEMALE; HIGH RISK BEHAVIOR; HUMAN; KNEE; KNEE OSTEOARTHRITIS; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NUCLEAR MAGNETIC RESONANCE; OSTEOARTHRITIS; PRIORITY JOURNAL; PROSPECTIVE STUDY; SUBCHONDRAL BONE ATTRITION; VARUS KNEE; WHOLE BODY MRI;

AGED; BONE DENSITY; BONE RESORPTION; FEMALE; HUMANS; KNEE JOINT; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; OSTEOARTHRITIS, KNEE; STRESS, MECHANICAL; WEIGHT-BEARING;

EID: 77951613943     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/ard.2009.110114     Document Type: Article

References (35)

1. Bullough PG. Osteoarthritis and related disorders: pathology. In: Klippel JH, Dieppe P, eds. Rheumatology. 2nd ed. London: Mosby, 1998:1-8.
2. Anderson-MacKenzie JM, Quasnichka HL, Starr RL, et al. Fundamental subchondral bone changes in spontaneous knee osteoarthritis. Int J Biochem Cell Biol 2005;37:224-236
3. Hayami T, Pickarski M, Zhuo Y, et al. Characterization of articular cartilage and subchondral bone changes in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis. Bone 2006;38:234-243 (Pubitemid 43165790)
4. Reichenbach S, Guermazi A, Niu J, et al. Prevalence of bone attrition on knee radiographs and MRI in a community-based cohort. Osteoarthr Cartil 2008;16:1005-1010
5. Felson DT, Chaisson CE, Hill CL, et al. The association of bone marrow lesions with pain in knee osteoarthritis. Ann Intern Med 2001;134:541-549 (Pubitemid 32245315)
6. Kornaat PR, Kloppenburg M, Sharma R, et al. Bone marrow edema-like lesions change in volume in the majority of patients with osteoarthritis; associations with clinical features. Eur Radiol 2007;17:3073-3078 (Pubitemid 350142331)
7. Wluka AE, Hanna F, Davies-Tuck M, et al. Bone marrow lesions predict increase in knee cartilage defects and loss of cartilage volume in middle-aged women without knee pain over 2 years. Ann Rheum Dis 2009;68:850-855
8. Shi J, Reichenbach SE, Howe JD. Small-kernel superresolution methods for microscanning imaging systems. Appl Opt 2006;45:1203-1214
9. Torres L, Dunlop DD, Peterfy C, et al. The relationship between specific tissue lesions and pain severity in persons with knee osteoarthritis. Osteoarthr Cartil 2006;14:1033-1040 (Pubitemid 44321374)
10. Hernández-Molina G, Neogi T, Hunter DJ, et al. The association of bone attrition with knee pain and other MRI features of osteoarthritis. Ann Rheum Dis 2008;67:43-47
11. Neogi T, Felson D, Niu J, et al. Cartilage loss occurs in the same subregions as subchondral bone attrition: a within-knee subregion-matched approach from the Multicenter Osteoarthritis Study. Arthritis Rheum 2009;61:1539-1544
12. Sharma L, Song J, Felson DT, et al. The role of knee alignment in disease progression and functional decline in knee osteoarthritis. JAMA 2001;286:188-195 (Pubitemid 32640850)
13. Hunter DJ, Zhang Y, Niu J, et al. Structural factors associated with malalignment in knee osteoarthritis: the Boston osteoarthritis knee study. J Rheumatol 2005;32:2192-2199 (Pubitemid 41587867)
14. Burr DB. The importance of subchondral bone in the progression of osteoarthritis. J Rheumatol Suppl 2004;70:77-80. (Pubitemid 38524574)
15. Carbone LD, Nevitt MC, Wildy K, et al. The relationship of antiresorptive drug use to structural findings and symptoms of knee osteoarthritis. Arthritis Rheum 2004;50:3516-3525 (Pubitemid 39488676)
16. Felson DT, Niu J, Guermazi A, et al. Correlation of the development of knee pain with enlarging bone marrow lesions on magnetic resonance imaging. Arthritis Rheum 2007;56:2986-2992 (Pubitemid 47502745)
17. Peterfy CG, Guermazi A, Zaim S, et al. Whole-Organ Magnetic Resonance Imaging Score (WORMS) of the knee in osteoarthritis. Osteoarthr Cartil 2004;12:177-190 (Pubitemid 38248067)
18. Englund M, Guermazi A, Roemer FW, et al. Meniscal tear in knees without surgery and the development of radiographic osteoarthritis among middle-aged and elderly persons: The Multicenter Osteoarthritis Study. Arthritis Rheum 2009;60:831-839
19. Zhang Y, Hannan MT, Chaisson CE, et al. Bone mineral density and risk of incident and progressive radiographic knee osteoarthritis in women: the Framingham Study. J Rheumatol 2000;27:1032-1037 (Pubitemid 30389764)
20. Buckland-Wright JC, Wolfe F, Ward RJ, et al. Substantial superiority of semiflexed (MTP) views in knee osteoarthritis: a comparative radiographic study, without fluoroscopy, of standing extended, semiflexed (MTP), and schuss views. J Rheumatol 1999;26:2664-2674
21. Felson DT, McAlindon TE, Anderson JJ, et al. Defining radiographic osteoarthritis for the whole knee. Osteoarthr Cartil 1997;5:241-250 (Pubitemid 27315903)
22. Altman RD, Hochberg M, Murphy WA Jr, et al. Atlas of individual radiographic features in osteoarthritis. Osteoarthr Cartil 1995;3(Suppl A):3-70.
23. Kellgren JH, Lawrence JS. Radiological assessment of osteo-arthrosis. Ann Rheum Dis 1957;16:494-502.
24. Carlson CS, Loeser RF, Jayo MJ, et al. Osteoarthritis in cynomolgus macaques: a primate model of naturally occurring disease. J Orthop Res 1994;12:331-339
25. Radin EL, Paul IL, Rose RM. Role of mechanical factors in pathogenesis of primary osteoarthritis. Lancet 1972;1:519-522
26. Radin EL, Martin RB, Burr DB, et al. Effects of mechanical loading on the tissues of the rabbit knee. J Orthop Res 1984;2:221-234 (Pubitemid 15220006)
27. Radin EL, Rose RM. Role of subchondral bone in the initiation and progression of cartilage damage. Clin Orthop Relat Res 1986;213:34-40.
28. Wu DD, Burr DB, Boyd RD, et al. Bone and cartilage changes following experimental varus or valgus tibial angulation. J Orthop Res 1990;8:572-585
29. Felson DT, McLaughlin S, Goggins J, et al. Bone marrow edema and its relation to progression of knee osteoarthritis. Ann Intern Med 2003;139:330-336
30. Ding M, Odgaard A, Hvid I. Changes in the three-dimensional microstructure of human tibial cancellous bone in early osteoarthritis. J Bone Joint Surg Br 2003;85:906-912 (Pubitemid 36986859)
31. Grynpas MD, Alpert B, Katz I, et al. Subchondral bone in osteoarthritis. Calcif Tissue Int 1991;49:20-26
32. Li B, Aspden RM. Mechanical and material properties of the subchondral bone plate from the femoral head of patients with osteoarthritis or osteoporosis. Ann Rheum Dis 1997;56:247-254 (Pubitemid 27239581)
33. Li B, Aspden RM. Composition and mechanical properties of cancellous bone from the femoral head of patients with osteoporosis or osteoarthritis. J Bone Miner Res 1997;12:641-651 (Pubitemid 27155224)
34. Dedrick DK, Goldstein SA, Brandt KD, et al. A longitudinal study of subchondral plate and trabecular bone in cruciate-deficient dogs with osteoarthritis followed up for 54 months. Arthritis Rheum 1993;36:1460-1467
35. Dieppe PA, Reichenbach S, Williams S, et al. Assessing bone loss on radiographs of the knee in osteoarthritis: a cross-sectional study. Arthritis Rheum 2005;52:3536-3541 (Pubitemid 41612221)