Evaluation of the protein C global assay during normal pregnancy and after assisted reproduction

Obstetrics and Gynecology

Volumn 115, Issue 5, 2010, Pages 969-974

  Younis, Johnny S ^a   Shukha, Mervatte ^b   Ben Ami, Moshe ^b   Izhaki, Ido ^b   Blumenfeld, Zeev ^b   Brenner, Benjamin ^b   Sarig, Galit ^b  

^a Poriya Hospital   (Israel)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN C;

ADULT; ARTICLE; ASSAY; CESAREAN SECTION; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; FEMALE INFERTILITY; FERTILIZATION IN VITRO; HUMAN; HYPERCOAGULABILITY; INFERTILITY THERAPY; INTRACYTOPLASMIC SPERM INJECTION; MAJOR CLINICAL STUDY; PREGNANCY; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN DETERMINATION; THROMBOPHILIA; VAGINAL DELIVERY;

ADULT; FEMALE; HUMANS; INFERTILITY, FEMALE; PARTIAL THROMBOPLASTIN TIME; PREGNANCY; PREGNANCY TRIMESTER, FIRST; PREGNANCY TRIMESTER, SECOND; PROSPECTIVE STUDIES; PROTEIN C; REPRODUCTIVE TECHNIQUES, ASSISTED;

EID: 77951609774     PISSN: 00297844     EISSN: None     Source Type: Journal    
DOI: 10.1097/AOG.0b013e3181db67f3     Document Type: Article

References (28)

1. Brenner B. Haemostatic changes in pregnancy. Thromb Res 2004;114:409-414
2. De Stefano V, Finazzi G, Mannucci PM. Inherited thrombo-philia: pathogenesis, clinical syndromes, and management. Blood 1996;87:3531-3544
3. Lane DA, Mannucci PM, Bauer KA, Bertina RM, Bochkov NP, Boulyjenkov V, et al. Inherited thrombophilia: Part 1. Thromb Haemost 1996;76:651-662
4. Seligsohn U, Lubetsky A. Genetic susceptibility to venous thrombosis. N Engl J Med 2001;344:1222-1231
5. Brenner B, Kupferminc MJ. Inherited thrombophilia and poor pregnancy outcome. Best Practice Research Clinic. Obstet Gynaecol 2003;17:427-439
6. Robert A, Eschwege V, Hameg H, Drouet L, Aillaud MF. Anticoagulant response to Agkistrodon contortrix venom (ACV test): a new global test to screen for defects in the anticoagulant protein C Pathway. Thromb Haemost 1996;75: 562-566
7. Dati F, Hafner G, Erbes H, Prellwitz W, Kraus M, Niemann F, Noah M, Wagner C. ProC Global: the first functional screening assay for the complete protein C pathway. Clin Chem 1997;43:1719-1723
8. Tripodi A, Akhavan S, Asti D, Faioni EM, Mannucci PM. Laboratory screening of thrombophilia. Evaluation of the diagnostic efficacy of a global test to detect congenital deficiencies of the protein C anticoagulation pathway. Blood Coag Fibrinol 1998;9:485-489
9. Grand'Maison A, Bates SM, Johnston M, McRae S, Ginsberg JS. "ProC Global": a functional screening test that predicts recurrent venous thromboembolism. Thromb Haemost 2005; 93:600-604
10. Toulon P, Halbmeyer WM, Hafner G, Schmitt Y, Randgard B, Odpadlik M, et al. Screening for abnormalities of the Protein C anticoagulant pathway using the ProC Global assay. Results of European multicenter evaluation. Blood Coag Fibrinol 2000; 11:447-454
11. Koivurova S, Hartikainen A, Karinen L, Gissler M, Hemminki E, Martikainen H, et al. The course of pregnancy and delivery and the use of maternal healthcare services after standard IVF in Northern Finland 1990-1995. Hum Reprod 2002;17: 2897-2903
12. Ombelet W, Martens G, De Sutter P, Gerris J, Bosmans E, Ruyssinck G, et al. Perinatal outcome of 12,021 singleton and 3108 twin births after non-IVF-assisted reproduction: a cohort study. Hum Reprod 2006;21:1025-1032
13. Luke B, Keith LG. The contribution of singletons, twins and triplets to low birth weight, infant mortality and handicap in the United States. J Reprod Med 1992;37:661-666
14. Andersen N, Wohlfahrt J, Christens P, Olsen J, Melbye M. Maternal age and fetal loss: population based register linkage study. BMJ 2000;320:1708-1712
15. Helmerhost FM, Perquin DA, Donker D, Keirse MJ. Perinatal outcome of singletons and twins after assisted conception: a systematic review of controlled studies. BMJ 2004;328:261-265
16. Jackson RA, Gibson KA, Wu YW, Croughan MS. Perinatal outcomes in singletons following in vitro fertilization: a meta-analysis. Obstet Gynecol 2004;103:551-563
17. McDonald SD, Murphy K, Beyene J, Ohlsson A. Perinatal outcomes of singleton pregnancies achieved by in vitro fertilization: a systematic review and meta-analysis. Obstet Gynecol 2005;27:449-459
18. Younis JS, Radin O, Mirsky N, Izhaki I, Majara T, Bar-ami S, et al. First polar body and nucleolar precursor body morphology is related to the ovarian reserve of infertile women. Reprod BioMed Online 2008;16:851-858
19. Younis JS, Jadaon J, Izhaki I, Haddad S, Radin O, Bar-Ami S, et al. A Simple multivariate score could predict ovarian reserve, as well as pregnancy rate, in infertile women. Fertil Steril 2009 Apr 13, Epub ahead of print.
20. Dhont M, De Sutter P, Ruyssinck G, Martens G, Bekaert A. Perinatal outcome of pregnancies after assisted reproduction: a case-control study. Am J Obstet Gynecol 1999;181:688-695
21. Blickstein I. Does assisted reproduction technology, per se, increase the risk of preterm birth? Br J Obstet Gynaecol 2006;113S:68-71.
22. Sarig G, Aberbach I, Schliamser L, Blumenfeld Z, Brenner B. Evaluation of ProC Global assay in women with history of venous thromboembolism on hormonal therapy. Thromb Haemost 2006;96:578-583
23. Eichinger S, Hron G, Hirshl M, Bialonczyk C, Minar E, Kollars M, et al. Prediction of recurrent venous thromboem-bolism by measuring ProC Global. Throm Haemost 2007;98: 1232-1236
24. Toulon P, Perez P, Rapp J, Adda R. An abnormal ProC Global test result is associated with an increased risk of venous thromboembolism independent of test sensitivity for protein C pathway abnormalities. Thromb Haemost 2007;98:288-333
25. Heilmann L, von Tempelhoff GF, Pollow K. Pro C Global assay in the evaluation of women with history of severe pre-eclampsia or HELLP syndrome. Clin Appl Thrmb Hemost 2002;8:319-324
26. Sarig G, Lanir N, Hoffman R, et al. Protein C global assay in the evaluation of women with idiopathic pregnancy loss. Thromb Haemost 2002;87:32-36
27. Bremme K. Haemostasis in normal pregnancy. In: Women's issues in thrombosis and Hemostasis. Brenner B, Marder VG, Conard J, editors, London (UK): Martin Dunitz Ltd; 2002. p. 151-165
28. Allen VM, Wilson RD, Cheung A. Pregnancy outcomes after assisted reproductive technology. J Obstet Gynaecol Can 2006;28:220-250