A robust method to coat allograft bone with a drug-releasing polymer shell

Biomedical Sciences Instrumentation

Volumn 46, Issue , 2010, Pages

  Davidoff, Sherry N ^a   Call, Brent P ^a   Hogrebe, Paul C ^b   Grainger, David W ^a,b   Brooks, Amanda E ^a  

^a UNIVERSITY OF UTAH   (United States)

^b University of Utah   (United States)

Author keywords

Allograft bone; Controlled drug delivery system; Dip coating; Drug loading; Methanol flocculation; Orthopedic infection; Phase separation; Polycaprolactone; Tobramycin; Vacuum drying

Indexed keywords

CONTROLLED DRUG DELIVERY SYSTEMS; DIP COATING; DRUG LOADING; TOBRAMYCIN; VACUUM DRYING;

ANTIBIOTICS; BONE; DEWATERING; DRUG THERAPY; DRYING; FLOCCULATION; METHANOL; PHASE MODULATION; PHASE SEPARATION; PLASTIC COATINGS; POLYCAPROLACTONE; POLYMERS; VACUUM;

CONTROLLED DRUG DELIVERY;

POLYCAPROLACTONE; TOBRAMYCIN;

ARTICLE; BONE GRAFT; CONTROLLED RELEASE FORMULATION; DRUG COATING; DRUG RELEASE; MATERIAL COATING; SCANNING ELECTRON MICROSCOPE; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY;

EID: 77951594768     PISSN: 00678856     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Kalorama Information Market Intelligence Report, Orthopedic Biomaterials: World Market, September 2007.
2. Gallazzi et al. "Early Radiological Diagnosis and Differential Diagnosis of Infection in Orthopaedic Surgery" in Infection and Local Treatment in Orthopedic Surgery, Springer 2007.
3. C. B. Landersdorfer, J. B. Bulitta, M. Kinzig, U. Holzgrabe, and F. Sorgel, "Penetration of antibacterials into bone: pharmacokinetic, pharmacodynamic and bioanalytical considerations," Clin Pharmacokinet, vol. 48, pp. 89-124, 2009.
4. Pendegrass, C.J., A.E. Goodship, and G.W. Blunn, Development of a soft tissue seal around bone-anchored transcutaneous amputation prostheses. Biomaterials, 2006. 27(23): p. 4183-4191
5. Antoci, V., Jr., et al., The inhibition of Staphylococcus epidermidis biofilm formation by vancomycin-modified titanium alloy and implications for the treatment of periprosthetic infection. Biomaterials, 2008. 29(35): p. 4684-4690
6. A. Aneja, et al., "Analysis of tobramycin release from beta tricalcium phosphate drug delivery system.," Biomed Sci Instrum, vol. 44, pp. 88-93, 2008.
7. M. E. J. Erling B. Pedersen, Michael B. Pedersen , Charlotte Siggaard , Tina B. Sørensen , Gert Mulvad , Jens C. Hansen, Anne M. Torstensen , Ole Aagaard , Henning Skjoldborg, "Plasma amino acids in Greenlanders and Danes. influence of seasons, residence, ethnicity, and diet," American Journal of Human Biology, vol. 18, pp. 99-111.