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Volumn 38, Issue 11, 2010, Pages 3595-3604

Down syndrome fibroblasts and mouse Prep1-overexpressing cells display increased sensitivity to genotoxic stress

Author keywords

[No Author keywords available]

Indexed keywords

HOMEODOMAIN PROTEIN; LUCIFERASE; PROTEIN BCL XL; PROTEIN P53; PROTEIN PREP1; RNA; UNCLASSIFIED DRUG;

EID: 77951586942     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkq019     Document Type: Article
Times cited : (23)

References (25)
  • 1
    • 34548530884 scopus 로고    scopus 로고
    • Comprehensive analysis of animal TALE homeobox genes: new conserved motifs and cases of accelerated evolution
    • Mukherjee,K. and Bürglin,T.R. (2007) Comprehensive analysis of animal TALE homeobox genes: new conserved motifs and cases of accelerated evolution. J. Mol. Evol., 65, 137-153.
    • (2007) J. Mol. Evol. , vol.65 , pp. 137-153
    • Mukherjee, K.1    Bürglin, T.R.2
  • 5
    • 61749103631 scopus 로고    scopus 로고
    • Prep1 directly regulates the intrinsic apoptotic pathway by controlling Bcl-XL levels
    • Micali,N., Ferrai,C., Fernandez-Diaz,L.C., Blasi,F. and Crippa,M.P. (2009) Prep1 directly regulates the intrinsic apoptotic pathway by controlling Bcl-XL levels. Mol. Cell. Biol., 29, 1143-1151.
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 1143-1151
    • Micali, N.1    Ferrai, C.2    Fernandez-Diaz, L.C.3    Blasi, F.4    Crippa, M.P.5
  • 6
    • 0034284637 scopus 로고    scopus 로고
    • Mitochondria as the central control point of apoptosis
    • Desagher,S. and Martinou,J.C. (2000) Mitochondria as the central control point of apoptosis. Trends Cell. Biol., 10, 369-377.
    • (2000) Trends Cell. Biol. , vol.10 , pp. 369-377
    • Desagher, S.1    Martinou, J.C.2
  • 7
    • 0037213368 scopus 로고    scopus 로고
    • The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions
    • Borner,C. (2003) The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions. Mol. Immunol., 39, 615-647.
    • (2003) Mol. Immunol. , vol.39 , pp. 615-647
    • Borner, C.1
  • 9
    • 14644396515 scopus 로고    scopus 로고
    • ets-2 promotes the activation of a mitochondrial death pathway in Down's syndrome neurons
    • Helguera,P., Pelsman,A., Pigino,G., Wolvetang,E., Head,E. and Busciglio,J. (2005) ets-2 promotes the activation of a mitochondrial death pathway in Down's syndrome neurons. J. Neurosci., 25, 2295-2303.
    • (2005) J. Neurosci. , vol.25 , pp. 2295-2303
    • Helguera, P.1    Pelsman, A.2    Pigino, G.3    Wolvetang, E.4    Head, E.5    Busciglio, J.6
  • 12
    • 0033593483 scopus 로고    scopus 로고
    • Apoptosis-associated proteins p53 and APO-1/Fas (CD95) in brains of adult patients with Down syndrome
    • Seidl,R., Fang-Kircher,S., Bidmon,B., Cairns,N. and Lubec,G. (1999) Apoptosis-associated proteins p53 and APO-1/Fas (CD95) in brains of adult patients with Down syndrome. Neurosci. Lett., 260, 9-12.
    • (1999) Neurosci. Lett. , vol.260 , pp. 9-12
    • Seidl, R.1    Fang-Kircher, S.2    Bidmon, B.3    Cairns, N.4    Lubec, G.5
  • 14
    • 0032518418 scopus 로고    scopus 로고
    • PKNOX1, a gene encoding PREP1, a new regulator of Pbx activity, maps on human chromosome 21q22.3 and murine chromosome 17B/C
    • Berthelsen,J., Viggiano,L., Schulz,H., Ferretti,E., Consalez,G.G., Rocchi,M. and Blasi,F. (1998) PKNOX1, a gene encoding PREP1, a new regulator of Pbx activity, maps on human chromosome 21q22.3 and murine chromosome 17B/C. Genomics, 47, 323-324.
    • (1998) Genomics , vol.47 , pp. 323-324
    • Berthelsen, J.1    Viggiano, L.2    Schulz, H.3    Ferretti, E.4    Consalez, G.G.5    Rocchi, M.6    Blasi, F.7
  • 15
    • 0038606993 scopus 로고    scopus 로고
    • Overexpression of FABP7 in Down syndrome fetal brains is associated with PKNOX1 gene-dosage imbalance
    • Sanchez-Font,M.F., Bosch-Comas,A., Gonzalez-Duarte,R. and Marfany,G. (2003) Overexpression of FABP7 in Down syndrome fetal brains is associated with PKNOX1 gene-dosage imbalance. Nucleic Acids Res., 31, 2769-2777.
    • (2003) Nucleic Acids Res , vol.31 , pp. 2769-2777
    • Sanchez-Font, M.F.1    Bosch-Comas, A.2    Gonzalez-Duarte, R.3    Marfany, G.4
  • 16
    • 0141865762 scopus 로고    scopus 로고
    • Overexpression of PREP-1 in F9 teratocarcinoma cells leads to a functionally relevant increase of PBX-2 by preventing its degradation
    • Longobardi,E. and Blasi,F. (2003) Overexpression of PREP-1 in F9 teratocarcinoma cells leads to a functionally relevant increase of PBX-2 by preventing its degradation. J. Biol. Chem., 278, 39235-39241.
    • (2003) J. Biol. Chem. , vol.278 , pp. 39235-39241
    • Longobardi, E.1    Blasi, F.2
  • 17
    • 0035934254 scopus 로고    scopus 로고
    • Cloning and characterization of murine p53 upstream sequences reveals additional positive transcriptional regulatory elements
    • Reisman,D., Eaton,E., McMillin,D., Doudican,N.A. and Boggs,K. (2001) Cloning and characterization of murine p53 upstream sequences reveals additional positive transcriptional regulatory elements. Gene, 274, 129-137.
    • (2001) Gene , vol.274 , pp. 129-137
    • Reisman, D.1    Eaton, E.2    McMillin, D.3    Doudican, N.A.4    Boggs, K.5
  • 18
    • 0032473352 scopus 로고    scopus 로고
    • Prep1, a novel functional partner of Pbx proteins
    • Berthelsen,J., Zappavigna,V., Mavilio,F. and Blasi,F. (1998) Prep1, a novel functional partner of Pbx proteins. EMBO J., 17, 1423-1433.
    • (1998) EMBO J , vol.17 , pp. 1423-1433
    • Berthelsen, J.1    Zappavigna, V.2    Mavilio, F.3    Blasi, F.4
  • 19
    • 34250344226 scopus 로고    scopus 로고
    • A transcription-dependent micrococcal nuclease-resistant fragment of the urokinase-type plasminogen activator promoter interacts with the enhancer
    • Ferrai,C., Munari,D., Luraghi,P., Pecciarini,L., Cangi,M.G., Doglioni,C., Blasi,F. and Crippa,M.P. (2007) A transcription-dependent micrococcal nuclease-resistant fragment of the urokinase-type plasminogen activator promoter interacts with the enhancer. J. Biol. Chem., 282, 12537-12546.
    • (2007) J. Biol. Chem. , vol.282 , pp. 12537-12546
    • Ferrai, C.1    Munari, D.2    Luraghi, P.3    Pecciarini, L.4    Cangi, M.G.5    Doglioni, C.6    Blasi, F.7    Crippa, M.P.8
  • 20
    • 30844459649 scopus 로고    scopus 로고
    • Specific immunofluorimetric assay detecting the chemotactic epitope of the urokinase receptor (uPAR)
    • Resnati,M., Pallavicini,I., Daverio,R., Sidenius,N., Bonini,P. and Blasi,F. (2006) Specific immunofluorimetric assay detecting the chemotactic epitope of the urokinase receptor (uPAR). J. Immunol. Methods, 308, 192-202.
    • (2006) J. Immunol. Methods , vol.308 , pp. 192-202
    • Resnati, M.1    Pallavicini, I.2    Daverio, R.3    Sidenius, N.4    Bonini, P.5    Blasi, F.6
  • 21
    • 1542353401 scopus 로고    scopus 로고
    • Control of apoptosis by p53
    • Fridman,J.S. and Lowe,S.W. (2003) Control of apoptosis by p53. Oncogene, 22, 9030-9040.
    • (2003) Oncogene , vol.22 , pp. 9030-9040
    • Fridman, J.S.1    Lowe, S.W.2
  • 22
    • 0033552595 scopus 로고    scopus 로고
    • Regulation of p53 in response to DNA damage
    • Lakin,N.D. and Jackson,S.P. (1999) Regulation of p53 in response to DNA damage. Oncogene, 18, 7644-7655.
    • (1999) Oncogene , vol.18 , pp. 7644-7655
    • Lakin, N.D.1    Jackson, S.P.2
  • 25
    • 0028292480 scopus 로고
    • Identification of a p53-dependent negative response element in the bcl-2 gene
    • Miyashita,T., Harigai,M., Hanada,M. and Reed,J.C. (1994) Identification of a p53-dependent negative response element in the bcl-2 gene. Cancer Res., 54, 3131-3135.
    • (1994) Cancer Res , vol.54 , pp. 3131-3135
    • Miyashita, T.1    Harigai, M.2    Hanada, M.3    Reed, J.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.