Maternal caffeine intake during gestation and lactation down-regulates adenosine A1 receptor in rat brain from mothers and neonates

Journal of Neuroscience Research

Volumn 88, Issue 6, 2010, Pages 1252-1261

  Lorenzo, A M ^a   Leon D ^a   Castillo, C A ^a   Ruiz, M A ^a   Albasanz, J L ^a   Martín, Mairena ^a  

^a UNIVERSITY OF CASTILLA LA MANCHA   (Spain)

Author keywords

Adenosine receptor; Methylxanthine; Neonates; Pregnancy

Indexed keywords

ADENOSINE A1 RECEPTOR; CAFFEINE; COMPLEMENTARY DNA; DRINKING WATER; MESSENGER RNA; METHYLXANTHINE; RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; FOOD INTAKE; GESTATION PERIOD; GESTATIONAL AGE; LACTATION; LOCOMOTION; LONG TERM EXPOSURE; MOTOR ACTIVITY; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; RADIOASSAY; RAT; REAL TIME POLYMERASE CHAIN REACTION;

ANIMALS; ANIMALS, NEWBORN; BRAIN; CAFFEINE; CENTRAL NERVOUS SYSTEM STIMULANTS; FEMALE; LACTATION; MALE; MOTOR ACTIVITY; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, WISTAR; RECEPTOR, ADENOSINE A1; RECEPTORS, ADENOSINE A2; RNA, MESSENGER; SEX CHARACTERISTICS; TIME FACTORS;

EID: 77951575594     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22287     Document Type: Article

References (39)

1. Adén U, Herlenius E, Tang LQ, Fredholm BB. 2000. Maternal caffeine intake has minor effects on adenosine receptor ontogeny in the rat brain. Pediatr Res 48:177-183 (Pubitemid 30497334)
2. 2A receptors are up-regulated in Pick's disease frontal cortex. Brain Pathol 16:249-255.
3. Bona E, Aden U, Fredholm BB, Hagberg H. 1995. The effect of long term caffeine treatment on hypoxic-ischemic brain damage in the neonate. Pediatr Res 38:312-318.
4. Bracken MB, Triche EW, Belanger K, Hellenbrand K, Leaderer BP. 2003. Association of maternal caffeine consumption with decrements in fetal growth. Am J Epidemiol 157:456-466. (Pubitemid 36258601)
5. Comer AM, Perry CM, Figgitt DP. 2001. Caffeine citrate: a review of its use in apnoea of prematurity. Pediatr Drugs 1:61-79.
6. da Silva RS, Richetti SK, da Silveira VG, Battastini AM, Bogo MR, Lara DR, Bonan CD. 2008. Maternal caffeine intake affects acetylcholinesterase in hippocampus of neonate rats. Int J Dev Neurosci 26:339-343.
7. 1 adenosine receptors: morphological evidence of endosomal sorting and receptor recycling. Experimental cell research 285:72-90.
8. 1 receptor ontogeny using autoradiography. Brain Res Dev Brain Res 82:223-230.
9. Fredholm BB. 2003. Caffeine and the biological role of adenosine receptors. Anal Real Acad Nal Farm 69:133-167.
10. Fredholm BB, Bättig K, Holmén J, Nehlig A, Zvartau EE. 1999. Actions of caffeine in the brain with special reference to factors that contribute to its widespread use. Pharmacol Rev 1:83-133. (Pubitemid 29113867)
11. 1 receptor distribution in respiration-related nuclei of the rat brainstem. Auton Neurosci 126-127:339-346.
12. 1 receptors in brain of rats. Neuropharmacology 5:489-496.
13. Higuchi R, Fockler C, Dollinger G, Watson R. 1993. Kinetic PCR analysis: real-time monitoring of DNA amplification reactions. Biotechnology 11:1026-1030. (Pubitemid 23254023)
14. Holtzman SG, Finn IB. 1988. Tolerance to behavioral effects of caffeine in rats. Pharmacol Biochem Behav 2:411-418.
15. 1 and A2 adenosine receptor binding and on mRNA levels in rat brain. Naunyn Schmiedebergs Arch Pharmacol 347:407-414.
16. 1 mRNA in mouse brain: effect of long-term caffeine treatment. Brain Res 762:153-164.
17. 2A receptors in rat brain: comparison with dopamine receptors. Neuroscience 4:1187-1207.
18. 1 adenosine receptor binding. J Pharmacol Exp Ther 3:1563-1572.
19. 2A receptors in the motor effects of caffeine after its acute and chronic administration. Neuropsychopharmacology 7:1281-1291.
20. Klebanoff MA, Levine RJ, Clemens JD, Wilkins DG. 2002. Maternal serum caffeine metabolites and small-for-gestational age birth. Am J Epidemiol 155:32-37.
21. Lau CE, Falk JL. 1994. Tolerance to oral and IP caffeine: locomotor activity and pharmacokinetics. Pharmacol Biochem Behav 2:337-344.
22. Lau CE, Falk JL. 1995. Dose-dependent surmountability of locomotor activity in caffeine tolerance. Pharmacol Biochem Behav 1:139-143.
23. 1 receptor down-regulation in mothers and fetal brain after caffeine and theophylline treatments to pregnant rats. J Neurochem 82: 625-634.
24. 1 receptors at the end of pregnancy. J Neurochem 88:993-1002.
25. Natarajan G, Botica ML, Thomas R, Aranda JV. 2007. Therapeutic drug monitoring for caffeine in preterm neonates: an unnecessary exercise? Pediatrics 119:936-940.
26. Nealis JET, Rosman NP, DePiero TJ. 1978. Neurological sequelae of experimental febrile convulsions. Neurology 28:246-250
27. Nikodijević O, Jacobson KA, Daly JW. 1993. Locomotor activity in mice during chronic treatment with caffeine and withdrawal. Pharmacol Biochem Behav 1:199-216. (Pubitemid 23025308)
28. Pan HZ, Chen HH. 2007. Hyperalgesia, low-anxiety, and impairment of avoidance learning in neonatal caffeine-treated rats. Psychopharmacology 191:119-125.
29. Picard N, Guénin S, Larnicol N, Perrin Y. 2008. Maternal caffeine ingestion during gestation and lactation influences respiratory adaptation to acute alveolar hypoxia in newborn rats and adenosine A(2A) and GABA(A) receptor mRNA transcription. Neuroscience 156:630-639.
30. Pichini S, Altieri I, Zuccaro P, Pacifici R. 1996. Drug monitoring in nonconventional biological fluids and matrices. Clin Pharmacokinet 30: 211-228. (Pubitemid 26093250)
31. Ralevic V, Burnstock G. 1998. Receptors for purines and pyrimidines. Pharmacol Rev 50:413-492.
32. Rosin DL, Robeva A, Woodard RL, Guyenet PG, Linden J. 1998. Immunohistochemical localization of adenosine A2A receptors in the rat central nervous system. J Comp Neurol 401:163-186. (Pubitemid 28481960)
33. 1 receptors in rat brain by in vivo treatment with R-PIA: involvement of coated vesicles. Biochim Biophys Acta 1310:168-174.
34. 1 adenosine receptors internalize together following agonist-induced receptor desensitization. J Biol Chem 273:17610-17617.
35. Svenningsson P, Nomikos GG, Fredholm BB. 1999. The stimulatory action and the development of tolerance to caffeine is associated with alterations in gene expression in specific brain regions. J Neurosci 19: 4011-4022. (Pubitemid 29222274)
36. Tofovic SP, Kost CK Jr, Jackson EK, Bastacky SI. 2002. Long-term caffeine consumption exacerbates renal failure in obese, diabetic, ZSF1 (fa-fa(cp)) rats. Kidney Int 61:1433-1444.
37. Tracy TS, Venkataramanan R, Glover DD, Caritis SN;National Institute for Child Health and Human Development Network of Maternal-Fetal-Medicine Units. 2005. Temporal changes in drug metabolism (CYP1A2, CYP2D6, and CYP3A activity) during pregnancy. Am J Obstet Gynecol 192:633-639.
38. von Lubitz DK. 1999. Adenosine and cerebral ischemia: therapeutic future or death of a brave concept? Eur J Pharmacol 371:85-102.
39. Weng X, Odouli R, Li DK. 2008. Maternal caffeine consumption during pregnancy and the risk of miscarriage: a prospective cohort study. Am J Obstet Gynecol 198:279.